ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)


Volume 17, 16 Issues, 2016


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Current Drug Targets

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  • 77th of 254 in Pharmacology & Pharmacy

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Editor-in-Chief:
Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA


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Current: 3.021
5 - Year: 3.260

Upcoming Articles (E-Pub Abstracts ahead of Print)

Molecular targets and angiogenesis in renal cell carcinoma, a multi-target approach: mini review


Simone A.M. Badal, William D. Aiken and Sheray N Chin.


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SMALL-CELL LUNG CANCER: CLINICAL MANAGEMENT AND UNMET NEEDS, New perspectives for an old problem


Giuseppe Lo Russo, Marianna Macerelli, Marco Platania, Nicoletta Zilembo, Milena Vitali, Diego Signorelli, Claudia Proto, Monica Ganzinelli, Rosaria Gallucci, Francesco Agustoni, Gianpiero Fasola, Filippo de Braud and Marina Chiara Garassino.


View Abstract


Mechanism and potential inhibitors of GlmU: a novel target for antimicrobial drug discovery


Rashmi Sharma and Inshad Ali Khan.


View Abstract


Antiangiogenics and Hypoxic Response: Role of Fatty Acid Synthase Inhibitors


Maria Bueno, Jesus Sanchez, Ramon Colomer and Miguel Quintela-Fandino.


View Abstract


Strategies Targeting DNA Topoisomerase I in Cancer Chemotherapy: Camptothecins, Nanocarriers for Camptothecins, Organic Non-Camptothecin Compounds and Metal Complexes


Kurtulus Gokduman.


View Abstract


The molecular concept of atheromatous plaques


Zar Chi Thent, Chiranjib Chakraborty, Pasuk Mahakkanukrauh, Nik Kosai, Reynu Rajan and Srijit Das.


View Abstract


Future targets in endothelial biology: Endothelial cell to mesenchymal transition


Pei-Yu Chen and Michael Simons.


View Abstract


Chemical modifications and biological activities of polysaccharides


Gangliang Huang, Hualiang Huang and Xin Chen.


View Abstract


The benefits and side effects of bevacizumab for the treatment of recurrent ovarian cancer


Wenwen Zhang, Zhaojun Shen, Hui Luo, Xiaoli Hu, Lihong Zheng and Xueqiong Zhu.


View Abstract


The Roles of Sox Family Genes in Sarcoma


Jingyuan Li, Jacson Shen, Kunzheng Wang, Francis Hornicek and Zhenfeng Duan.


View Abstract


Long-term issues after Immunosuppressive therapy for Aplastic Anemia:


Flore Sicre de Fontebrune and Gerard Socié.


View Abstract


MicroRNAs as Potential Targets for Treatment of Osteoclast-Related Diseases


Haowei Li, Zanjing Zhai, Xinhua Qu, Jiake Xu, An Qin and Kerong Dai.


View Abstract


Editorial: Embryonic signaling pathways as potential targets for the treatment of rhabdomyosarcoma


Soledad Gallego and Josep Roma.


View Abstract


Rational Design of Multi-Target Estrogen Receptors ERα and ERβ by QSAR Approaches


Qi Zhao, Yuxi Lu, Yan Zhao, Rongchao Li, Feng Luan and M Natália D S Cordeiro.


View Abstract


Modelling chemotherapy-induced cardiotoxicity by human pluripotent stem cells


Rosalinda Madonna, Christian Cadeddu, Martino Deidda, Paolo Spallarossa, Concetta Zito and Giuseppe Mercuro.


View Abstract


The Role of MicroRNA in Pathogenesis and as Markers of HCV Chronic Infection


Chang Ho Lee, Ji Hyun Kim and Seong-Wook Lee.


View Abstract


Smart triggered release in controlled drug delivery


Paul Cătălin Balaure, Dragos Gudovan and Iulia Alexandra Gudovan.


View Abstract


Phytometabolites Targeting Warburg Effect in Cancer Cells: A Mechanistic Review


Mohadeseh Hasanpourghadi, Chung Yeng Looi, Ashok Kumar Pandurangan, Gautam Sethi, Won Fen Wong and Mohd Rais Mustafa.


