ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)


Volume 12, 8 Issues, 2016


Download PDF Flyer




Medicinal Chemistry

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Atta-ur-Rahman
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: mc@benthamscience.org

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 1.363
5 - Year: 1.388

Upcoming Articles (E-Pub Abstracts ahead of Print)

Synthesis and evaluation of phenyliminoindolin-containing phenylacetamide derivatives with the antidepressant and anticonvulsant effects


Li-Ping Guan, Bing-Yu Liu, Ying-Chun Quan, Li-Ye Yang, Xing-Hua Zhen and Si-Hong Wang.


View Abstract


Synthesis, Antibacterial Activity, Interaction with Nucleobase and Molecular Docking Studies of 4-Formylbenzoic Acid Based Thiazoles


Krzysztof Z. Łączkowski, Anna Biernasiuk, Angelika Baranowska-Łączkowska, Konrad Misiura, Anna Malm, Tomasz Plech and Agata Paneth.


View Abstract


Ether and carbamate derivatives of 3-quinuclidinol and 3-hydroxymethylquinuclidine: synthesis and evaluation as nicotinic ligands


Sivakumar Annadurai, Min Zhang, Jerome L. Gabriel, Merouane Bencheriff and Daniel J Canney.


View Abstract


In-Vitro Anticancer Evaluation and Docking Study of Novel benzo[g] quinazoline-sulfonamide Derivatives


Mostafa M. Ghorab, Mansour S. Alsaid, Mohamed S. Al-Dosary and Marwa G El-Gazzar.


View Abstract


Synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives incorporating benzisoselenazolone scaffold as potential antitumor agents


Xiaoyun Fu, Sha Li, Fen Jing, Xuefeng Wang, Baolin Li, Jijun Zhao, Yuming Liu and Baoquan Chen.


View Abstract


Efficient Synthesis and Discovery of Schiff Bases as Potent Cholinesterase Inhibitors


Basma M. Abd Razik, Hasnah Osman, Mohammed Oday Ezzat, Alireza Basiri, Abdussalam Salhin, Yalda Kia and Vikneswaran Murugaiyah.


View Abstract


Nitazoxanide Analogues as Antimicrobial Agents against Nosocomial Pathogens


Jia-Suey Gau, Wen-Pao Lin, Li-Ching Kuo and Ming-Kuan Hu.


View Abstract


Synthesis, in vivo anticoagulant evaluation and molecular docking studies of bicoumarins obtained from furocoumarin peucedanin


Alla V. Lipeeva, Mikhail V. Khvostov, Dmitry S. Baev, Makhmut M. Shakirov, Tatijana G. Tolstikova and Elvira E Shults.


View Abstract


Biologically Active New N, N', N''-Tri-Substituted Ferrocenyl Phenylguanidines and their Characterization


Rukhsana Gul, Ataf Ali Altaf, Azim Khan, Amin Badshah, Afzal Shah, Zia ur Rehman, Rabia Naz, Muhammad Nawaz Tahir and Asif Junaid.


View Abstract


Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic systems against B16-F10 Melanoma Cancer Cells


Duc Duy Vo, Isabelle Rouaud, Francoise Le Devehat, Fabien Gautier, Sophie Barillé-Nion, Philippe Juin, Nicolas Levoin, Joël Boustie and René Grée.


View Abstract


Competitive Interaction Between Plasma Omega-3 Fatty Acids and Arachidonic Acid is Related to Down-Regulation of A Signaling Mediator


Kunio Yui, George Imataka and Yohei Kawasaki.


View Abstract


Synthesis, Biological Evaluation and Pharmacokinetic Studies of Mefenamic Acid - N-Hydroxymethylsuccinimide Ester Prodrug as Safer NSAID


Asif Husain, Priyanka Ahuja, Aftab Ahmad and Shah Alam Khan.


View Abstract


Design, Synthesis and Antiproliferative Activity of Novel Benzothiazole Derivatives Conjugated with Semicarbazone Scaffold


Guanglong Bao, Baoquan Du, Yuxiu Ma, Meng Zhao, Ping Gong and Xin Zhai.


View Abstract


Facing Chagas’ disease: trypanocidal properties of new coumarin-chalcone scaffolds


Saleta Vazquez-Rodriguez, Roberto Figueroa Guíñez, Maria João Matos, Claudio Olea-Azar, Juan Diego Maya, Eugenio Uriarte and Lourdes Santana.


View Abstract


Identification of New Inhibitors for Human SIRT1: An in-silico Approach


Balasundaram Padmanabhan, Manjula Ramu, Sruti Mathur, Sruthi Unni and Saravanamuthu Thiyagarajan.


