ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)

Volume 20, 42 Issues, 2014

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Current Pharmaceutical Design

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  • 62nd of 254 in Pharmacology & Pharmacy

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Upcoming Articles (E-Pub Abstracts ahead of Print)

SPARC in Tumor Pathophysiology and as a Potential Therapeutic Target
Liling Tang and Jianguo Feng
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Vitamin D3, D2 and Arterial Wall Properties in Coronary Artery Disease
Gerasimos Siasos, Dimitris Tousoulis, Evangelos Oikonomou, Konstantinos Maniatis, Stamatios Kioufis, Eleni Kokkou, Marina Zaromitidou, Eva Kassi, Antigoni Miliou and Christodoulos Stefanadis
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PET Radioligands for in Vivo Visualization of Neuroinflammation
Dieter Ory, Sofie Celen, Alfons Verbruggen and Guy Bormans
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Models And Methods In Cardiac Imaging For Metabolism Studies
M F Santarelli, N Martini, P Positano and L Landini
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Hyperpolarized Metabolic MR in the Study of Cardiac Function and Disease
M. H. Lauritzen, L. V. Sogaard, P. L. Madsen and J. H. Ardenkjaer-Larsen
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Cardiological Ultrasound Imaging
Johan M. Thijssen and Chris L. de Korte
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Imaging of Organ Metabolism in Obesity and Diabetes: Treatment Perspectives
J Hannukainen, MA Guzzardi, KA Virtanen, E Sanguinetti, P Nuutila and P Iozzo
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Treating Arterial Stiffness in Young and Elderly Patients with the Metabolic Syndrome
Konstantinos Tziomalos, Vasilios G. Athyros and Asterios Karagiannis
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New Insight into Urate-Related Mechanism of Cardiovascular Damage
Davide Grassi, Giovambattista Desideri and Claudio Ferri
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Modification of Lifestyle Factors are Needed to Improve the Metabolic Health of Patients with Cardiovascular Disease Risk
Linda Landini
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Effects of Remifentanil on the Cardiac Conduction System. Our Experience in the Study of Remifentanil Electrophysiological Properties
Brezo B. Del Blanco Narciso, Concepción Jimeno, Jesús Almendral Garrote and M Jose Anadon Baselga
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Study on Gluco-Regulatory Potential of Glimepiride Sulfonamide using in Silico, in Vitro and in Vivo Approaches
Hamendra Singh Parmar, Mahesh Kumar Bhinchar, Muskan Bhatia, Nikita Chordia, Ishan Raval, Digvijay Singh Chauhan, E. Manivannan, Rameshwar Jatwa and Anil Kumar
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Activated Immune System and Inflammation in Healthy Ageing: Relevance for Tryptophan and Neopterin Metabolism
Lucile Capuron, Simon Geisler, Katharina Kurz, Friedrich Leblhuber, Barbara Sperner-Unterweger and Dietmar Fuchs
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Pain and Obesity in the Older Adult
Robert Taylor, Joseph V. Pergolizzi, Robert B. Raffa, Srinivas Nalamachu and Philip J. Balestrieri
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Beyond Acetylcholinesterase Inhibitors for Treating Alzheimer's Disease: 7-nAChR Agonists in Human Clinical Trials
Patrizia Russo, Alessandra Del Bufalo, Alessandra Frustaci, Massimo Fini and Alfredo Cesario
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Use of Trastuzumab for Breast Cancer: the Role of Age
Walter Mazzucco, Marta Rossi, Rosanna Cusimano, Matteo Franchi, Martina Bonifazi, Alessandro Mistretta, Francesco Vitale, Walter Ricciardi, Eva Negri, Stefania Boccia and Carlo La Vecchia
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Determinants of Longevity: Genetics, Biomarkers and Therapeutic Approaches
Juulia Jylhava
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MicroRNA Therapeutics in Neurological Disease
David S. Greenberg and Hermona Soreq
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P4 Medicine Needs P4 Education
Alfredo Cesario, Charles Auffray, Patrizia Russo and Leroy Hood
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Therapeutic Application of Intrabodies Against Age-Related Neurodegenerative Disorders
Alessio Cardinale, Daniela Merlo, Paolo Giunchedi and Silvia Biocca
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Hyper-Longevity, a Late-Modern Paradigm for Understanding Longevity and Ageing in Western Developed Globalised Countries
Roberto Alzetta
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Biological Carrier Molecules of Radiopharmaceuticals for Molecular Cancer Imaging and Targeted Cancer Therapy