View Abstract


Smart Drug Delivery Systems in Cancer Therapy


Gozde UNSOY and Ufuk GUNDUZ.


View Abstract


Nosocomial infections and antimicrobial treatment in coiled patients with aneurysmal subarachnoid hemorrhage


Peter Lackner, Christoph Mueller, Ronny Beer, Gregor Broessner, Marlene Fischer, Raimund Helbok, Alois Schiefecker, Erich Schmutzhard and Bettina Pfausler.


View Abstract


Recent Advances in Nanosystems and Strategies for Managing Leishmaniasis


Rudra Vaghela, Parthasarathi K. Kulkarni, Riyaz Ali M. Osmani, Rohit R. Bhosale and V Naga Sravan Kumar Varma.


View Abstract


The role of statins in heme oxygenase-1 activation in cardiovascular diseases


A. Piechota-Polanczyk and A Jozkowicz.


View Abstract


Advances in Drug Delivery Systems, from 0 to 3D superstructures


Marius RADULESCU, Simona Popescu, Denisa FICAI, Maria SONMEZ, Ovidiu OPREA, Angela SPOIALĂ, Anton FICAI and Ecaterina ANDRONESCU.


View Abstract


Oxidative stress and antioxidants in neurological diseases: is there still hope?


Andreia Neves Carvalho, Omidreza Firuzi, Maria João Gama, Jack van Horssen and Luciano Saso.


View Abstract


Natural small molecules as stabilizers and activators of cancer-associated NQO1 polymorphisms


AL Pey, CF Megarity, E Medina-Carmona and DJ Timson.


View Abstract


Structural and functional aspects of class A carbapenemases


Thierry Naas, Laurent Dortet and Bogdan I Iorga.


View Abstract


Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer


Nand Kishor Roy, Devivasha Bordoloi, Javadi Monisha, Ganesan Padmavathi, Devivasha Bordoloi, Javadi Monisha, Ganesan Padmavathi, Jibon Kotoky, Ramesh Golla and Ajaikumar B Kunnumakkara.


View Abstract


Antiangiogenic resistance and cancer metabolism: opportunities for synthetic lethality


Simon Lord, Juan M. Funes, Adrian L Harris and Miguel Quintela-Fandino.


View Abstract


Pharmacoperones as a New Therapeutic Approach: In vitro Identification and In vivo Validation of Bioactive Molecules


Alfredo Ulloa-Aguirre and P Michael Conn.


View Abstract


Tumor Stroma Manipulation By MSC


Giulia Grisendi, Carlotta Spano, Filippo Rossignoli, Naomi D'souza, Giulia Golinelli, Agnese Fiori, Edwin M Horwitz, Valentina Guarneri, Federico Piacentini, Paolo Paolucci and Massimo Dominici.


View Abstract


Targeting Cystathionine Beta-Synthase Misfolding in Homocystinuria by Small Ligands: State of the Art and Future Directions


Tomas Majtan, Angel L. Pey, June Ereño-Orbea, Luis Alfonso Martínez-Cruz and Jan P Kraus.


View Abstract


Antiangiogenic resistance: Novel angiogenesis axes uncovered by antiangiogenic therapies research


Gabriela Jiménez-Valerio and Oriol Casanovas.


View Abstract


MicroRNAs as Candidate Drug Targets for Cardiovascular Diseases


Pengzhou Hang, Jing Guo, Chuan Sun and Zhimin Du.


View Abstract


Polypharmacology of approved anticancer drugs


Ivano Amelio, Andrey Lisitsa, Richard A. Knight, Gerry Melino and Alexey V Antonov.


View Abstract


Elastin-like recombinamers as smart drug delivery systems


F. Javier Arias, Mercedes Santos, Arturo Ibáñez-Fonseca, Jesús Piña and Sofía Serrano.


View Abstract


Soft Computing Techniques for the Protein Folding Problem on High Performance Computing Architectures.


Antonio Llanes, Andrés Muñoz, Andrés Bueno-Crespo, Teresa García-Valverde, Antonia Sánchez, Francisco Arcas-Túnez, Horacio Pérez-Sánchez and José M Cecilia.