View Abstract


The current use of mass spectrometry in combination with other separation techniques in drug discovery arena


Piotr Kawczak and Tomasz Bączek.


View Abstract


Design, Synthesis, and Cytotoxicity of Novel 2,4,6-Trisubstituted 1,3,5-triazines Bearing Aryl Hydrazone Moiety as Potent Antitumor Agent


Limei Wang, Sijia Zhao, Guanglong Bao, Yu Zhang, Shuancheng Xi, Guolin Zhou, Xin Zhai and Ping Gong.


View Abstract


Antiplasmodial Limonoids from Trichilia rubescens (Meliaceae)


Tsamo Tontsa Armelle, Nangmo Kemda Pamela, Mkounga Pierre, Ingrid B. Müller, Kirk Marat, Gabriele Sass and Nkengfack Augustin Ephrem.


View Abstract


Discovery and optimization of 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-(amino)pyridin-3-yl)ureas as novel KDR kinase inhibitors


Yu Jiao, Fei Huang, Pengfei Xu, Yanmin Zhang, Shangyan Yang, Danfeng Zhang, Tao Lu and Weifang Tang.


View Abstract


Antimicrobial and Anti-Biofilm Activity of Thiourea Derivatives Bearing 3-Amino-1H-1, 2, 4-Triazole Scaffold


Joanna Stefanska, Karolina Stepien, Anna Bielenica, Daniel Szulczyk, Barbara Miroslaw, Anna E Koziol, Giuseppina Sanna, Filippo Iuliano, Silvia Madeddu, Michal Jozwiak and Marta Struga.


View Abstract


Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach


Engi A. Hassaan, Sara C. Sigler, Tamer M. Ibrahim, Kevin J. Lee, Lauren K. Cichon, Bernard D. Gary, Joshua C. Canzoneri, Gary A. Piazza and Ashraf HAbadi.


View Abstract


Serum Tumor Markers in Stage I-II Breast Cancer


Renato Tozzoli, Federica D'Aurizio, Flavio Falcomer, Stefano M.M. Basso and Franco Lumachi.


View Abstract


Adjuvant Treatment of Early Breast Cancer in the Elderly


Giovanni M. Fadda, Davide A. Santeufemia, Stefano M.M. Basso, Renato Tozzoli, Flavio Falcomer and Franco Lumachi.


View Abstract


Advances in the Treatment of Triple-negative Early Breast Cancer


Stefano M.M. Basso, Davide A. Santeufemia, Giovanni M. Fadda, Renato Tozzoli, Federica D'Aurizio and Franco Lumachi.


View Abstract


Chemosensitization of prostate carcinoma cells with a receptor-directed Smac conjugate


Alexander Sturzu, Sumbla Sheikh, Hartmut Echner, Martin Deeg, Thomas Nägele, Christopher Weidenmaier, Christian Schwentner, Marius Horger, Ulrike Ernemann and Stefan Heckl.


View Abstract


Synthesis, structural characterization of a novel ferrocene derivative and preliminarily anticancer activity


Jianping Yong, Xiaoyuan Wu, Jianzhen Liao, Canzhong Lu and Xiaolong Liu.


View Abstract


Synthesis, Molecular Docking Study, and Cytotoxic Activity of 3,4-diaryl-5-(4-pyridinyl)-1,2,4-oxadiazole


Bita Zareian, Sajad Ghadbeighi, Amirali Amirhamzeh, Seyed Nasser Ostad, Abbas Shafiee and Mohsen Amini.


View Abstract


Design, Synthesis, and Fungicidal Activities of Novel 5-Methyl-1H-1,2,3-trizole-4-carboxyl Amide Analogues


Zhen-Jun Wang, Hui-Hui Yang, Lei Tian and Wei-Guang Zhao.


View Abstract


DNA Hybridization on Chitosan-Functionalized Silicon Substrate


Amina Omar, El-Sayed M. El-Sayed, Mona S. Talaat and Medhat Ibrahim.


View Abstract


Design, Synthesis and Structure-Activity Relationship Studies of Novel 4-(1-adamantyl) Phenyl Analogues as HIF-1α Inhibitors


Yan Xia, Qiong Duan, Bao-Hua Zhao, Dong-Feng Li and Rui-Bin Hou.


View Abstract


Withanolides: Biologically Active Constituents in the Treatment of Alzheimer Disease


Shahid Ali Khan, Sher Bahadar Khan, Zarbad Shah and Abdullah M Asiri.


