ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)

Volume 21, 38 Issues, 2014

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Current Medicinal Chemistry

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 5th of 59 in Chemistry & Medicinal
  • 41st of 261 in Pharmacology & Pharmacy
  • 80th of 290 in Biochemistry & Molecular Biology

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Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge

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Current: 4.07
5 - Year: 4.471

Upcoming Articles (E-Pub Abstracts ahead of Print)

Intracranial Aneurysms; in Need of Early Diagnostic and Treatment using Bio- and Nanotechnology
Shima Salmasi and Alexander Marcus Seifalian
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Intracranial Stents Past, Present and the Future Trend: Stents Made with Nano-particle or Nanocomposite Biomaterials
Junjie Zhao, Deepak Kalaskar, Yasmin Farhatnia, Xiaoxin Bai, Peter E. Bulter and Alexander M. Seifalian
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Nose-to-Brain Drug Delivery by Nanoparticles in the Treatment of Neurological Disorders
Wei-Yi Ong, Shalini Suku Maran and Luca Costantino
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Challenges in the Design of Clinically Useful Brain-Targeted Drug Nanocarriers
Luca Costantino, Diana Boraschi and Mike Eaton
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Nanomedicine and its Application in Treatment of Microglia-Mediated Neuroinflammation
Nimmi Baby, Radhika Patnala, Eng-Ang Ling and S. ThameemDheen
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Engineered nanomaterials and the Nervous System: An Update
Myrtill Simko and Mats-Olof Mattsson
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Nanotechnology and Alzheimer’s Disease: What Has Been Done and What to Do
B. Ruozi, D. Belletti, F. Pederzoli, P. Veratti, F. Forni, M. A. Vandelli and G. Tosi
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Nanomedicine Based Nanoparticles for Neurological Disorders
Bhasker Sriramoju, Rupinder K. Kanwar and Jagat R. Kanwar
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Accessing Targeted Nanoparticles to the Brain: The Vascular Route
Annette Burkhart, Mihnaz Azizi, Maj Schneider Thomsen, Louiza Bohn Thomsen and Torben Moos
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General Aspects of Metal Toxicity
Henryk Kozlowski, Paulina Kolkowska, Joanna Watly, Karolina Krzywoszynska and Slawomir Potocki
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Interaction of Chemokines with their Receptors – From initial Chemokine Binding to Receptor Activating Steps
Stefanie Thiele and Mette Marie Rosenkilde
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Nanoparticles in Melanoma
M. A. Berciano-Guerrero, A. Montesa-Pino, G. Castaneda-Penalvo, L. Munoz-Fernandez and J. Rodriguez-Flores
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A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy
Xiaoxuan Xu, L i Xiao, Ping Xiao, Shikun Yang, Fuyou Liu, Yashpal Y Kanwar and Lin Sun
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Effects of Tetrahydrohyperforin in Mouse Hippocampal Slices: Neuroprotection, Long-term Potentiation and TRPC Channels
Carla Montecinos-Oliva, Andreas Schüller, Jorge Parodi, Francisco Melo and Nibaldo C. Inestrosa
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Perspectives on Tuberculosis Pathogenesis and Discovery of Anti-Tubercular Drugs
Fidele Ntie-Kang, Joseph N. Yong, Luc C Owono Owono, Wolfgang Sippl and Eugene Megnassan
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Computational Approaches for the Identification and Optimization of Src Family Kinases Inhibitors
Giulio Poli, Adriano Martinelli and Tiziano Tuccinardi
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Iron Chelating Strategies in Systemic Metal Overload, Neurodegeneration and Cancer
Elzbieta Gumienna-Kontecka, Monika Pyrkosz-Bulska, Agnieszka Szebesczyk and Malgorzata Oledzka
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Hydrogen Sulfide and Endothelial Dysfunction: Relationship with Nitric Oxide
Zaid Altaany, Francesco Moccia, Luca Munaron, Daniele Mancardi and Rui Wang
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Endothelial dysfunction: The link between homocysteine and hydrogen sulfide
Sathnur B Pushpakumar, Sourav Kundu and Utpal Sen
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Endothelial Dysfunction in Metabolic Diseases: Role of Oxidation and Possible Therapeutic Employment of N Acetylcysteine
