ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 23, 46 Issues, 2017


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Current Pharmaceutical Design

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  • 73rd of 253 in Pharmacology & Pharmacy

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Current: 3.052
5 - Year: 3.132

Upcoming Articles (E-Pub Abstracts ahead of Print)

Food as Pharma? The Case of Glucosinolates


Edoardo Capuano, Matthijs Dekker, Ruud Verkerk and Teresa Oliviero.


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Agaricus blazei bioactive compounds and their effects on human health: benefits and controversies


Aline Cristine da Silva de Souza, Vanesa Gesser Correa, Geferson de Almeida Gonçalves, Andréia Assunção Soares, Adelar Bracht and Rosane Marina Peralta.


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Dietary supplements: foods, medicines, or both? A controversial designation with unspecific legislation


Carla Pereira, Lillian Barros and Isabel CFR Ferreira.


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Traumatic brain injury: preclinical imaging diagnostic(s) and therapeutic approaches


Eric L. Kaijzel, Ermond R. van Beek, Marieke A. Stammes, Ivo Que, Alan B. Chan, Clemens W.G.M. Löwik and Luis J Cruz.


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Synergistic interaction between heme oxygenase (HO) and nuclear-factor E2-related factor-2 (Nrf2) against oxidative stress in cardiovascular related diseases


Joseph Fomusi Ndisang.


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Microbubbles: a novel strategy for chemotherapy


Mu-hua Luo, Chih-Kuang Yeh, Bing Situ, Jin-sui Yu, Bing-cheng Li and Zhi-yi Chen.


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Sodium-glucose cotransporter 2 inhibitors (SGLT2i): their role in cardiometabolic risk management


Niki Katsiki, Dimitri P Mikhailidis and Michael J Theodorakis.


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A New Vaccine Delivery Vehicle and Adjuvant Candidate: Bordetella Pertussis Inactivated Whole Cells Entrapped in Alginate Microspheres


Naser Mohammadpour Dounighia, Fereshteh Shahcheraghi, Mehdi Razzaghi-Abyaneh, Mojtaba Nofeli and Hossein Zolfagharian.


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Dendritic Cells Modulate Iron Homeostasis and Inflammatory Abilities Following Quercetin Exposure


Vanessa Galleggiante, Stefania De Santis, Elisabetta Cavalcanti, Aurelia Scarano, Maria De Benedictis, Grazia Serino, Maria Lucia Caruso, Mauro Mastronardi, Aldo Pinto, Pietro Campiglia, Dale Kunde, Angelo Santino and Marcello Chieppa.


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Novel Therapies Targeting Cardioprotection and Regeneration


Valeria Garrido, Evelyn Mendoza-Torres, Jaime A. Riquelme, Ariel Díaz, Marcela Pizarro, Mario Bustamante, Myra N. Chavez, María Paz Ocaranza, Rosemarie Mellado, Ramon Corbalan, Miguel L. Allende and Sergio Lavandero.


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Role of proinflammatory cytokines in dopaminergic system disturbances, implications for anhedonic features of MDD


Zihang Pan, Joshua D. Rosenblat, Walter Swardfager and Roger S McIntyre.


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BDNF/NF-kB signaling in the neurobiology of depression


Ariel Caviedes, Carlos Lafourcade, Claudio Soto and Ursula Wyneken.


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A comprehensive review of mTOR-inhibiting pharmacotherapy for the treatment of non-infectious uveitis


Joshua Blair, Robert Barry, David J Moore and Alastair K Denniston.


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Mass spectrometry imaging in nanomedicine: unraveling the potential of MSI for the detection of nanoparticles in neuroscience


Florian PY. Barré, Ron MA. Heeren and Nina Ogrinc Potočnik.


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Vegetable Organosulfur Compounds and their Health Promoting Effects


Spyridon A. Petropoulos, Francesco Di Gioia and Georgia Ntatsi.


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Smoking and Eye Pathologies. A systemic review. Part II. Retina diseases, uveitis, optic neuropathies, thyroid-associated orbitopathy.


Małgorzata Nita and Andrzej Grzybowski.


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MiRNAs: New Biomarkers and Therapeutic Targets in Dementia


Ana Teresa de Bastos Viegas, Joana Ribeiro Guedes, Ana Rafaela Oliveira, Ana Maria Sequeira Cardoso and Ana Luísa Colaço Cardoso.