View Abstract


miRNAs as Circulating Biomarkers for Alzheimer’s Disease and Parkinson’s Disease


Gohar Mushtaq, Nigel H. Greig, Firoz Anwar, Mazin A. Zamzami, Hani Choudhry, Munvar Miya Shaik, Ian A. Tamargo and Mohammad A Kamal.


View Abstract


Recent updates on the association between Alzheimer’s disease and vascular dementia


Ghulam Md Ashraf, Sandesh Chibber, Mohammad, Syed Kashif Zaidi, Shams Tabrez, Ausaf Ahmad, Shazi Shakil, Gohar Mushtaq, Saleh Salem Baeesa and Mohammad Amjad Kamal.


View Abstract


Antioxidant, Antimicrobial Activity and Medicinal Properties of Grewia asiatica L.


Ritu Shukla, Dinesh C. Sharma, Mohd. Hassan Baig, Shabana Bano, Sudeep Roy, Ivo Provazník and Mohammad Amjad Kamal.


View Abstract


Chemical Composition and Inhibitory Effects of Hypericum brasiliense and H. connatum on Prolyl oligopeptidase and Acetylcholinesterase Activities


Maura Z. dos Santos, Ionara I. Dalcol, Luciana Adolpho, Meritxell Teixidó, Teresa Tarragó, Ademir Morel and Ernest Giralt.


View Abstract


Growth Factors and Astrocytes Metabolism: Possible Roles for Platelet Derived Growth Factor


Ricardo Cabezas, Marco Avila-Rodriguez, Nelson Enrique Vega-Vela, Valentina Echeverria, Janneth González, Oscar Alejandro Hidalgo, Altair Brito Santos, Gjumrakch Aliev and George E Barreto.


View Abstract


Robust Modeling and Scaffold Hopping: Case Study based on HIV Reverse Transcriptase Inhibitors Type-1 Data


Girinath G. Pillai, Laznier Mederos, Chandramukhi S. Panda, Amber Gronski, Peeter Burk, C. Dennis Hall, Alan R. Katritzky, Kaido Tämm and Mati Karelson.


View Abstract


The Brain Protective Effect of rTMS (Repetitive Transcranial Magnetic Stimulation) in Depression: A Mini-Review in Animal Studies


Burak Yulug, Lütfü Hanoglu, Ahmet Mithat Tavli, Nesrin Helvacı Yılmaz and Ertugrul Kılıc.


View Abstract


Identification of Bostrycin Derivatives as Potential Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase (MptpB)


Dong-ni Chen, Hong Chen, Zhi-gang She and Yong-jun Lu.


View Abstract


Cytotoxic Effects of Salvinorin A, A Major Constituent of Salvia divinorum


Ana Martinho, Sara M. Silva and Eugenia Gallardo.


View Abstract


QSRR and QSAR Studies of Antitumor Drugs In View of their Biological Activity Prediction


Paulina Szatkowska-Wandas, Marcin Koba, Grzegorz Smoliński and Jacek Wandas.


View Abstract


Pharmacophore and QSAR Modeling of Neuronal Nitric Oxide Synthase Ligands and Subsequent Validation and In Silico Search for New Scaffolds


Ghadeer Suaifan, Mayadah Shehadeh, Hebah Al-Ijel, Khuloud Al-Jamal and Mutasem Taha.


View Abstract


Monooxime Bispyridinium Reactivators Bearing Xylene Linker – Synthesis and In Vitro Evaluation on Model of Organophosphate-Inhibited Acetylcholinesterase


Kamil Musilek, Jan Hambalek, Ondrej Holas, Vlastimil Dohnal and Kamil Kuca.


View Abstract


Synthesis and Anti-Thyroid Cancer Effect of Iodo-Chrysin Derivatives


Yun Wei, Qutong Zheng, Guotao Tang, Chen Song, Guan Wang, Yinxiang Zhang, Yan Xiao, Xianliang Zeng, Zongbao Wang, Jichang Xiao and Xing Zheng.


View Abstract


Synthesis, in Vitro Biological Screening and Molecular Docking Studies of Novel Camphor Based Thiazoles


Krzysztof Z. Łączkowski, Konrad Misiura, Anna Biernasiuk, Anna Malm, Agata Siwek, Tomasz Plech, Emilia Ciok-Pater, Krzysztof Skowron and Eugenia Gospodarek.


View Abstract


Advertisement
Global Biotechnology Congress 2016Drug Discovery and Therapy World Congress 2016

Related Journals




Related eBooks


Webmaster Contact: urooj@benthamscience.org Copyright © 2016 Bentham Science