View Abstract


Adoptive Immunotherapy for Leukemia with Ex Vivo Expanded T Cells.


CR Cruz and CM Bollard.


View Abstract


Rationale and Prospects of Targeting Bacterial Two-component Systems for Antibacterial Treatment of Cystic Fibrosis Patients


Nadya Velikova and Jerry M Wellsa.


View Abstract


Functionalized magnetic nanostructures for anticancer therapy


Eugenia Dumitra Teodor, Florentina Gatea, Anton Ficai and Gabriel Lucian Radu.


View Abstract


Recent Advancement and Technological Aspects of Pulsatile Drug Delivery System - A Laconic Review


Vinay Pandit, Ajay Kumar, M.S Ashawat, C.P. Verma and Pravin Kumar.


View Abstract


STIMULI-RESPONSIVE SMART LIPOSOMES IN CANCER TARGETING


Ankit Jain and Sanjay K Jain.


View Abstract


Drug Target Validation Methods in Malaria - Protein Interference Assay (PIA) as a Tool for Highly Specific Drug Target Validation


Kamila A. Meissner, Sergey Lunev, Yuan-Ze Wang, Marleen Linzke, Fernando de Assis Batista, Carsten Wrenger and Matthew R Groves.


View Abstract


Immunotherapy and hormone-therapy in metastatic breast cancer: a review and an update


Andrea Nicolini, Angelo Carpi, Paola Ferrari, Pier Mario Biava and Giuseppe Rossi.


View Abstract


Can microRNAs Be Biomarkers or Targets for Therapy of Ischemic Coronary Artery Disease in Metabolic Syndrome?


Petra Rocic.


View Abstract


Role of interferons in chronic hepatitis C infection


Carolina Scagnolari, Katia Monteleone, Giulia Cacciotti and Guido Antonelli.


View Abstract


Nuclear Factor Kappa B: A Potential Target to Persecute Head and Neck Cancer


Javadi Monisha, Nand Kishor Roy, Devivasha Bordoloi, Amit Kumar, Ramesh Golla, Jibon Kotoky, Ganesan Padmavathi and Ajaikumar B Kunnumakkara.


View Abstract


Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release after Spontaneous Subarachnoid Hemorrhage


Alois Josef Schiefecker, Anelia Dietmann, Ronny Beer, Bettina Pfausler, Peter Lackner, Mario Kofler, Marlene Fischer, Gregor Broessner, Florian Sohm, Miriam Mulino, Claudius Thomé, Christian Humpel, Erich Schmutzhard and Raimund Helbok.


View Abstract


Biophysical Screening for Identifying Pharmacological Chaperones and Inhibitors against Conformational and Infectious Diseases


A. Velazquez-Campoy, J. Sancho, O. Abian and S Vega.


View Abstract


Portals and Web-based Resources for Virtual Screening


Jens Krüger, Philipp Thiel, Ivan Merelli, Richard Grunzke and Sandra Gesing.


View Abstract


Review of the Third Domain Receptor Binding Fragment of Alpha-fetoprotein (AFP): Plausible Binding of AFP to Lysophospholipid Receptor Targets


GJ Mizejewski.


View Abstract


“Mechanism of Action: How Nano-antimicrobials Act?”


Bushra Jamil, Habib Bokhari and Muhammad Imran.


View Abstract


Characterization and Management of Cutaneous Side Effects Related to the Immunosuppressive Treatment in Solid Organ Recipients.


Paola Savoia, Andrea Ranghino and Paolo Fava.


View Abstract


Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents


R Colomer, A Sarrats, R Lupu and T Puig.


View Abstract


Structure-based drug discovery accelerated by many-core devices


Wei Feinstein and Michal Brylinski.


View Abstract


Recent advances on protein-protein docking


Qian Zhang, Ting Feng, Lei Xu, Huiyong Sun, Peichen Pan, Youyong Li, Dan Li and Tingjun Hou.


View Abstract


Computer aided drug design for multi-target drug design: SAR /QSAR, molecular docking and pharmacophore methods


Jahan Ghasemi and Azizeh Abdolmaleki.


View Abstract


Astrocytes: adhesion molecules and immunomodulation


Shane Liddelow and Daniel Hoyer.