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Metal nanoparticles for the treatment and diagnosis of neurodegenerative brain diseases


Valentina Vio, María José Marchant, Eyleen Araya and Marcelo J Kogan.


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Curcumin and lung cancer: the role of microRNAs


Diana Lelli, Claudio Pedone, Muhammed Majeed and Amirhosssein Sahebkar.


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Effect of Green Tea Phytochemicals on Mood and Cognition


Christina Dietz and Matthijs Dekker.


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Blood Serum Atherogenicity: Cellular Test for the Development of Anti-Atherosclerotic Therapy


Veronika A. Myasoedova, Galina A. Ivashinnikova, Igor A. Sobenin, Ekaterina A. Ivanova and Alexander N Orekhov.


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Inflammation: A novel therapeutic target/direction in atherosclerosis


Bin Li, Weihong Li, Xiaoli Li and Hong Zhou.


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Effective agents targeting the mitochondria and apoptosis to protect the heart


Eltyeb Abdelwahid, Aurimas Stulpinas and Audrone Kalvelyte.


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Nano-medicine improving the bioavailability of small molecules for the prevention of neurodegenerative diseases


Piera Di Martino, Roberta Censi, Maria Rosa Gigliobianco, Luana Zerrillo, Federico Magnoni, Dimitrios Agas, Wilma Quaglia and Giulio Lupidi.


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Phenolic compounds as nutraceuticals or functional food ingredients


Cristina Caleja, Andreia Ribeiro, Maria Filomena Barreiro and Isabel CFR Ferreira.


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Targeting nanomedicine to brain tumors: latest progress and achievements


Moniek van `t Root, Clemens Löwik and Laura Mezzanotte.


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Genetics in the Clinical Decision of Antiplatelet Treatment


Gerasimos Siasos, Marina Zaromitidou, Evangelos Oikonomou, Manolis Vavuranakis, Vicky Tsigkou, Nikolaos Papageorgiou, Dimitrios Chaniotis, Dimitrios A. Vrachatis, Christodoulos Stefanadis, Athanasios G. Papavassiliou and Dimitrios Tousoulis.


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Perspectives of in vivo Bioluminescence Imaging: Application to Basic and Translational Neuroscience


Stefanie Vogel, Franziska Collmann and Mathias Hoehn.


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Targeted Nanoparticles for the Treatment of Alzheimer’s Disease


Rafael Martín-Rapún, Laura De Matteis, Alfredo Ambrosone, Sonia García-Embid, Lucía Gutiérrez and Jesús M de la Fuente.


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Endothelial Progenitor Cells As A Therapeutic Approach For Intracerebral Hemorrhage


Juan Pías-Peleteiro, Francisco Campos, María Pérez-Mato, Esteban López-Arias, Manuel Rodríguez-Yáñez, José Castillo and Tomás Sobrino.


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Targeting the Brain with Nanomedicine


Felix Rueda and Luis J Cruz.


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The potential of nano-vehicle mediated therapy in Vasculitis and Multiple Sclerosis


Ruben V. Huis in `t Veld, Candido G. da Silva, Eric L. Kaijzel, Alan B. Chan and Luis J Cruz.


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Locomotor Training and Factors Associated with Blood Glucose Regulation after Spinal Cord Injury


Philip D. Chilibeck and Pierre A Guertin.


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The Utility of Interappendicular Connections in Bipedal Locomotion


David McMillan, Ray de Leon, Pierre A. Guertin and Dy Christine.


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Biofilm-mediated Antibiotic-resistant Oral Bacterial Infections: Mechanism and Combat Strategies


Indu Lata Kanwar, Abhishek Kumar Sah and Preeti K Suresh.


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Multilevel Analysis of Locomotion in Immature Preparations Suggests Innovative Strategies to Reactivate Stepping after Spinal Cord Injury


Michele R. Brumley, Pierre A. Guertin and Giuliano Taccola.


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Probing the Human Spinal Locomotor Circuits by Phasic Step-Induced Feedback and by Tonic Electrical and Pharmacological Neuromodulation


Ursula S. Hofstoetter, Maria Knikou, Pierre A. Guertin and Karen Minassian.