Andi Masha and Valentino Martina
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Chelating Agents for the Sequestration of Mercury(II) and Monomethyl Mercury(II)
Francesco Crea, Concetta De Stefano, Claudia Foti, Demetrio Milea and Silvio Sammartano
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GABA System as a Target for New Drugs
Paula Kowalczyk and Katarzyna Kulig
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DNA Binding Mode of Transition Metal Complexes, a Relationship to Tumor Cell Toxicity
Muhammad Ashfaq, Tayyaba Najam, Syed Shoaib Ahmad Shah, Muhammad Mahboob Baniahmad, Salma Shaheen, Rukhsana Tabassum and Gildardo Rivera
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Novel in Situ Activity Assays for the Quantitative Molecular Analysis of Neurodegenerative Processes in the Retina
P.A.R. Ekström, M. Ueffing, E. Zrenner and F Paquet-Durand
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BoronicAcid-based Enzyme Inhibitors: A Review of Recent Progress
W u Zhongyu, Hao Fang and X u Wenfang
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Salvianolic Acid B Inhibits Atherogenesis of Vascular Cells through Induction of Nrf2-Dependent Heme Oxygenase-1
Hyun Jung Lee, MiRan Seo and Eun Jig Lee
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Oxidative Stress, Redox Signaling and Cancer Chemoresistance: Putting Together the Pieces of the Puzzle
Vanessa Jacob Victorino, Luciana Pizzatti, Pamela Michelletti and Carolina Panis
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Novel Nor-Homo- and Spiro-Oxetan- Steroids Target the Human Androgen Receptor and Act as Antiandrogens
Marie Thiele, Sebastian Rabe, Wiebke Hessenkemper, Daniela Roell, Sophie Bartsch, Florian Kraft, Tsion E. Abraham, Adriaan B. Houtsmuller, Martin E. van Royen, Athanassios Giannis and Aria Baniahmad
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Fetal Programming of the Human Brain: is there a Link with Insurgence of Neurodegenerative Disorders in Adulthood?
G Faa, M A. Marcialis, A Ravarino, M Piras, M C Pintus and V Fanos
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Effects of Iron and Copper Overload on the Human Liver: an Ultrastructural Study
D Fanni, V Fanos, C Gerosa, M Piras, A Dessì, A Atzei, P Van Eyken, Y Gibo and G Faa
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Potential Therapeutic Drugs and Methods for the Treatment of Amyotrophic Lateral Sclerosis
Gladys Yacila and Youssef Sari
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Toxicity of Nanoparticles
Maria Antonietta Zoroddu, Serenella Medici, Alessia Ledda, Valeria Marina Nurchi, Joanna I. Lachowicz and Massimiliano Peana
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Copper Chelators: Chemical Properties and Biomedical Applications
Matteo Tegoni, Daniela Valensin, Leonardo Toso and Maurizio Remelli
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Cell To Cell Spreading Of Misfolded Proteins As A Therapeutic Target In Motor Neuron Disease
Livia Pasquali, Paola Lenzi, Francesca Biagioni, Gabriele Siciliano and Francesco Fornai
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bHLHTranscription Factors Inhibitors For Cancer Therapy: General Features For InSilico Drug Design
Igor F. Tsigelny, Valentina L. Kouznetsova, Sandeep C. Pingle and Santosh Kesari
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Targeting Platinum Resistant Disease in Ovarian Cancer
Stefanie L. Morgan, Jamie E. Medina, Matthew M. Taylor and Daniela M. Dinulescu
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Mechanism of Cancer Drug Resistance and the Involvement of Noncoding RNAs
Hongping Xia and Kam M. Hui
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Four Major Factors Regulate Phosphatidylinositol 3-Kinasesignaling Pathwayin Cancers Induced by Infection of Human Papillomaviruses
Wu Jianhong, Jiezhong Chen, Lifang Zhang, Paul P. Masci and Kong-Nan Zhao
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HIF-1 Signaling in Drug Resistance to Chemotherapy
Noel A. Warfel and Wafik S. El-Deiry
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IL-6 Activated JAK/STAT3 Pathway and Sensitivity to Hsp90 Inhibitors in Multiple Myeloma
Iryna Kolosenko, Dan Grandér and Katja Pokrovskaja Tamm
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Targeting Drug-Resistant Prostate Cancer with Dual PI3K/MTOR Inhibition
Kai Dun Tang and Ling Ming-Tat
