ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 11, 10 Issues, 2014


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Letters in Drug Design & Discovery

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

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Upcoming Articles (E-Pub Abstracts ahead of Print)

Controlled Release from Solid Pharmaceutical Formulations of two N-Alkanoyl-4-Methoxybicyclo [4.2.0] Octa-1, 3, 5-Trien-7-Ethanamines with Melatoninergic Activity
Marilena Vlachou, Vasiliki Ioannidou, Maria Vertzoni, Andrew Tsotinis, Pandelis A. Afroudakis and David Sugden
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Discovery of Novel HDAC Inhibitors by Structure-Based Optimization of Cinnamic Hydroxamic Scaffold
Chengqing Ning, Wenyuan Huang, Wen Wu, Cheng Lu, Yujun He, Lei Yao, Lifei Liu, Xiaohe Zhen, Xiaoyu Liu and Niefang Yu
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Docking Study of Novel Pyrrolidine Derivatives as Potential Dipeptidyl Peptidase-Iv (Dpp-Iv) Inhibitors
Sant Kumar Verma, Shashi Kant Sharma and Suresh Thareja
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Role of Curcumin in Modulating Plasma PON1 Arylesterase Activity and Susceptibility to LDL Oxidation in Oxidatively Challenged Wistar Rats
Prabhakar Singh and Syed Ibrahim Rizvi
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The Synthesis of Risedronic Acid and Alendronate Applying Phosphorus Oxychloride and Phosphorous Acid in Methanesulfonic Acid
Alajos Grun, Rita Kovacs, Sandor Garadnay, Istvan Greiner and Gyorgy Keglevich
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The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy
Joanna Cytarska, Krzysztof Skowerski, Szymon Jaworski, Konrad Misiura, Beata Filip-Psurska and Joanna Wietrzyk
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Synthesis and Biological Activity of Acylthiourea Derivatives Contain 1,2,3-Thiadiazole and 1,3,4-Thiadiazole
Ming-Yan Yang, Wen Zhao, Zhao-Hui Sun, Cheng-Xia Tan, Jian-Quan Weng and Xing-Hai Liu
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Development of Structure Activity Correlation Model on Azetidin-2-ones as Tubulin Polymerization Inhibitors
Vijay K. Patel, Kavibhushan S. Chouhan, Avineesh Singh, Deepak K Jain, Ravichandran Veerasamy, Pradeep K. Singour, Rajesh S. Pawar and Harish Rajak
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Synthesis and Biological Evaluations of Novel Nitric Oxide-donating Derivatives of [1,2,4]triazol-5(4H)-one with N-phenylpyrrolyl-2-tetrazole Moiety as Anti-hypertension Candidates
Yanchun Zhang, Jinyi Xu, Jinpei Zhou and Xiaoming Wu
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First Discovery of Tylophora Alkaloids as HIV Inhibitors
Ziwen Wang, Mingxiao Wang, Lei Wang, Xue Yao, Yue Li, Juan Tan, Wentao Qiao, Yunqi Geng, Yuxiu Liu and Qingmin Wang
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The Novel Derivatives of 3-(Iminomethyl)-2H-Chromen-2-one with Thiourea and Piperazine Structural Motive:Rationale, Synthesis, Antimicrobial and Anti-TB Evaluation
Harshad P. Lakum, Dhruvin R. Shah and Kishor H. Chikhalia
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Computer-Aided Identification of Novel DprE1 Inhibitors as Potential Anti-TB Lead Compounds: A Hybrid Virtual-Screening and Molecular Dynamics Approach
Yushir Maharaj, Soumendranath Bhakat and Mahmoud E. S. Soliman
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Identification of Pyrazole Derivative as an Antiviral Agent Against Chikungunya Through HTVS
Surender Singh Jadav, Barij Nayan Sinha, Boris Pastorino, Xavier de Lamballerie, Rolf Hilgenfeld and Venkatesan Jayaprakash
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Hybrid Pharmacophore Design and Synthesis of Naphthalimide-Benzimidazole Conjugates asPotential Anticancer Agents
Ahmed Kamal, Pogula Praveen Kumar, Mohammed Naseer Ahmed Khan, Bobburi Naga Sheshadri and Olepu Srinivas
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Synthesis of New and Known Dicoumarols in Aqueous Media: a Green and Convenient Procedure Promoted by Titanium (IV) Oxide Nanoparticles
Saeed Khodabakhshi, Mozhgan Shahamirian and Mojtaba Baghernejad
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An Improved Synthesis of (Z)-2-(5-Amino-1, 2, 4-thiadiazol-3-yl)-2- (Ethoxyimino) Acetic Acid
Songqing Wang, Yi Yao, Kai Chen, Zhujun Fang, Lexian Tong and Weihui Zhong
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An Efficient and Green Synthesis of Flavones Using Natural Organic Acids as Promoter Under Solvent-free Condition
Nitin M. Thorat, Santosh R. Kote and Shankar R. Thopate
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SYNTHESIS, BIOCHEMICAL EVALUATION AND RATIONALISATION OF A RANGE OF NOVEL THIOSEMICARBAZONE-BASED COMPOUNDS AS POTENTIALLY NEW CLASS OF DUAL INHIBITORS OF ESTRONE SULFATASE (ES) AND THE CYTOCHROME P-450 ENZYME AROMATASE (AR)
Balkrishna Bhamare, Sukriti Singh, Bhanu C. Rudra, Amit Kumar and Sabbir Ahmed
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