A Aerts, N Impens, M Gijs, M D’Huyvetter, H Vanmarcke, B Ponsard, T Lahoutte, A Luxen and S Baatout
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Metabolic Reprogramming of Human Cells in Response to Oxidative Stress: Implications in the Pathophysiology and Therapy of Mitochondrial Diseases
Yu-Ting Wu, Shi-Bei Wu and Yau-Huei Wei
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Phytoestrogens and Mitochondrial Biogenesis in Breast Cancer. Influence of Estrogen Receptors Ratio
Pilar Roca, Jorge Sastre-Serra, Mercedes Nadal-Serrano, Daniel Gabriel Pons, M del Mar Blanquer-Rossello and Jordi Oliver
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Mitochondrial Biogenesis: Regulation By Endogenous Gases during Inflammation and Organ Stress
Hagir B. Suliman and Claude A. Piantadosi
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Mitochondrial Biogenesis in Health and Disease. Molecular and Therapeutic Approaches
Sanchis-Gomar Fabian, García Giménez, José Luis, Gómez Cabrera, Mari Carmen and V Federico Pallardo
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Healthspan and Longevity in Mammals: A Family Game for Cellular Organelles?
Enzo Nisoli and Alessandra Valerio
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Regulation And Quantification Of Cellular Mitochondrial Morphology And Content
Karl J. Tronstad, Marco Nooteboom, Linn I. H. Nilsson, Julie Nikolaisen, Maciek Sokolewicz, Sander Grefte, Ina K.N. Pettersen, Sissel Dyrstad, Fredrik Hoel, Peter H.G.M. Willems and Werner J.H. Koopman
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Mitochondria: Prospective Targets for Neuroprotection in Parkinson’s Disease
Anuradha Yadav, Swati Agrawal, Shashi Kant Tiwari and Rajnish K. Chaturvedi
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Editorial : Targeting vascular calcification: Up-date
Yuri V Bobryshev
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Mechanisms of Medial Arterial Calcification in Diabetes
Dimitry A. Chistiakov, Igor A. Sobenin, Alexander N. Orekhov and Yuri V. Bobryshev
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Mechanisms of Vascular Calcification and Associated Diseases
Juliana Marulanda, Saleh Alqarni and Monzur Murshed
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New Therapeutic Approaches to Arterial Calcification Via Inhibition of Transglutaminase and B-Catenin Signaling
Mikhail Konoplyannikov and Maria Nurminskaya
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Abdominal Aortic Calcification: Clinical Significance, Mechanisms and Therapies
Jonathan Golledge
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Vascular Calcification in Chronic Kidney Disease: Role of Disordered Mineral Metabolism
Shyamal Palit and Jessica Kendrick
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Blood Serum Atherogenicity and Coronary Artery Calcification
Igor A. Sobenin, Veronica A. Myasoedova, Elena V. Anisimova, Xenia N. Pavlova, Stefan Möhlenkamp, Axel Schmermund, Rainer Seibel, Sina Berenbein, Nils Lehmann, Susanne Moebus, Jöckel Karl-Heinz, Alexander N. Orekhov and Raimund Erbel
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Circulating Cellular Players in Vascular Calcification
Mattia Albiero, Angelo Avogaro and Gian Paolo Fadini
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Editorial : Novel Insights into the Role of Anesthetics and Opioids in Organ or Tissue Protection
Hiroyuki Kinoshita
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Mechanistic View of Renal Protective Action of Calcium Channel Blockade
N Sugano
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Genistein Inhibits Cell Growth and Invasion Through Regulation of MiR-27a in Pancreatic Cancer Cells
Jun Xia, Long Cheng, Chuanzhong Mei, Jia Ma, Ying Shi, Fanpeng Zeng, Zhenghuan Wang and Zhiwei Wang
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MicroRNAs (miRNA) as Biomarker(s) for Prognosis and Diagnosis of Gastrointestinal (GI) Cancers
Muzafar A. Macha, Parthasarathy Seshacharyulu, Shiv Ram Krishn, Priya Pai, Satyanarayana Rachagani, Maneesh Jain and Surinder K. Batra
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Oncogenic MicroRNAs in the Genesis of Leukemia and Lymphoma
Yanyan Pan, Mei Meng, Gaochuan Zhang, Hongyan Han and Quansheng Zhou
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MicroRNAs in Cancer Stem Cells: New Regulators of Stemness
Fei Xing, Kerui Wu and Kounosuke Watabe
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MicroRNAs in Breast Cancer Therapy
Joy Tang, Aamir Ahmad and Fazlul H. Sarkar
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MiRNAs in Human Cancers: The Diagnostic and Therapeutic Implications
Qiong Wu, Zhiping Yang, Yongquan Shi and Daiming Fan
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The miRNAs and Epithelial-Mesenchymal Transition in Cancers
Lin Ching-Wen, Kao Shih-Han and Yang Pan-Chyr