View Abstract


The challenges of modeling drug resistance to antiangiogenic therapy


Michalis Mastri, Spencer Rosario, Amanda Tracz, Robin E. Frink, Rolf A. Brekken and John M L Ebos.


View Abstract


Targeting MET receptor in rhabdomyosarcoma: rationale and progress


Barbara Szewczyk, Klaudia Skrzypek and Marcin Majka.


View Abstract


Diabetes and Complications: Cellular Signalling Pathways, Current Understanding and Targeted Therapies


Krishna A. Adeshara, Arundhati G. Diwan and Rashmi S Tupe.


View Abstract


Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: a Systematic Review


Yuanchao Xie, Xiangrui Jiang, Jianfeng Li and Jingshan Shen.


View Abstract


HPC analysis of multiple binding sites communication and allosteric modulations in drug design: the HSP case study


Federica Chiappori, Luciano Milanesi and Ivan Merelli.


View Abstract


A Perspective on Monoamine Oxidase Enzyme as Drug Target: Challenges and Opportunities


Bhupinder Kumar, Vivek Prakash Gupta and Vinod Kumar.


View Abstract


LncRNA HOTAIR as prognostic circulating marker and potential therapeutic target in patients with tumor diseases.


Gerardo Botti, Laura Marra, Maria Gabriella Malzone, Annamaria Anniciello, Chiara Botti, Renato Franco and Monica Cantile.


View Abstract


The double roles of the prostaglandin E2 EP2 receptor in intracerebral hemorrhage


Xu Luo, Qiquan Zhu, Jie Zhang, Qin Huang, Zongyi Xie and Yuan Cheng.


View Abstract


Dysregulated Chemokine Signaling in Cystic Fibrosis Lung Disease: A Potential Therapeutic Target


Xiaoqing Guan, Yuning Hou, Fei Sun, Zhe Yang and Chunying Li.


View Abstract


Targeting Transient Receptor Potential Canonical Channels for Nervous System Diseases


Yibin Wang, Jiyuan Bu, Haitao Shen, Haiying Li, Zhong Wang and Gang Chen.


View Abstract


Design of lipophilic prodrugs to improve drug delivery and efficacy


Abhirup Mandal, Mitesh Patel, Ye Sheng and Ashim K Mitra.


View Abstract


Proteinase-activated receptor 2: Are common functions in glial and immune cells linked to inflammation-related CNS disorders?


Trevor J. Bushell, Margaret R. Cunningham, Kathryn A. McIntosh, Serge Moudio and Robin Plevin.


View Abstract


Vascular Biology Center Medical College of Georgia Georgia Regents University Augusta, GA, USA


Rodolfo Montironi, Matteo Santoni, Liang Cheng, Antonio Lopez-Beltran, Francesco Massari, Marc R. Matrana, Holger Moch and Marina Scarpelli.


View Abstract


Ubiquitin and ubiquitin-like proteins in cardiac disease and protection


Jie Li, John A. Johnson and Huabo Su.


View Abstract


Chemical Structure Similarity Search for Ligand-Based Virtual Screening: Methods and Computational Resources


Xin Yan, Chenzhong Liao, Zhihong Liu, Arnold T. Hagler, Qiong Gu and Jun Xu.


View Abstract


Multi-Target Mining of Alzheimer Disease Proteome with Hansch’s QSBR-Perturbation Theory and Experimental-Theoretic Study of New Thiophene Isosters of Rasagiline


Paula Abeijón, Xerardo García-Mera, Olga Caamaño, Matilde Yañez, Edgar López-Castro, Francisco J. Romero-Durán and Humberto González-Díaz.


View Abstract


Trends in nanomaterials and processing for drug delivery of polyphenols for cancer and other treatments


Joaquim Ciurana and Ciro A Rodríguez.


View Abstract


Sirtuins: a possible clinical implication in cardio- and cerebro- vascular systems.


Valeria Conti, Maurizio Forte, Graziamaria Corbi, Giusy Russomanno, Luigi Formisano, Alessandro Landolfi, V Izzo, Amelia Filippell, Carmine Vecchione and Albino Carrizzo.


