Home Page ::: Letters in Drug Design & Discovery

ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 11, 10 Issues, 2014


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Letters in Drug Design & Discovery

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Editor-in-Chief:

Atta-ur-Rahman

, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

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"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Authors' Comments
The review process of my article, accepted in the journal “Letters in Drug Design & Discovery”, went smoothly with prompt action. In my opinion, the journal LDDD should emerge as a leading journal in the area of drug design and discovery, as to my knowledge there are only a few journals that focus solely on this area. Nevertheless, I am a regular contributor to this journal and would like to continue to submit my future research work to LDDD.

Dr. Manojit Pal
Has contributed: Synthesis and Cyclooxygenase-2 (COX-2) Inhibiting Properties of 1,5- Diarylpyrazoles Possessing N-Substitution on the Sulfonamide (-SO2NH2) Moiety†

Letters in Drug Design & Discovery

,

Volume 11

-

Number 8



Synthesis and Antimycobacterial Activity of Highly Functionalised Pyrrolothiazole Derivatives

; Pp: 968 - 974

Abdulrahman I. Almansour, Venu Sanjeevi Lakshmipathi, Elumalai Manogaran, Mohamed Ashraf Ali, Farzana Beevi, Tan Soo Choon, Ang Chee Wei, Raju Suresh Kumar and Mohammad Asad


DOI: 10.2174/1570180811666140506204239


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Synthesis and Biological Activity of Novel 1-((benzofuran-2-yl)methyl)-1Htriazole Derivatives

; Pp: 975 - 984

Yi-Min Shi, Li-Juan Yang, Wen Chen, Cheng-Jun Sun, Xiao-Liang Xu, Shu-Ya Zhou, Hong- Bin Zhang and Xiao-Dong Yang


DOI: 10.2174/1570180811666140423214501


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Library of Synthetic Compounds Based on Pyrazole Unit: Design and Screening Against Breast and Colorectal Cancer

; Pp: 1010 - 1016

Farid Abrigach, Mohamed Khoutoul, Noureddine Benchat, Smaail Radi, Nihed Draoui, Olivier Feron, Olivier Riant and Rachid Touzani


DOI: 10.2174/1570180811666140512220842


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Design, Synthesis and Biological Evaluation of Benzimidazole-Pyridine-Piperidine Hybrids as a new class of potent Antimicrobial Agents


Kothapally Beulah, Akula Ravi Kumar, Boddupally Peda Venkat Lingaiah, Pamulaparthy Shanthan Rao, Banda Narsaiah, Aaramadaka Sunil Kumar Reddy and Upadhyayula Surya Narayana Murty


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Synthesis and Analgesic Activity of 3, 7-Dimethylpurine-2, 6-Dion-1-yl Derivatives of Acetic and Butanoic Acid


Malgorzata Zygmunt, Pawel Zmudzki, Grazyna Chlon-Rzepa, Jacek Sapaa and Maciej Pawlowski


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Pd/C-Mediated Synthesis of 3-Methyleneisoindolin-1-ones: Biological and Theoretical Study of their PDE4 Inhibition


Suryadevara Vijayavardhini, Dandela Rambabu, Vegendla Radha, Ravikumar Kapavarapu, Mandava Venkata Basaveswara Rao and Manojit Pal


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Synthesis and Evaluation of Bis-pyrazolineDerivatives as Potential Antimicrobial Agents


Mehlika Dilek Altıntop, Usama Abu Mohsen, Hulya Karaca, Zerrin Cantürk and Ahmet Ozdemir


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Design, Synthesis and in vitro Cytotoxicity Evaluation of new 3', 4'-bis (3, 4, 5-Trisubstituted)-4'H-Spiro [Indene-2, 5'-Isoxazol]-1(3H)-one Derivatives as Promising Anticancer Agents


Hoda Abolhasani, Afshin Zarghi, Ahmad Abolhasani, Maryam Hamzeh-Mivehroud, Nasrin Bargahi, Behrouz Notash, Javid Shahbazi Mojarrad and Siavoush Dastmalchi


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Pd/C-Catalyzed Synthesis of (E)-2-Arylmethylideneindolin-3-ols under Ultrasound: Their Initial Evaluation as Potential Anti-Proliferative Agents


Ponugubati Radhakrishna Murthi, Namburi Suresh, Chekuri Sharmila, Rani, Mandava Venkata Basaveswara Rao and Manojit Pal


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Alzheimer's Disease Prevention and use of Traditional Plant Medicines


Xiaogang Wang, Raphael Dubois and James David Adams


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Theoretical Modelling of Potential Chk1 Inhibitors


Pedro M.M. Araújo, Luís Pinto da Silva and Joaquim C.G. Esteves da Silva


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Identification of Novel GSK1070916 Analogs as Potential Aurora B Inhibitors: Insights from Molecular Dynamics and MM/GBSA based Rescoring


Faraz Shaikh, Soumendranath Bhakat, Abhishek Thakur, Ashish Radadia, Mahmoud E. S. Soliman and Anamik Shah


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An Improved Synthesis of (Z)-2-(5-Amino-1, 2, 4-thiadiazol-3-yl)-2- (Ethoxyimino) Acetic Acid


Songqing Wang, Yi Yao, Kai Chen, Zhujun Fang, Lexian Tong and Weihui Zhong


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In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4

, 2014 :11(7); 825 - 832

Wolfgang Walther, Iduna Fichtner, Frauke Hackenberg, Wojciech Streciwilk and Matthias Tacke


DOI: 10.2174/1570180811666140529004102
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Analysis of Proteasome Inhibition Prediction Using Atom-Based Quadratic Indices Enhanced by Machine Learning Classification Techniques

, 2014 :11(6); 705 - 711

Gerardo M. Casanola-Martin, Huong Le-Thi-Thu, Yovani Marrero-Ponce, Juan A Castillo- Garit, Francisco Torrens, Facundo Perez-Gimenez and Concepcion Abad


DOI: 10.2174/1570180811666140122001144
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Potent Neuroprotective Activity of Monoterpene Derived 4-[(3aR,7aS)- 1,3,3a,4,5,7a-Hexahydro-3,3,6-trimethylisobenzofuran-1-yl]-2-methoxyphenol in MPTP Mice Model

, 2014 :11(5); 611 - 617

Alla V. Pavlova, Irina V. Il'ina, Ekaterina A. Morozova, Dina V. Korchagina, Svetlana Yu. Kurbakova, Irina V. Sorokina, Tatyana G. Tolstikova, Konstantin P. Volcho and Nariman F. Salakhutdinov


DOI: 10.2174/1570180811666131210000316
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Synthesis and Anti-Proliferative Activity of New Biphenyle-Benzylidenethiazolidine- 2,4-dione Bis-Adducts Containing Various Heterocyclic Cores

, 2014 :11(3); 256 - 264

Maxime Meyer, Sandra Kuntz, Isabelle Grillier-Vuissoz, Helene Martin, Lysiane Richert, Stephane Flament, Yves Chapleur and Michel Boisbrun


DOI: 10.2174/15701808113106660080
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Biochemical Changes Evidenced in Alzheimer's Disease: A Mini-Review

, 2014 :11(2); 240 - 248

Luciana Scotti, Francisco Jaime Bezerra Mendonça Junior, Marcelo Sobral da Silva, Ivan R. Pitta and Marcus Tullius Scotti


DOI: 10.2174/15701808113109990063
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