ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)


Volume 11, 8 Issues, 2015


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Medicinal Chemistry

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Editor-in-Chief:
Atta-ur-Rahman
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Kings College
University of Cambridge
Cambridge
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Email: mc@benthamscience.org

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Upcoming Articles (E-Pub Abstracts ahead of Print)

Synthesis, Characterization, Antimicrobial and Antitumor Activities of Sucrose Octa(N-ethyl)carbamate


Claudia D. Raposo, Krasimira T. Petrova, M. Teresa Barros, Ricardo C. Calhelha, Marina Sokovic and Isabel C F R Ferreira.


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2-Arylquinazolin-4(3H)-ones: Inhibitory Activities against Xanthine Oxidase


Humaira Zafar, Syed Muhammad Saad, Shahnaz Perveen, Arshia, Rizwana Malik, Ajmal Khan, Khalid Mohammed Khan and M Iqbal Choudhary.


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Investigation of the Antimycobacterial Activity of 8-Hydroxyquinolines


Wioleta Cieslik, Ewelina Spaczynska, Katarzyna Malarz, Dominik Tabak, Eoghan Nevin, Jim O'Mahony, Aidan Coffey, Anna Mrozek-Wilczkiewicz, Josef Jampilek and Robert Musiol.


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3D-QSAR Studies on Flavone-8-acetic Acid Derivatives of Aminopeptidase N Inhibitors


XianShuai Tang, QingLian Qu, BinHai Kuang, ShaoHua Li and GuoGang Tu.


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Discovery of Multi-target Anticancer Agents based on HDAC inhibitor MS-275 and 5-FU


Yuqi Jiang, Xiaoguang Li, Xiaoyang Li, Jinning Hou, Yongzheng Ding, Jian Zhang, Yingjie Zhang and Wenfang Xu.


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Pharmacophore-Based Virtual Screening for Identification of Novel Neuraminidase Inhibitors and Verification of Inhibitory Activity by Molecular Docking


Sidra Batool, Gohar Mushtaq, Warda Kamal and Mohammad Amjad Kamal.


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Synthesis, Anticancer Evaluation and Docking Study of 3-Benzyloxyhydantoin Derivatives


Jun Liu, Kai Zhang, Xi Mai, Jinjin Wei, Yijing Liao, Ying Zhong, Yang Liu, Lihua Feng and Chao Liu.


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Biological Evaluation of Azomethine-Dihydroquinazolinone Conjugates as Cancer and Cholinesterase Inhibitors


Jamshed Iqbal, Aamer Saeed, Syed Jawad Ali Shah, Mariya al-Rashida and Shams-ul Mahmood.


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Novel 3-Substituted-2-Oxoindoline-Based N-hydroxypropenamides as Histone Deacetylase Inhibitors and Antitumor Agents


Do Thi Mai Dung, Phan Thi Phuong Dung, Dao Thi Kim Oanh, Pham The Hai, Le Thi Thu Huong, Vu Duc Loi, Hyunggu Hahn, Byung Woo Han, Jisung Kim, Sang-Bae Han and Nguyen-Hai Nam.


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In Silico Screening for Identification of Novel Anti-Malarial Inhibitors by Molecular Docking, Pharmacophore Modeling and Virtual Screening


Sidra Batool, Zeshan Aslam Khan, Warda Kamal, Gohar Mushtaq and Mohammad Amjad Kamal.


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Molecular Modeling, Synthesis and Pharmacological Evaluation of 1,3,4-Thiadiazoles as Anti-Inflammatory and Analgesic Agents


Anas H.M. Shkair, Ashok K. Shakya, N.M. Raghavendra and Rajashri R Naik.


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Hepatoprotective Effects of Polysaccharides from Selenium-Enriched Pyracantha fortuneana on Mice Liver Injury


Chengfu Yuan, Zhihong Li, Muhua Yi, Xiaoxing Wang, Fan Peng, Fangxiang Xiao, Tao Chen, Changdong Wang, Gohar Mushtaq and Mohammad Amjad Kamal.


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Design, Synthesis and QSAR Studies on a Series of 2, 5-Disubstituted-1,3,4-oxadiazole Derivatives of Diclofenac and Naproxen For Analgesic and Anti-inflammatory activity


K. Ilango, P. Valentina, Gajendra Kumar, Dushyant Dixit, Shrikant Nilewar and M K Kathiravan.


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New N, N,N’,N’-Tetradentate Pyrazoly Agents: Synthesis and Evaluation of their Antifungal and Antibacterial Activities


Farid Abrigach, Btissam Bouchal, Olivier Riant, Yohan Mace, Abdelilah Takfaoui, Smaail Radi, Abdelouahad Oussaid, Mohammed Bellaoui and Rachid Touzani.


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Compounds Combining Aminoadamantane and Monoterpene Moieties: Cytotoxicity and Mutagenic Effects


Evgeniy V. Suslov, Konstantin Yu. Ponomarev, Artem D. Rogachev, Michail A. Pokrovsky, Andrey G. Pokrovsky, Maria B. Pykhtina, Anatoly B. Beklemishev, Dina V. Korchagina, Konstantin P. Volcho and Nariman F Salakhutdinov.


