E-Pub Articles Ahead of Print ::: Medicinal Chemistry

ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)


Volume 12, 8 Issues, 2016


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Medicinal Chemistry

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Kings College
University of Cambridge
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E-Pub Articles Ahead of Print

Elucidation of Antiangiogenic Potential of Vitexin Obtained from Cucumis Sativus Targeting Hsp90 Protein: A Novel Multipathway Targeted Approach to Restrain Angiogenic Phenomena


Neha Sharma, Salman Akhtar, Qazi M. Sajid Jamal, Mohammad A. Kamal, M. Kalim A. Khan, M. Haris Siddiqui and Usman Sayeed.


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A Microwave-Promoted/Assisted Method for Rapid Prepararation of Biaryl Seven-membered Lactones


Chunqi Hu, Jun Li and Wenting Du.


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Molecular Docking and Pharmacophore Modeling Studies of Fluorinated Benzamides as Potential CETP Inhibitors


Reema Abu Khalaf, Sarah Al-Rawashdeh, Dima Sabbah and Ghassan Abu Sheikha.


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Synthesis and Biological Evaluation of Benzophenone Derivatives as Potential HIV-1 Inhibitors


Zhendong Song, Ping Wang, Shanshan Huang, Changyuan Wang, Ruirui Wang, Liumeng Yang, Yuhong Zhen, Kexin Liu, Yongtang Zheng and Xiaodong Ma.


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Synthesis, Antitubercular and Anticancer Activities of p-nitrophenylethylenediamine- Derived Schiff Bases


Raquel S. Amim, Cláudia Pessoa, Maria C. S. Lourenço, Marcus V. N. de Souza and Josane A Lessa.


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Anti-inflammatory and Hypolipidemic Effect of Novel Conjugates with Trolox and Other Antioxidant Acids


Panagiotis Theodosis-Nobelos, Panos N. Kourounakis and Eleni A Rekka.


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Antioxidant and Anticholinesterase Activities of Some Dialkylamino Substituted 3-hydroxyflavone Derivatives


Burcu Culhaoglu, Asli Capan, Mehmet Boga, Mehmet Ozturk, Turan Ozturk and Gulacti Topcu.


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Cytotoxic Phyllactone Analogs from the Marine Sponge Phyllospongia papyrecea


Huawei Zhang, Phillip Crews, Karen Tenney and Frederick A Valeriote.


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Gastrointestinal Motility and Acute Toxicity of Pistagremic acid Isolated from the Galls of Pistacia integerrima


Abdur Rauf, Tareq Abu-Izneid, Aneela Maalik, Saud Bawazeer, Ajmal Khan, Taibi Ben Hadda, Haroon Khan, Mohamed Fawzy Ramadan, Imran Khan, Mohammad S. Mubarak, Ghias Uddin, Alia Bahadar and Umar Farooq.


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Anti-inflammatory, analgesic and anti-ulcerogenic activities of novel bis-thiadiazoles, bis-thiazoles and bis-formazanes


Zeinab A. Muhammad, Ghada S. Masaret, Mohamed M. Amin, Magda A. Abdallah and Thoraya A Farghaly.


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Discovery of Flexible Naphthyltriazolylmethane-based Thioacetic Acids as Highly Active Uric Acid Transporter 1 (URAT1) Inhibitors for the Treatment of Hyperuricemia of Gout


Xiansheng Zhang, Jingwei Wu, Wei Liu, Yuqiang Liu, Yafei Xie, Qian Shang, Zhixing Zhou, Weiren Xu, Lida Tang, Jianwu Wang and Guilong Zhao.


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Thio- and semicarbazones: Hope in the search for treatment of Leishmaniasis and Chagas disease


Barbara V. da Silva and Bianca N M Silva.


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Docking Studies, Synthesis and Biological Evaluation of β-aryl-β-hydroxy propanoic Acids for Anti-inflammatory Activity


Jelena Savić, Sanda Dilber, Marina Milenković, Jelena Kotur-Stevuljević, Bojan Marković, Sote Vladimirov and Jasmina Brborić.


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Microwave-assisted Synthesis of 2-Styrylquinoline-4-carboxylic Acids as Antitubercular Agents


Gisela C. Muscia, Silvia E. Asis and Graciela Y Buldain.


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Effect of O6-Substituted Guanine Analogs on O6-Methylguanine DNA-Methyltransferase Expression and Glioblastoma Cells Viability


Patrick-Denis St-Coeur, Marc Cormier, Véronique C. LeBlanc, Pier Jr Morin and Mohamed Touaibia.