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Nanostructured Biomaterials with Antimicrobial Properties
Yesim Muge Sahin, Mehmet Yetmez, Faik N. Oktar, O. Gunduz, Simeon Agathopoulos, Ecaterina Andronescu, Denisa Ficai, Maria Sonmez and Anton Ficai
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Biomedical Applications of Synthetic, Biodegradable Polymers for the Development of Anti-Infective Strategies
Serban Bertesteanu, Mariana Carmen Chifiriuc, Alexandru Mihai Grumezescu, Ατηanasia G. Printza, Thill Marie-Paule, Valentina Grumezescu, Vlad Mihaela, Veronica Lazar and Raluca Grigore
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New Molecular Strategies for Reducing Implantable Medical Devices Associated Infections
Alina Maria Holban, Monica Cartelle Gestal and Alexandru Mihai Grumezescu
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Methods for Synthesizing the Macromolecular Components of Smart Nanosized Carriers for Controlled Drug Delivery
Paul Cătălin Balaure and Alexandru Mihai Grumezescu
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Advances in Bio-Hybrid Nanostructures with Anti-Pathogenic Activity
Keng-Shiang Huang, Shu-Chen Chang, Chih-Hui Yang and Chih-Yu Wang
View Abstract
Antimicrobial Applications of Water-Dispersible Magnetic Nanoparticles in Biomedicine
Keng-Shiang Huang, Dar-Bin Shieh, Chen-Sheng Yeh, Ping-Ching Wu and Fong-Yu Cheng
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Editorial: Prevention of Microbial Biofilms - the Contribution of Micro and Nanostructured Materials
Alexandru Mihai Grumezescu and Carmen Mariana Chifiriuc
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Perinatal Heart Programming: Long-Term Consequences
A. Faa, R. Ambu, G. Faa and V. Fanos
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Antihypertensive Therapy in Children: Differences in Medical Approach Between the United States and Europe
P. P. Bassareo, V. Bassareo, N. Iacovidou and G. Mercuro
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Editorial: Cardiovascular Drug Therapy in Paediatric Age: from Metabolomics to Clinical Practice
P. P. Bassareo and V. Fanos
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Tumor Antigen-Derived Peptides Delivery for Cancer Immunotherapy
Ma Wenxue
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Interaction of Crotamine and Protamine, Small Cationic Peptides, With The Retinal Spreading Depression
EmptyYN="Y" Fernandes de Lima V M, P Spencer and W Hanke
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Editorial: Current status and progress of radiopharmaceuticals for molecular imaging and targeted therapy
Junbo Zhang
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On the Physiological Role of Cytosolic 5’-Nucleotidase II (Cn-II): Pathological and Therapeutical Implications
Maria Grazia Tozzi, Rossana Pesi and Simone Allegrini
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The role of soluble 5`-nucleotidases in the conversion of nucleotide analogs. Metabolic and therapeutic aspects
Andrzej C Składanowski
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The Enzymology of Cytosolic Pyrimidine 5’-Nucleotidases: Functional Analysis and Physiopathological Implications
Giulio Magni, Adolfo Amici and Giuseppe Orsomando
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5'-Nucleotidases, Nucleosides and their Distribution in the Brain: Pathological and Therapeutic Implications
Zsolt Kovács, Árpád Dobolyi, Katalin A. Kékesi and Gábor Juhász
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Therapeutic Perspectives for CN-II in Cancer
Lars Petter Jordheim
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Enzymatic Properties and Physiological Roles of Cytosolic 5’-Nucleotidase II
Roichi Itoh
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Is The Expression Of Deoxynucleoside Kinases And 5´-Nucleotidases In Animal Tissues Related To The Biological Effects Of Nucleoside Analogs?
Staffan Eriksson
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Editorial “ Metabolic, pathological, and therapeutic perspectives intracellular 5’-nucleotidases”
Piero Luigi Ipata
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Metal complexes of biologically active ligands as potential antioxidants
Irena Kostova, Stefan Balkansky and Stefan Balkansky
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System models, assays, and endpoint parameters to evaluate anticancer compounds during preclinical screening
Juan Sebastian Yakisich
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