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a-Aminoisobutyric Acid Leads a Fluorescent Syn-Bimane Laser Probe Across the Blood-Brain Barrier


Inbal Lapidot, Danny Baranes, Albert Pinhasov, Gary Gellerman, Amnon Albeck, Flavio Grynszpan and Shimon E Shatzmiller.


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Thiosemicarbazone-Pt(II) Complex Causes a Growth Inhibitory Effect on Human Mesenchymal Stem Cells


J.P. Garcia-Ruiz, A.I. Matesanz, A. Perez and P Souza.


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Synthesis of Daumone Derivatives and their Antiangiogenic Activities on Chorioallantoic Membrane


Jeremy Ricci, Dongguk Min, Miyeon Oh, Hyenchong Lim, Won-Yoon Chung, Kwang-Kyun Park and Mankil Jung.


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Molecular Design, Synthesis and Evaluation of 2,3-Diarylquinoxalines as Estrogen Receptor Ligands


Diego P. Sangi, Marcia R. Cominetti, Amanda B. Becceneri, Flavia A. Resende, Eliana A. Varanda, Carlos A. Montanari, Marcio W. Paixao and Arlene G Correa.


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Preparation and Biodistribution of Technetium-99m-Labeled Bis-Misonidazole (MISO) as an Imaging Agent for Tumour Hypoxia


Feng Wang, D i Fan, Jun Qian, Zhe Zhang, Jianhua Zhu and Jian Chen.


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Exploring the Synthesis and Anticancer Potential of L-Tyrosine-Platinum(II) Hybrid Molecules


Caroline Descôteaux, Kevin Brasseur, Valérie Leblanc, Eric Asselin and Gervais Bérubé.


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Design, Synthesis and Biological Evaluation of Palladium (II) Complexes with 1-(Substituted Benzyl) Azetidine-3,3-Dicarboxylates as Leaving Group


X u Gang, L u Hua, Jiang Zhitao, Shuying Zhang and Shaohua Gou.


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Synthesis and Antibacterial Activity of Novel Quaternary Ammonium Pyridoxine Derivatives


Nikita V. Shtyrlin, Sergey V. Sapozhnikov, Sergey A. Koshkin, Alfiya G. Iksanova, Arthur H. Sabirov, Airat R. Kayumov, Aliya A. Nureeva, Marina I. Zeldi and Yurii G Shtyrlin.


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Regioselective Synthesis of 2-Chloroquinoline Based Ethyl 4-(3-Hydroxyphenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydroquinoline-3-Carboxylates and their In-Silico Evaluation Against P. falciparum Lactate Dehydrogenase


K. Rajesh, P. Lavanya, P. Iniyavan, S. Sarveswari, Sudha Ramaiah, Anand Anbarasu and V Vijayakumar.


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Antimicrobial and Anti-Inflammatory Activities of Ppc-1, Active Principle of the Cellular Slime Mold Polysphondylium Pseudo-Candidum


Jabrane Azelmat, Serena Fiorito, Salvatore Genovese, Francesco Epifano and Daniel Grenier.


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Roles of Natural Compounds from Medicinal Plants in Cancer Treatment: Structure and Mode of Action at Molecular Level


Mahmood Rasool, Arif Malik, Mahwish Arooj, Abdul Manan, Mahmood Husain Qazi, Mohammad Amjad Kamal, Ishfaq Ahmed Sheikh, Siew Hua Gan, Muhammad Asif and Muhammad Imran Naseer.


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Synthesis and Anti-tumor Activities of Novel Phenyl Substituted Suberoylanilide Hydroxamic Acid Derivatives against Human Cancer Cells


Rui Xie, Jinghua Shi, Yue Qu, Pingwah Tang, Xinying Wu, Ming Yang and Qipeng Yuan.


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Psychosis and Gestational Influenza: Meta-Analysis


Lei Cai, Chun-Lin Wan, Lin He, Simone de Jong and Kuo-Chen Chou.


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Studies on Chemistry, Spectroscopy and Antioxidant Activities of Chromium(III)-Hydrazide Complexes


Bushra Shamshad, Rifat Ara Jamal, Uzma Ashiq, Mohammad Mahrooof-Tahir, Zara Shaikh, Sadaf Sultan and Khalid Mohammed Khan.


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Recognition and Impact of Host-Derived Molecules on Bacterial Cell-to-Cell Signalling Pathways


Alina-Maria Holban, Mariana Carmen Chifiriuc and Veronica Lazar.


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Synthesis, in Vitro Biological Screening and Molecular Docking Studies of Novel Camphor Based Thiazoles


Krzysztof Z. Łączkowski, Konrad Misiura, Anna Biernasiuk, Anna Malm, Agata Siwek, Tomasz Plech, Emilia Ciok-Pater, Krzysztof Skowron and Eugenia Gospodarek.


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