View Abstract


Cell Death and microRNAs in Cholestatic Liver Diseases: Update on Potential Therapeutic Applications


Rui Eduardo Castro and Cecília Maria Pereira Rodrigues.


View Abstract


Targeting Transient Receptor Potential Channels in Cardiometabolic Diseases and Myocardial Ischemia Reperfusion Injury


Jipeng Maa, Lifang Yang, Yanyan Maa, Xiaowu Wang, Jun Ren and Jian Yang.


View Abstract


TOPICAL AND TRANSDERMAL DELIVERY OF DRUG-LOADED NANO/MICROSYSTEMS WITH APPLICATION OF PHYSICAL ENHANCEMENT TECHNIQUES


Lívia Neves Borgheti-Cardoso, Tamara Ângelo, Guilherme M. Gelfuso, Renata F.V. Lopez and Taís Gratieri.


View Abstract


Metallothionein as a Scavenger of Free Radicals – New Cardioprotective Therapeutic Agent or Initiator of Tumor Chemoresistance?


Zbynek Heger, Miguel Angel Merlos Rodrigo, Sona Krizkova, Branislav Ruttkay-Nedecky, Marta Zalewska, Elena Maria Planells del Pozo, Aurelie Pelfrene, Bertrand Pourrut, Marie Stiborova, Tomas Eckschlager, Gabriella Emri, Rene Kizek and Vojtech Adam.


View Abstract


From « An enzyme able to destroy penicillin » to carbapenemases: 70 years of beta-lactamase misbehavior


Jean-Marie Frère, Eric Sauvage and Frédéric Kerff.


View Abstract


New pharmacological approaches to the prevention of myocardial ischemia-reperfusion injury


Kai Yee Chin, Chengxue Qin, Lauren May, Rebecca H Ritchie and Owen L Woodman.


View Abstract


Effect of Genetic Polymorphisms (SNPs) in CHRNA7 Gene on Response to Acetylcholinesterase Inhibitors (AChEI) in Patients with Alzheimer’s Disease


Patrizia Russo, Aliaksei Kisialiou, Rossana Moroni, Giulia Prinzi and Massimo Fini.


View Abstract


The chemopreventive activity of β-ionone involves modulation of Rxrα, Rarβ and Coup-Tf1 expression in liver pre-neoplastic lesions in rats


Mônica Testoni Cardozo, Kelly Silva Furtado, Aline De Conti, Fábia de Oliveira Andrade, Laura Helena Gasparini Fernandes, Adriana Campos, Clarissa Scolastici and Fernando Salvador Moreno.


View Abstract


Nanosponge Carriers- An Archetype Swing in Cancer Therapy: A Comprehensive Review


Riyaz Ali M. Osmani, Umme Hani, Rohit R. Bhosale, Parthasarathi K. Kulkarni and S Shanmuganathan.


View Abstract


Possible Effects of Dietary Anthocyanins on Diabetes and Insulin Resistance


Eleonora Turrini, Lorenzo Ferruzzi and Carmela Fimognari.


View Abstract


Decoding the structural basis for carbapenem hydrolysis by class A - lactamases: fishing for a pharmacophore


Donatella Tondi, Simon Cross, Alberto Venturelli, Maria Paola Costi, Gabriele Cruciani and Francesca Spyrakis.


View Abstract


Targeting Receptor Tyrosine Kinases using Monoclonal Antibodies: The Most Specific Tools for Targeted-Based Cancer Therapy


Mahdi Shabani and Mohammad Hojjat-Farsangi.


View Abstract


RECENT INSIGHTS INTO NOTCH SIGNALING IN EMBRYONAL RHABDOMYOSARCOMA


Beatrice Conti, Katherine K. Slemmons, Rossella Rota and Corinne M Linardic.


View Abstract


CADD modeling of multi-target drugs against Alzheimer's disease


Pravin Ambure and Kunal Roy.


View Abstract


Vitamin C and Bone Health: Evidence from Cell, Animal and Human Studies


Kok-Yong Chin and Soelaiman Ima-Nirwana.


