ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 14, 12 Issues, 2017


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Letters in Drug Design & Discovery

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Editor-in-Chief:
G. Perry
University of Texas
San Antonio, TX
USA


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Upcoming Articles (E-Pub Abstracts ahead of Print)

Ultrasound assisted-synthesis and biological evaluation of piperazinyl- prop-1-en-2-yloxy-2H-chromen-2-ones as Cytotoxic agents


Anna Pratima G. Nikalje, Shailee V. Tiwari, Jaydeep G. Tupe, Vivek K. Vyas and Gulamnizami Qureshi.


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Novel Thiazole Carboxylic Acid Derivatives Possessing a “Zinc Binding Feature” as Potential Human Glyoxalase-I Inhibitors


Qosay Ali Al-Balas, Mohammad A. Hassan, Ghazi A. Al Jabal, Nizar A. Al-Shar`i, Ammar M. Almaaytah and Tamam M Elimat.


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Ultrasound assisted faster and milder approach to 6H-pyrido[1,2-a]quinazolin-6-imine derivatives as potential inhibitors of PDE4


A. S. G. Prasad, T. Bhaskara Rao, D. Rambabu, Mandava V. Basaveswara Rao and Manojit Pal.


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Effects of Asphodeline lutea compounds on toxicity models in isolated rat microsomes and hepatocytes


Magdalena Kondeva-Burdina, Rumyana Simeonova, Vessela Vitcheva, Irina Lazarova, Reneta Gevrenova, Dimitrina Zheleva-Dimitrova, Gokhan Zengin and Nikolay D Danchev.


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Growth profile of Mycobacterium tuberculosis in the peripheral blood of BALB/c mice and efficacy of Anti-TB drugs on bacteremia


Richa Dwivedi, Shubhra Singh, Priyanka Trivedi and Vinita Chaturvedi.


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Synthesis and Anticancer Studies of Novel N-Benzyl pyridazinone Derivatives


Mohamed Elagawany, Mohamed Ibrahim, Tarek S Ibrahim, Amany M AL-Mahmoudy, Alaa Moawad, Mohammed M Ghoneim, Mohamed M Radwan and S S Panda.


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Design, synthesis and antibacterial activities of new azo-compounds: an experimental and a computational approach


Jamshaid Ashraf, Ehsan Ullah Mughal, Shahzad Murtaza, Amina Sadiq, Sheraz Ahmad Khan Tanoli, Amara Mumtaz, Abdul Hameed, Khalid Mohammed Khan, Ishtiaq Ahmed, Bilal Khalid and Asif Javid.


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Characterization and Evaluation of the Antioxidant Activity of Calamusenone, a Major Component of Hyptis pectinata (L.) Poit Essential Oil


Mairim R. Serafini, Daviane M.C. Vergne, Paula P. Menezes, João P.A. Santos, Thallita K. Rabelo, Shanmugam Saravanan, Péricles B. Alves, Emmanoel V. Costa, Hugo César R. Jesus, Marcos J. Salvador, Daniel P. Gelain, José C.F. Moreira, Ricardo F. Rocha, Adriano A.S. Araújo and Lucindo J Quintans-Júnior.


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Solvent-free mechano-chemical synthesis of new omeprazole derived metal complexes: Characterization, urease inhibitory kinetics and selective anti-Helicobacter pylori activity


Muhammad Amin, Farooq Anwar, Mahmood Anwar, Abdul Karim, Khalid M. Alkharfy and Anwarul-Hassan Gilani.


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In Vitro Evaluation of the Antibacterial Activity and Antibiotic-Modulatory Effect of Gracilaria cervicornis (Tuner) J. Agardh


Israeliane F. Cordeiro, Henrique D. M. Coutinho, João V. A. Ferreira, Lucindo José Quintans-Júnior, Irwin R. A. Menezes, Micheline A. Lima, Thiago S. Freitas, Maria Isabeli P. Gonçalo, Francisco Licaon G. Rocha, Rívio Fabrício de Figueirêdo Furtado and Jacqueline C Andrade.


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p42.3 in Gastric Carcinoma: A Novel Biomarker and Promising Therapeutic Target


Dong-Sheng Pei, Jun-Nian Zheng, Xin Ren, Fu-Chun Huo, Lu-Lu Wei and Hui Jing.


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3,4-Dihydropyrimidin-2(1H)-one C5 amides as Inhibitors of TNFα production: Synthesis, Biological Evaluation and Molecular Modeling


Ramin Miri, Omidreza Firuzi, Mohammad Hossein Ghahremani, Katayoun Javidnia, Mehdi Khoshneviszadeh and Ahmad Ebadi.


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Arginine- and Lysine-rich peptides: Synthesis, characterization and antimicrobial activity


Adriano Mollica, Giorgia Macedonio, Azzurra Stefanucci, Roberto Costante, Simone Carradori, Valentina Cataldi, Mara Di Giulio, Luigina Cellini, Romano Silvestri, Cesare Giordano, Anita Scipioni, Pasqualina Punzi and Sako Mirzaie.


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Effect Antimicrobial, Gastroprotective and Healing of Hydroalcoholic Extract of Astronium fraxinifolium


Irwin Rose Aalencar de Menezes, Lucindo José Quintas-Júnior, Anita Oliveira Brito Pereira Bezerra Martins, Brito Pereira Bezerra Martins, Cícera Datiane de Morais Oliveira, Gerlânia Oliveira Leite, Henrique Douglas Melo Coutinho, Margareth Linde Athayde, Aline Augusti Boligon, Jacqueline Cosmo Andrade, Larissa Rolim Oliveira, Marta Regina Kerntopf, Roseli Barbosa, Francisco Rafael Alves Santana Cesário and Thales Sousa Coutinho.


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Gastroprotective activity of hydroalcoholic extract of the Stryphnodendron rotundifolium Mart. in mice: mechanism actions assay


Dayanne Rakelle de Oliveira, Lucindo José Quintas-Júnior, Thaís Rodrigues de Albuquerque, Francisco Elizaudo de Brito Júnior, Cícera Norma Fernandes, Heloísa Helena Fernandes de Souza, Aline Augusti Boligon, Margareth Linde Athayde, Cicero Bezerra Felipe, Henrique Douglas Melo Coutinho, Marta Regina Kerntopf, Roseli Barbosa and Irwin Rose Aalencar de Menezes.


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Hydroxamate Inhibitor Profiling of Both Zn2+- and Ni2+-Activated Glyoxalase I Metalloenzymes Having Diverse Quaternary Structures


John F. Honek and Uthaiwan Suttisansanee.


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