ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)


Volume 16, 14 Issues, 2015


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Current Drug Targets

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Ranking and Category:
  • 52nd of 254 in Pharmacology & Pharmacy

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Editor-in-Chief:
Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA


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Current: 3.597
5 - Year: 3.558

Upcoming Articles (E-Pub Abstracts ahead of Print)

Macrophages and Dendritic Cells: The Usual Suspects in Atherogenesis
Christina Kassiteridi and Claudia Monaco
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Targeting Angiogenic Pathways in Colorectal Cancer: Complexities, Challenges and Future Directions
Khurum Khan, David Cunningham and Ian Chau
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A Comprehensive Review on miR-200c, a Promising Cancer Biomarker with Therapeutic Potential
Suresh Kumar, Alo Nag and Chandi C. Mandal
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The link between Hepatic Vitamin A Metabolism and Nonalcoholic Fatty Liver Disease
Guoxun Chen
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Is there a Role for Bevacizumab in Non-Glial Tumors?
Elisa Trevisan
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Molecular Pathophysiology of Cavernous Nerve Injury and Identification of Strategies for Nerve Function Recovery after Radical Prostatectomy
Emmanuel Weyne
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Pattern Recognition by CD6: a Scavenger-Like Lymphocyte Receptor
Adelaida Sarukhan, Mario Martinez-Florensa, Cristina Escoda-Ferran, Esther Carrasco, Esther Carreras and Francisco Lozano
View Abstract
Metabotropic Glutamate Receptors in Central Nervous System Diseases
Anna V. Golubeva, Rachel D. Moloney, Richard M. O’Connor, Timothy G. Dinan and John F. Cryan
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Targeting AMPK signaling pathway to overcome drug resistance for cancer therapy
Zhiyu Wang, Pengxi Liu, Qianjun Chen, Shigui Deng, Xiaoyan Liu, Honglin Situ, Shaowen Zhong, Swei Hann and Yi Lin
View Abstract
MicroRNAs and the Response of Prostate Cancer to Anti-Cancer Drugs
Marzia Pennati, Marco Folini, Paolo Gandellini and Nadia Zaffaroni
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Nano Traditional Chinese Medicine: Current Progresses and Future Challenges
Songqing Liu, Y i Huang, Fang Liu and Yinglan Zhao
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Dormant Circulating Tumor Cells In Prostate Cancer: Biological, Clinical And Therapeutic Implications
M. J. Alvarez-Cubero, F Vázquez-Alonso, I Puche-Sanz, F. G. Ortega, M. Martin-Prieto, J L Garcia-Puche, M. Pascual-Geler, J A. Lorente, J. M. Cozar-Olmo and M. J. Serrano-Fernández
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Selective modulators of α5-containing GABAA receptors and their therapeutic significance
Ming Shiuan Soh and Joseph W. Lynch
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Heterocyclic Scaffolds: Centrality in Anticancer Drug Development
Imran Ali, Mohammad Nadeem Lone, Zeid A. Al-Othman and Abdulrahman Al-Warthan
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Endogenous Cardioprotective Agents: Role in Pre and Postconditioning
C Penna, R Granata, C G Tocchetti, M P Gallo, G Alloatti and P Pagliaro
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Mini Review: Pathophysiology of Erectile Dysfunction
Hotaka Matsui, Nikolai A. Sopko, Johanna L. Hannan and Trinity J. Bivalacqua
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Metformin for Prevention and Treatment of Colon Cancer: a Reappraisal of Experimental and Clinical Data
Vladimir N. Anisimov
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Immunomodulatory Drugs: IMiDs in Acute Myeloid Leukemia (AML)