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Peri-procedural anticoagulation in catheter ablation for atrial fibrillation: a review


Dimitrios A. Vrachatis, Georgios Giannopoulos, Charalambos Kossyvakis, Vasiliki Panagopoulou, Manolis Vavuranakis, Theodore G. Papaioannou, Stamatina Pagoni, Vlasios N. Pyrgakis, Michael W. Cleman and Spyridon G Deftereos.


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Chemical Properties of Caffeic and Ferulic Acids in Biological System: Implications in Cancer Therapy. A Review


Sarah S. Damasceno, Bruna B. Dantas, Demetrius Antônio M. Araújo and José Galberto M da Costa.


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Long-circulating liposomal delivery system targeting at PDGFR-β enhances the therapeutic effect of IFN-α on hepatic fibrosis


Qinghua Li, Qi Yu, Jing Ju, Tiangeng You, Zhiqiang Yan, Xiangli Nan, Jie Zhong and Jing E Zhou.


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Potential Application of 5-Aryl-Substituted 2-Amino- benzamide Type of HDAC1/2-Selective Inhibitors to Pharmaceuticals


Shinichi Uesato, Yoshiyuki Hirata and Tsutomu Sasaki.


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Neural circuits underlying fly larval locomotion


Hiroshi Kohsaka, Pierre A. Guertin and Akinao Nose.


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Rationale for assessing safety and efficacy of drug candidates alone and in combination with medical devices: The case study of SpinalonTM


Pierre A Guertin.


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The role of antiplatelet therapy in primary prevention. A review


Lauge Østergaard, Emil L Fosbøl and Matthew T Roe.


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Antiplatelet and Anticoagulation Treatment in patients with thrombocytopenia


Nuccia Morici, Silvia Cantoni, Paola Vallerio, Marco Cattaneo and Stefano Savonitto.


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Antiplatelet agents and anticoagulants in patients with chronic kidney disease – from pathophysiology to clinical practice


Jens Lutz and Kerstin Jurk.


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Antithrombotic treatment management in patients with intracerebral hemorrhage: reversal and restart


Dimitrios Giakoumettis, George A. Alexiou, Dimitrios A. Vrachatis, Kostas Themistoklis, Pantelis Stathis, Manolis Vavuranakis and Marios S Themistocleous.


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Host-Directed Therapeutics against Mycobacterial Infections


Haruaki Tomioka, Chiaki Sano and Yutaka Tatano.


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Levamisole: A positive allosteric modulator for the α3β4 nicotinic acetylcholine receptors prevents weight gain in CD-1 mice on a high fat diet


Jeanne A. Lewis, Jerrel L. Yakel and Anshul A Pandya.


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Exosome-encapsulated microRNAs as potential circulating biomarkers in colon cancer


Mina Hosseini, Sara Khatamianfar, Seyed Mahdi Hassanian, Reza Nedaeinia, Mojtaba Shafiee, Mina Maftouh, Majid Ghayour-Mobarhan, Soudabeh Shahid Sales and Amir Avan.


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The importance of wireless capsule endoscopy for research into the intestinal absorption window of 5-aminosalicylic acid in experimental pigs


Jaroslav Kvetina, Ilja Tacheci, Milan Nobilis, Marcela Kopacova, Martin Kunes and Jan Bures.


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Bioengineered 3D Scaffolds in Cancer Research: Focus on Epithelial to Mesenchymal Transition and Drug Screening


XiaoLi Xu and LiLing Tang.


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Pharmacokinetic and Pharmacodynamic Features of Nanoemulsion Following Oral, Intravenous, Topical and Nasal Route


Hira Choudhury, Bapi Gorain, Bappaditya Chatterjee, Uttam Kumar Mandal, Pinaki Sengupta and Rakesh Kumar Tekade.


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Development of poly(lactide-co-glicolide) nanoparticles incorporating morphine hydrochloride to prolong its circulation in blood


Victoria Gómez-Murcia, Mercedes García Montalbán, Juan Carmelo Gómez-Fernández and Pilar Almela.


