ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 11, 10 Issues, 2014


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Letters in Drug Design & Discovery

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

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Upcoming Articles (E-Pub Abstracts ahead of Print)

6-Bromo-2, 3-Dioxoindolin Phenylacetamide Derivatives: Synthesis, Potent CDC25B, PTP1B inhibitors and Anticancer Activity
Shui-Lian Zhao, Zhou Peng, Xing-Hua Zhen, Yan Han, Hai-Ying Jiang, You-Le Qu and Li-Ping Guan
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FeCl3/Ultrasound mediated Reaction of 2-Aminothiophenol with Aldehydes in Water: Synthesis of 2-Substituted Benzothiazoles of Pharmacological Interest
Ponasanapalli Tirumala Venkata Ankayya Srinivas, Sallagundla Bhavani, Dandela Rambabu, Mandava Venkata Basaveswara Rao, Ravikumar Kapavarapu and Manojit Pal
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Novel Fatty Acid Analogues as Human Fatty Acid Synthase Thioesterase Domain Inhibitors: Synthesis and Their Cytotoxicity Screening
Selvaraj Jubie, Pawan Kumar Yadhav, Moola Joghee Nanjan Chandrasekar, Jeyapal Gomathi Priya, Chaitanya MVNL and Palanisamy Dhanabal
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Biological Properties of Heterocyclic Pyridinylimines and Pyridinylhydrazones
Francislene J. Martins, Rebeca Mol Lima, Juliana Alves dos Santos, Patrícia de Almeida Machado, Elaine Soares Coimbra, Adilson David da Silva and Nadia Rezende Barbosa Raposo
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First Efficient Two-Step/One-Pot Zirconium (IV)isopropoxide–Mediated Reductive Amination of Carbonyl Compounds
Cyril Pieri and Jean Michel Brunel
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Synthesis of Six Phenylalanine Derivatives and their Cell Toxicity Effect on Human Colon Cancer Cell Line HT-29
Qianyi Zhao, Ting Xu, Menghua Li, Ying Yang, Haopeng Hu, Shupei Wang, Wenjuan Yan, Ran Chen, Chunyan Zhang and Cunshuan Xu
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3D-QSAR Study of Flavone Derivatives as Inhibitors of HeLa Cervix Adenocarcinoma Cell Lines
Jae Cho, Somi Kim Cho and Yoongho Lim
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De Novo Design of High Potent DPP-IV Inhibitors Based on the Scaffold of Cyanopyrrolidine
Yu-Lei Jiang, Hao-Liang Yuan, Wei-Wei Zhang, Hai-Chun Liu, Yan-Min Zhang, Xiao Xiong, Jin-Xing Xu, Shuai Lu, Tao Lu and Ya-Dong Chen
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Pharmacophore Modeling, 3DQSAR and Structural Analysis of new Class of Potent Antimycobacterial Agents1, 3-Benzothiazin-4-Onescompounds as DprE1 Inhibitors
Ravi and S. K. Mahmood
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Biological Evaluation of Halogenated Thioureas as Cholinesterases Inhibitors against Alzheimer’s Disease & Molecular Modeling Studies
Jamshed Iqbal, Sumera Zaib, Aamer Saeed and Muhammad Muddassar
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Synthesis and Anticancer Activity of 7, 8-Dihydroxy-4-Arylcoumarins
Jianrui Wu, Ting Peng, Fang Chen, Yixin Leng, Linjiang Tong, Mengyuan Li, Rong Qu, Hua Xie, Jian Ding and Wenhu Duan
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Identification of Pyrazole Derivative as an Antiviral Agent Against Chikungunya Through HTVS
Surender Singh Jadav, Barij Nayan Sinha, Boris Pastorino, Xavier de Lamballerie, Rolf Hilgenfeld and Venkatesan Jayaprakash
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Synthesis of New and Known Dicoumarols in Aqueous Media: a Green and Convenient Procedure Promoted by Titanium (IV) Oxide Nanoparticles
Saeed Khodabakhshi, Mozhgan Shahamirian and Mojtaba Baghernejad
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An Improved Synthesis of (Z)-2-(5-Amino-1, 2, 4-thiadiazol-3-yl)-2- (Ethoxyimino) Acetic Acid
Songqing Wang, Yi Yao, Kai Chen, Zhujun Fang, Lexian Tong and Weihui Zhong
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An Efficient and Green Synthesis of Flavones Using Natural Organic Acids as Promoter Under Solvent-free Condition
Nitin M. Thorat, Santosh R. Kote and Shankar R. Thopate
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SYNTHESIS, BIOCHEMICAL EVALUATION AND RATIONALISATION OF A RANGE OF NOVEL THIOSEMICARBAZONE-BASED COMPOUNDS AS POTENTIALLY NEW CLASS OF DUAL INHIBITORS OF ESTRONE SULFATASE (ES) AND THE CYTOCHROME P-450 ENZYME AROMATASE (AR)
Balkrishna Bhamare, Sukriti Singh, Bhanu C. Rudra, Amit Kumar and Sabbir Ahmed
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