Joshua F. Zeidner and Matthew C. Foster
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Hemoglobin degradation pathway of Plasmodium falciparum as antimalarial drug target
Tabish Qidwai
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Do we need full donor chimerism? How alloreactive cell therapies without substantial engraftment might treat hematologic cancers
Elizabeth F. Krakow, Hui-Sheng Ai, Brian Shaffer, Jean-Sébastien Delisle, Kai-Xun Hu and Anthony D. Sung
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Nitroso-Redox Balance and Modulation of Basal Myocardial Function: an Update from the Italian Society of Cardiovascular Research (SIRC)
Carlo G Tocchetti, Marilisa Molinaro, Tommaso Angelone, Vincenzo Lionetti, Rosalinda Madonna, Fabio Mangiacapra, Francesco Moccia, Claudia Penna, Laura Sartiani, Federico Quaini and Pasquale Pagliaro
View Abstract
The Impact of Combination Therapy with a-Blockers and 5ARIs on the Progression of BPH
Petros Sountoulides
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Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma
Sergio A Gradilone, María J Lorenzo Pisarellob and Nicholas F LaRussob
View Abstract
How to Manage Infections Caused by Antibiotic Resistant Gram-negative Bacteria - EBMT Educational Meeting from the Severe Aplastic Anaemia and Infectious Diseases Working Parties, Naples, Italy, 2014
Małgorzata Mikulska
View Abstract
Docetaxel/2-Hydroxypropyl β-Cyclodextrin Inclusion Complex Increases Docetaxel Solubility and Release from a Nanochannel Drug Delivery System
Silvia Ferrati, Eugenia Nicolov, Shyam Bansal, Sharath Hosali, Melissa Landis and Alessandro Grattoni
View Abstract
Molecular Bases Of Chemoresistance In Cholangiocarcinoma
J JG Marin, E Lozano, O Briz, R Al-Abdulla, M A Serrano and R IR Macias
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Discovery of Novel Anti-Diabetic Drugs by Targeting Lipid Metabolism
Xiu Zhou, Jun Xu, Yuguang Shi and Ye Ji-Ming
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Novel Antigen Targets for Immunotherapy of Acute Myeloid Leukemia
Meghali Goswami and Christopher S. Hourigan
View Abstract
The Epidemiological, Mechanistic and Potential Clinical Role of AR in Urothelial Carcinoma
Maria T Bourlon, Thomas W Flaig, Division of Medical Oncology University of Colorado Cancer Center MS 8117, 12801 E. 17th Avenue, Room 8117 , Aurora and CO 80045 Thomas.Flaig@ucdenver.edu
View Abstract
Stem Cell Transplant from Unrelated Donor in Patients with Severe Aplastic Anemia: Indications, Donor Selection, Conditioning, GVHD Prophylaxis
Anna Paola Iori, Emilia Scalzulli, Laura Lombardi, Giovanni Fernando Torelli and Walter Barberi
View Abstract
MicroRNAs in breast cancer: one More Turn in Regulation
P Eroles, E Tormo, B Pineda, E Espin and A Lluch
View Abstract
Steps and Routes of HCV Infection: the Great Promise of new Anti-Viral Targets
Annalisa Crema, Antonio Ponzetto, Massimo Clementi and Guido Carloni
View Abstract
Predictive Diagnostic Pathology in the Target Therapy Era in Breast Cancer
Caterina Marchiò, Davide Balmativola, Roberta Castiglione, Laura Annaratone and Anna Sapino
View Abstract
Multiscale Imaging of Nanoparticle Drug Delivery
Lawrence W. Dobrucki, Dipanjan Pan and Andrew M. Smith
View Abstract
Antimicrobial and Antioxidant Properties of Satureja Montana L. and S. Subspicata Vis. (Lamiaceae)
Dario Kremer, Iztok Jože Košir, Marijana Zovko Končić, Andreja Čerenak, Tanja Potočnik, Siniša Srečec, Marko Randić and Ivan Kosalec
View Abstract
Roles of Apoptosis and Cellular Senescence in Cancer and Aging
Claudia Cerella, Cindy Grandjenette, Mario Dicato and Marc Diederich
View Abstract
"Penile Rehabilitation After Radical Prostatectomy"
David Jacques Cohen and Sidney Glina
View Abstract
The Role of JNK Signalling in Responses to Oxidative DNA Damage
Zeeshan Shaukat, Dawei Liu, Rashid Hussain, Mahwish Khan and Stephen L. Gregory