View Abstract


PLK1 INHIBITION: PROSPECTIVE ROLE FOR THE TREATMENT OF PEDIATRIC TUMORS


Julia Alejandra Pezuk, Elvis Terci Valera and María Sol Brassesco.


View Abstract


Structure-Function Relationships of Class D Carbapenemases


Jean-Denis Docquier and Stefano Mangani.


View Abstract


Human Immunodeficiency Virus-1 Cell-To-Cell Transmission And Antiviral Strategies: An Overview.


Nicoletta Casartelli.


View Abstract


Molecular Mechanisms of Cholangiocarcinogenesis: New Potential Targets For Therapy


Oihane Erice, Maite Merino-Azpitarte, Ander Arbelaiz, María Gutierrez-Larranaga, Raúl Jiménez-Agüero, María J. Perugorria, Luis Bujanda and Jesús M Banales.


View Abstract


DOCKING STUDIES FOR MULTI-TARGET DRUGS


L. Scotti, F.J.B. Mendonça Júnior, H. Ishiki, F.F. Ribeiro, Singla Rajeev K, J.M. Barbosa Filho, M.S. Da Silva and MT Scotti.


View Abstract


Innate and Adaptive Immune Responses in Chronic HCV infection


Lynn B Dustin.


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How Current Direct-Acting Antiviral and Novel Cell Culture Systems for HCV are Shaping Therapy and Molecular Diagnosis of Chronic HCV Infection


Fabrizio Maggi, Daniele Focosi and Mauro Pistello.


View Abstract


Is Intake of Flavonoid-based Food Supplements during Pregnancy Safe for the Developing Child? A Literature Review.


Marta Barenys, Stefan Masjosthusmann and Ellen Fritsche.


View Abstract


Targeting interferon regulatory factor for cardiometabolic diseases: opportunities and challenges


Zhang Yaxing, Zhang Xiao-Jing and Li Hongliang.


View Abstract


Nano-based Anti-tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis


Rohit Sharma, Amanpreet Kaur, A.K. Sharma, Neeraj Dilbaghi and Anil K Sharma.


View Abstract


Chemokines in the pathogenesis and as therapeutical markers and targets of HCV chronic infection, and HCV extrahepatic manifestations


Poupak Fallahi, Silvia Martina Ferrari, Dilia Giuggioli, Marco Sebastiani, Michele Colaci, Clodoveo Ferri and Alessandro Antonelli.


View Abstract


Phospholipase A2 Isoforms as Novel Targets for Prevention and Treatment of Inflammatory and Oncologic Diseases


Nagendra Sastry Yarla, Anupam Bishayee, Lakshmipathi Vadlakonda, Ramakrishna Chintala, Govinda Rao Duddukuri, Pallu Reddanna and DSVGK Kaladhar.


View Abstract


HDL as a Target for Glycemic Control


Boris Waldman, Alicia J. Jenkins, David Sullivan, Martin K.C. Ng and Anthony C Keech.


View Abstract


ALDH2---the Genetic Polymorphism and Enzymatic Activity Regulation: Their Epidemiologic and Clinical Implications


Rui Zhang, Jiali Wang, Mengyang Xue, Feng Xu and Yuguo Chen.


View Abstract


VIRTUAL SCREENING FOR THE DEVELOPMENT OF DUAL-INHIBITORS TARGETING TOPOISOMERASE IB AND TYROSYL-DNA PHOSPHODIESTERASE 1


Francesca Cardamone, Simone Pizzi, Federico Iacovelli, Mattia Falconi and Alessandro Desideri.


View Abstract


Can Targeting the Incretin Pathway Dampen RAGE-Mediated Events In Diabetic Nephropathy?


Karly C. Sourris, Henry Yao, George Jerums, Mark E. Cooper, Elif I. Ekinci and Melinda T Coughlan.


View Abstract


Wnt Signaling in Rhabdomyosarcoma – a Potential Targeted Therapy Option


Eleanor Chen.


View Abstract


SIRT1 as a promising novel therapeutic target for myocardial ischemia reperfusion injury and cardiometabolic disease


Dong Han, Jinda Wang, Sai Ma, Yundai Chen and Feng Cao.