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Role of melatonin in body weight: A systematic review and meta-analysis


Seyed-Ali Mostafavi, Shahin Akhondzadeh, Mohammad Reza Mohammadi, Abbas-Ali Keshtkar, Saeed Hosseini, Mohammad Reza Eshraghian, Fahimeh Ahmadi, Roya Alipour and Seyed Ali Keshavarz.


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Pharmaceutical Particles Design by Membrane Emulsification: preparation methods and applications in drug delivery


Emma Piacentini, Marijana Dragosavac and Lidietta Giorno.


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Multifunctional superparamagnetic nanoparticles: from synthesis to siRNA delivery


Sanam Arami, Majid Mahdavi, Mohammad Reza Rashidi, Marziyeh Fathi, Mohammad Saeid Hejazi and Nasser Samadi.


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Optimal Pre-treatment for Acute Exposure to the Organophosphate Dicrotophos


Dietrich Ernst Lorke, Syed M. Nurulain, Mohamed Y. Hasan, Kamil Kuča and Georg A Petroianu.


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Macrocyclic Antimicrobial Peptides Engineered from ω-Conotoxin


Xinya Hemu and James Tam.


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The Role of MicroRNAs in Diagnosis, Prognosis, Metastasis and Resistant Cases in Breast Cancer


Srijit Das and Teoh Seong Lin.


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Challenges and future prospects of nanoemulsion as a drug delivery system


Megumi Nishitani Yukuyama, Edna Tomiko Myiake Kato, Raimar Löbenberg and Nadia Araci Bou-Chacra.


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Review: Application of Fused Deposition Modelling (FDM) Method of 3D Printing in Drug Delivery


Jingjunjiao Long, Hamideh Gholizadeh, Jun Lu, Craig Bunt and Ali Seyfoddin.


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Recent advances in non-invasive delivery of macromolecules using nanoparticulate carriers system


Md Shadab, Shadabul Haque, Ravi Sheshala, Lim Wei Meng, Venkata Srikanth Meka and Javed Ali.


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Introduction for Design of Nanoparticle Based Drug Delivery Systems


Edgar Chan and Hui Wang.


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Advances in Functionalized Mesoporous Silica Nanoparticles for Tumor Targeted Drug Delivery and Theranostics


Wenjia Zhang, Mengrui Liu, Anchang Liu and Guangxi Zhai.


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Role of the autonomic nervous system in the tumor micro-environment and its therapeutic potential


Zhifang Xu, Seiji Shioda, Masahisa Jinushi, Yutaka Kawakami, Hirokazu Ohtaki, Shenjun Wang, Xue Zhao, Yangyang Liu, Dan Zhou and Yi Guo.


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The roles of endoplasmic reticulum stress in the pathophysiological development of cartilage and chondrocytes


Xiaoliang Yuan, Haiqing Liu, Linfu Li, Hai Liu, Jianqiong Yang, Weimei Shi and Longhuo Wu.


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Discovery and Optimization of NAD+-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds


Fangchao Bi, Shutao Ma and Ruixin Ma.


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The Effectiveness of Topical Anti-scarring Agents and a Novel Combined Process on Cutaneous Scar Management


Qing-Qing Fang, Chun- Ye Chen, Min-Xia Zhang, Chun-Lan Huang, Xiao-Wei Wang, Ji-Hua Xu, Li-Hong Wu, Li-Yun Zhang and Wei-Qiang Tan.


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Efficacy of Ropinirole-Loaded PLGA Microspheres For The Reversion Of Rotenone-Induced Parkinsonism


Sofía Negro, Liudmilla Boeva, Karla Slowing, Ana Fernández-Carballido, Luis García-García and Emilia Barcia.


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Calixarene: A versatile material for drug design and applications


Muhammad Ajaz Hussain, Muhammad Umer Ashraf, Gulzar Muhammad, Muhammad Nawaz Tahir and Syed Nasir Abbas Bukhari.


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The role of PPARs in pathological cardiac hypertrophy and heart failure


Hai-Han Liao, Xu-Hui Jia, Huang-Jun Liu, Yang Zheng and Tang Qizhu.


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Development of a novel human scFv against EGFR L2 domain by phage display technology


Leila Rahbarnia, Safar Farajnia, Hossein Babaei, Jafar Majidi, Kamal Veisi, Shiva Ahdi Khosroshahi and Asghar Tanomand.


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