View Abstract
Cardioprotection by Targeting the Pool of Resident and Extracardiac Progenitors
Konrad Urbanek, Caterina Frati, Gallia Graiani, Denise Madeddu, Angela Falco, Stefano Cavalli, Bruno Lorusso, Andrea Gervasi, Lucia Prezioso, Monia Savi, Francesca Ferraro, Federica Galaverna, Pietro Rossetti, Costanza Annamaria Lagrasta, R e Fancesca, Eugenio Quaini, Francesco Rossi, Antonella De Angelis and Federico Quaini
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(1→3)-α-D-Glucans from Aspergillus spp.: Structural Characterization and Biological Study on Their Carboxymethylated Derivatives
Adrian Wiater, Roman Paduch, Adam Choma, Stączek Sylwia, Małgorzata Pleszczyńska, Michał Tomczyk, Marcello Locatelli and Szczodrak Janusz
View Abstract
The Impact of the Emerging Genomics Data on the Management of Age-Related Phenotypes in the Context of Cellular Senescence
Alberto Montesanto, Silvana Geracitano, Sabrina Garasto, Sergio Fusco, Fabrizia Lattanzio, Giuseppe Passarino and Andrea Corsonello
View Abstract
Architectural Clones in Aplastic Anaemia- Lessons Learned from High Throughput Sequencing
Austin G Kulasekararaj and Judith C W Marsh
View Abstract
Phosphonate Emerging Zinc Binding Group in Matrix Metalloproteinase Inhibitors
Cristina Campestre, Mariangela Agamennone, Marilena Tauro and Paolo Tortorella
View Abstract
Hyaluronic Acid as a Protein Polymeric Carrier: an Overview and a Report on Human Growth Hormone
Anna Mero, Monica Campisi, Michele Caputo, Christian Cuppari, Antonio Rosato, Oddone Schiavon and Gianfranco Pasut
View Abstract
Protective Effect of Aronia Melanocarpa Polyphenols on Cadmium Accumulation in the Body: a Study in a Rat Model of Human Exposure to this Metal
Malgorzata M. Brzóska, Malgorzata Galażyn-Sidorczuk, Maria Jurczuk and Michal Tomczyk
View Abstract
OPA1 in Cardiovascular Health and Disease
N Burke, A R Hall and D J Hausenloy
View Abstract
Recent Advances in Optical Molecular Imaging and its Applications in Targeted Drug Delivery
Xibo Ma, Hui Hui, Wenting Shang, Xiaohua Jia and Jie Tian
View Abstract
Matched Sibling Donor Hematopoietic Stem Cell Transplant in Patients with Acquired Aplastic Anemia
André Tichelli and Jakob R. Passweg
View Abstract
Indoxyl Sulfate: a Candidate Target for the Prevention and Treatment of Cardiovascular Disease in Chronic Kidney Disease
Chiara Barisione, Giorgio Ghigliotti, Marco Canepa, Manrico Balbi, Claudio Brunelli and Pietro Ameri
View Abstract
Molecular Imaging of Therapeutic Potential of Reporter Probes
Bhushan Thakur, Subhoshree Chatterjee, Smrita Chaudhury and Pritha Ray
View Abstract
Intracellular Ca2+ Signals to Reconstruct a Broken Heart: Still a Theoretical Approach?
Francesco Moccia, Federico Alessandro Ruffinatti and Estella Zuccolo
View Abstract
Aquaporin-1 and Sodium-Hydrogen Exchangers as Pharmacological Targets in Diabetic Atherosclerosis
Rosalinda Madonna and Raffaele De Caterina
View Abstract
Micrornas As Tools And Effectors For Patient Treatment In Gastrointestinal Carcinogenesis
Edoardo D`Angelo, Caterina Vicentini, Marco Agostini, Andras Kiss, Raffaele Baffa, Aldo Scarpa and Matteo Fassan
View Abstract
Image Guidance in Stem Cell Therapeutics: Unfolding the Blindfold
Amirali B. Bukhari, Shruti Dutta and Abhijit De
View Abstract
Aqueous Extracts of Selected Potentilla Species Modulate Biological Activity of Human Normal Colon Cells
Roman Paduch, Adrian Wiater, Marcello Locatelli, Małgorzata Pleszczyńska and Michał Tomczyk
View Abstract
Stem cell aging and age-related cardiovascular disease: Perspectives of treatment by ex-vivo stem cell rejuvenation
Madonna Rosalinda, Engel B. Felix, M Davidson Sean, Ferdinandy Péter, Görbe Anikó, P.G. Sluijter Joost and W Van Laake Linda
View Abstract
Immobilization and Detection Strategies for Multifunctional Glycochips
Gangliang Huang, Qilin Tang and Xin Chen