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Arsenic Trioxide Targets miR-125b in Glioma Cells
Sulian Chen, Lihua Zhu, Jing Huang, Ying Cai, Xiaohui Lu, Qingling Yang, Qiong Wu, Changjie Chen and Zhiwei Wang
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Regulation of KRAS–PAK4 Axis by MicroRNAs in Cancer
Zeshan S. Choudhry, Vraj Tripathi, Mike Sutton, Bin Bao, Ramzi M. Mohammad and Asfar S. Azmi
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Assessing Schizophrenia-Relevant Cognitive and Social Deficits in Mice: a Selection of Mouse Behavioral Tasks and Potential Therapeutic Compounds
Wen-Sung Lai, Chia-Yuan Chang, Wan-Rong Wong, Ju-Chun Pei, Ya-Shan Chen and Wei-li Hong
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Frontal Lobe Synaptic Plasticity in Development and Disease: Modulation by the Dopamine D1 Receptor
Lynn D. Selemon
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The Co-Agonist Site of NMDA-Glutamate Receptors: a Novel Therapeutic Target for Age-Related Cognitive Decline
Rogério Panizzutti, Linda Scoriels and Marcos Avellar
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NMDA Neurotransmission Dysfunction in Mild Cognitive Impairment and Alzheimer’s Disease
Chieh-Hsin Lin, Yu-Jhen Huang, Hsien-Yuan Lane and Guochuan E. Tsai
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Predicting Protein-Ligand Interactions Based on Chemical Preference Features with its Application to New D-Amino Acid Oxidase Inhibitor Discovery
Mingzhu Zhao, Hao-Teng Chang, Qiang Zhou, Tao Zeng, Zhi-Ping Liu, Luonan Chen and Dong-Qing Wei
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Inhibitory Effects of Water Caltrop Pericarps on the Growth of Human Gastric Cancer Cells In Vitro
Qiusheng Lin, Junhui Shen, Ying Ning, Shengrong Shen and Undurti N. Das
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Editorial: From gut inflammation to gastrointestinal disorders Current update on pathophysiology, molecular mechanism and pharmacological treatment modalities
Predrag Sikiric
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Manifestations In Course Of Celiac Disease: Case Report And Review Of The Literature
Skroza Nevena, Proietti Ilaria, Bernardini Nicoletta, La Viola Giorgio, Mancini Maria Teresa, Nicolucci Francesca, Pampena Riccardo, Tolino Ersilia, Zuber Sara and Potenza Concetta
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Helicobacter pylori eradication therapy: advantages and disadvantages
Justyna Bien, Maria Bozko, Nisar P. Malek and Przemyslaw Bozko
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EDITORIAL:The Multidomain Mobility Lab in Older Persons: From Bench to Bedside
Marcello Maggio, Gian Paolo Ceda and Fulvio Lauretani
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Role of brain NUCB2/nesfatin-1 in the regulation of food intake
Andreas Stengel and Yvette Taché
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Regulation of Gastric Nesfatin-1/NUCB2
Ziru Li, Michael Mulholland and Weizhen Zhang
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Discovery of Nesfatin-1 and Overview of Biological Actions and New Developments
Masatomo Mori, Masanobu Yamada, Shuichi Okada, Koshi Hashimoto, Tesurou Satoh, Hiroyuki Shimizu and Toshihiko Yada
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Role of NUCB2/nesfatin-1 in glucose control: diverse functions in islets, adipocytes and brain
Masanori Nakata and Toshihiko Yada
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Central and peripheral expression and distribution of NUCB2/nesfatin-1
Miriam Goebel-Stengel and Lixin Wang
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Role of NUCB2/nesfatin–1 as a possible biomarker
Suleyman Aydin
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Editorial: Rational Design of Antiviral Compounds
Vladimir Frecer and Stanislav Miertus
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EDITORIAL Advances in Computational Structure Based Drug Discovery
Gergely Tóth
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Editorial Cardio-Metabolic Complications: Current Perspective and Future Developments.
Joseph Fomusi Ndisang
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EDITORAL Novel strategies for cardiac repair post-myocardial infarction
Simeon Agathopoulos and Theofilos M. Kolettis
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Sagnik Bhattacharyya
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Dietary Interventions for Atopic Disorders
Despoina Mavrommati and Theoharis C. Theoharides
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Editorial Leptin and the cardiovascular system – a target for therapeutic interventions
Jerzy Bełtowski
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EDITORIAL Structure-based Drug Design: Strategies and Challenges
Guang-Fu Yang
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