View Abstract


Chronic exposure to low-level cadmium in diabetes: role of oxidative stress and comparison with polychlorinated biphenyls.


Adeline Jacquet, Faycal Ounnas, Marine Lenon, Josiane Arnaud, Christine Demeilliers and Jean-Marc Moulis.


View Abstract


Antioxidants as a Potential Preventive and Therapeutic Strategy for Cadmium


Malgorzata M. Brzóska, Sylwia Borowska and Michal Tomczyk.


View Abstract


Redox-Related Mechanisms to Rebalance Cancer-Deregulated Cell Growth The Anticarcinogenic Mechanisms of Regeneration


An-Sofie Stevens, Nicky Pirotte, Annelies Wouters, Andromeda Van Roten, Frank Van Belleghem, Maxime Willems, Ann Cuypers, Tom Artois and Karen Smeets.


View Abstract


Gastric Carcinoma at the Era of Targeted Therapies


Johann DREANIC, Marion DHOOGE, Elena SION, Catherine BREZAULT, Stanislas CHAUSSADE and Romain CORIAT.


View Abstract


Interfering with Hedgehog Pathway: New Avenues for Targeted Therapy in Rhabdomyosarcoma


Gabriele Manzella and Beat W Schäfer.


View Abstract


New advances in the molecular mechanisms driving biliary fibrosis and emerging molecular targets


A Santos-Laso, P Munoz-Garrido, M Felipe-Agirre, L Bujanda, J M Banales and M J Perugorria.


View Abstract


Doxorubicin action on mitochondria: relevance to osteosarcoma therapy?


Jo Armstrong and Crispin R Dass.


View Abstract


Endoplasmic Reticulum Stress, Calcium Dysregulation and Altered Protein Translation: Intersection of Processes that Contribute to Cancer Cachexia Induced Skeletal Muscle Wasting


S. T. Isaac, T. C. Tan and P Polly.


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Cancellers - Exploring the Possibility of Receptor Decoy Traps as a Superior Anti-Retroviral Strategy


Sundararaj Stanley Jeremiah, Kenji Ohba and Naoki Yamamoto.


View Abstract


Pharmacological interference with protein-protein interactions of A-kinase anchoring proteins as a strategy for the treatment of disease


Veronika A. Deak and Enno Klussmann.


View Abstract


Mini Review: Pathophysiology of Erectile Dysfunction


Hotaka Matsui, Nikolai A. Sopko, Johanna L. Hannan and Trinity J Bivalacqua.


View Abstract


Do we need full donor chimerism? How alloreactive cell therapies without substantial engraftment might treat hematologic cancers


Elizabeth F. Krakow, Hui-Sheng Ai, Brian Shaffer, Jean-Sébastien Delisle, Kai-Xun Hu and Anthony D Sung.


View Abstract


Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma


Sergio A Gradilone, María J Lorenzo Pisarellob and Nicholas F LaRussob.


View Abstract


Docetaxel/2-Hydroxypropyl β-Cyclodextrin Inclusion Complex Increases Docetaxel Solubility and Release from a Nanochannel Drug Delivery System


Silvia Ferrati, Eugenia Nicolov, Shyam Bansal, Sharath Hosali, Melissa Landis and Alessandro Grattoni.


View Abstract


Molecular Bases Of Chemoresistance In Cholangiocarcinoma


J JG Marin, E Lozano, O Briz, R Al-Abdulla, M A Serrano and R IR Macias.


View Abstract


MicroRNAs in breast cancer: one More Turn in Regulation


P Eroles, E Tormo, B Pineda, E Espin and A Lluch.


View Abstract


Architectural Clones in Aplastic Anaemia- Lessons Learned from High Throughput Sequencing


Austin G Kulasekararaj and Judith C W Marsh.


View Abstract


Matched Sibling Donor Hematopoietic Stem Cell Transplant in Patients with Acquired Aplastic Anemia


André Tichelli and Jakob R Passweg.


View Abstract


Systemic Delivery of Free Chitosan Accelerates Femur Fracture Healing in Rats


Peng Shao, Yongzhong Wei, Crispin R. Dass, Guoying Zhang and Zhisheng Wu.


View Abstract


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