View Abstract
The Activated Endocannabinoid System in Atherosclerosis: Driving Force or Protective Mechanism?
Sabine Steffens and Pál Pacher
View Abstract
Personalized Drug Therapy in Cystic Fibrosis: From Fiction to Reality
Fernando Augusto de Lima Marson, Carmen Silvia Bertuzzo and Jose Dirceu Ribeiro
View Abstract
Auto-antibodies as possible markers and mediators of ischemic, dilated, and rhythmic cardiopathies.
Nathalie Satta and Nicolas Vuilleumier
View Abstract
Biomedical Imaging in Implantable Drug Delivery Systems
Haoyan Zhou, Christopher Hernandez, Monika Goss, Anna Gawlik and Agata A. Exner
View Abstract
Bioactive Food Components as Dietary Intervention for Cystic Fibrosis
Nualpun Sirinupong and Zhe Yang
View Abstract
Polymeric Aggregates in Ionic Liquids: the Green Future of the Delivery Systems
Guido Angelini and Carla Gasbarri
View Abstract
Molecular Pathophysiology of Priapism: Emerging Targets
Uzoma A. Anele, Belinda F. Morrison and Arthur L. Burnett
View Abstract
The role of adipocytokines in atherogenesis and atheroprogression
Federico Carbone, François Mach and Fabrizio Montecucco
View Abstract
Proteomic profiling of a biomimetic drug delivery platform
Claudia Corbo, Alessandro Parodi, Michael Evangelopoulos, David A. Engler, Risë K. Matsunami, Anthony C. Engler, Roberto Molinaro, Shilpa Scaria, Francesco Salvatore and Ennio Tasciotti
View Abstract
CYLD-Mediated Signaling and Diseases
Bryan J. Mathis, Yimu Lai, Chen Qu, Joseph S. Janicki and Taixing Cui
View Abstract
Preparation of Multifunctional Nanoprobes for Tumor-Targeted Fluorescent Imaging and Therapy
Mi Zhou, Xiao Xiao, Adnan A. Kadi, Hoong-kun Fun, Jinbo Li and Yan Zhang
View Abstract
Multistage Nanovectors Enhance the Delivery of Free and Encapsulated Drugs
Jonathan O. Martinez, Michael Evangelopoulos, Rohan Bhavane, Stefania Acciardo, Francesco Salvatore, Xuewu Liu, Mauro Ferrari and Ennio Tasciotti
View Abstract
Systemic Delivery of Free Chitosan Accelerates Femur Fracture Healing in Rats
Peng Shao, Yongzhong Wei, Crispin R. Dass, Guoying Zhang and Zhisheng Wu
View Abstract
Image-Guided Drug Delivery with Single-Photon Emission Computed Tomography: A Review of Literature
Rubel Chakravarty, Hao Hong and Weibo Cai
View Abstract
Silencing of Tumor Necrosis Factor Receptor-1 in Human Lung Microvascular Endothelial Cells using Particle Platforms for siRNA Delivery
Litao Bai, Helen A. Andersson, Kellie McConnell, Diana Chan, Michael Hernandez, Javier Gonzalez, Xuewu Liu, Saverio La Francesca, Jason Sakamoto and Rita E. Serda
View Abstract
Penetration Enhancer-Containing Vesicles: Does the Penetration Enhancer Structure Affect Topical Drug Delivery?
Anna Maria Fadda
View Abstract
Supramolecular Nanomedicine - An Overview
Bhupinder Singh Sekhon
View Abstract
αIIbβ3-Integrin Ligands: Abciximab and Eptifibatide as Proapoptotic Factors in MCF-7 Human Breast Cancer Cells
Joanna Kononczuk, Arkadiusz Surazynski, Urszula Czyzewska, Izabela Prokop, Michal Tomczyk, Jerzy Palka and Wojciech Miltyk
View Abstract
Safety of Nanoparticles in Medicine
Joy Wolfram, Motao Zhu, Yong Yang, Jianliang Shen, Emanuela Gentile, Donatella Paolino, Massimo Fresta, Guangjun Nie, Chunying Chen, Haifa Shen, Mauro Ferrari and Yuliang Zhao
View Abstract
Non-small Cell Lung Carcinoma: An Overview on Targeted Therapy
Ana Vanessa Nascimento, Hassan Bousbaa, Domingos Ferreira and Bruno Sarmento
View Abstract
Genomic identification of potential targets unique to Candida albicans for the discovery of antifungal agent
Himanshu Tripathi, Suaib Luqman, Abha Meena and Feroz Khan
View Abstract
A Review on Skin Targeted Delivery of Bioactives as 2 Ultradeformable Vesicles: Overcoming the Penetration Problem
Priyanka Karunanidhi and Singh Sanjay
View Abstract
Editorial:Mirnas as Legitimate Targets for Cancer Therapy
Wang Z
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