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Differences in Antiproliferative Activity between Salinomycin-AZT Conjugates Obtained via ‘Click’ and Esterification Reactions


Michał Antoszczak, Ewa Maj, Natalia Kleczewska, Joanna Wietrzyk, Lech Celewicz and Adam Huczyński.


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Synthesis, Screening and in silico Simulations of Anti-Parasitic Propamidine/Benzimidazole Derivatives


Carlos A. Méndez-Cuesta, Miguel Ángel Herrera-Rueda, Sergio Hidalgo-Figueroa, Hugo Tlahuext, Rosa Moo-Puc, Juan Bautista Chale-Dzul, Manuel Chan-Bacab, Benjamín Otto Ortega-Morales, Emanuel Hernández-Núñez, Oscar Méndez-Lucio, José L. Medina-Franco and Gabriel Navarrete-Vazquez.


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Tamoxifen and Fulvestrant Hybrids Showed Potency as Selective Estrogen Receptor Down-Regulators


Takuji Shoda, Masashi Kato, Takuma Fujisato, Yosuke Demizu, Hideshi Inoue, Mikihiko Naito and Masaaki Kurihara.


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Synthesis, Characterization and Biological Activities of Creatinine Amides and Creatinine Schiff Bases


Amara Mumtaz, Sumera Zaib, Fareeha Zahoor, Azhar Nawaz, Aamer Saeed, Amir Waseem, Afsar Khan, Izhar Hussain and Jamshed Iqbal.


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The Role of Size in Development of Mucosal Liposome-Lipopeptide Vaccine Candidates against Group A Streptococcus


Khairunnisa Abdul Ghaffar, Nirmal Marasini, Ashwini Kumar Giddam, Michael R. Batzloff, Michael F. Good, Mariusz Skwarczynski and Istvan Toth.


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Inhibition of Molecular Signaling in Huh-7 Cells by AM3: A Novel Chemotherapeutic Agent for Hepatocellular Carcinoma


Chun-Lung Yuan, Shih-Wei Lin and Meng-Hsuan Cheng.


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Synthesis, Biological Evaluation and Molecular Docking of New Benzenesulfonylhydrazone as Potential Anti-Trypanosoma Cruzi Agents


Silvia Elizondo-Jimenez, Antonio Moreno-Herrera, Rogelio Reyes-Olivares, Edith Dorantes-Gonzalez, Benjamín Nogueda-Torres, Eduardo Alves Gamosa de Oliveira, Nelilma C. Romeiro, Lidia Moreira Lima, Isidro Palos and Gildardo Rivera.


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Synthesis, Antioxidant and Anti-inflammatory Properties of an Apocynin- Derived Dihydrocoumarin


Luana Chiquetto Paracatu, Maria Luiza Zeraik, Luiza de Carvalho Bertozo, Aloisio de Andrade Bartolomeu, Luiz Carlos da Silva Filho, Luiz Marcos da Fonseca and Valdecir Farias Ximenes.


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Antimicrobial activity of new 2-Thioxo-benzo[g]quinazolin-4(3H)-one derivatives


Rashad Al-Salahi, Hatem A. Abuelizz, Rabab El Dib and Mohamed Marzouk.


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Benzoflavonoids Structure Hinders Human Colon Cancer Clonogenicity


Yeonjoong Yong, Eun Jee Koh, Seunghyun Ahn, Beom Soo Kim, Young Lee, Soon Young Shin and Yoongho Lim.


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Cystic Fibrosis Revisited - a Review Study


Blanka Klimova, Kamil Kuca, Michal Novotny and Petra Maresova.


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Non-Imidazole Histamine H3 Ligands. Part VI. Synthesis and Preliminary Pharmacological Investigation of Thiazole-Type Histamine H3-Receptor Antagonists with Lacking a Nitrogen Nucleus in the Side Chain


Roman Guryn, Marek Staszewski, Piotr Kopczacki and Krzysztof Walczyński.


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Synthesis and Biological Activities of Lanthanide (III) Nitrate Complexes with N-(2-hydroxynaphthalen-1-yl) methylene) Nicotinohydrazide Schiff Base


Ahmed K. Hijazi, Ziyad A. Taha, Abdulaziz M. Ajlouni, Waleed M. Al-Momani, Idris M. Idris and Eman Abu Hamra.


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cis-2-Alkenoic acids as promising drugs for the control of biofilm infections


Kamila Tomoko Yuyama and Wolf-Rainer Abraham.


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Synthesis of 1,4-disubstituted 1,2,3-triazole Derivatives Using Click Chemistry and their Src Kinase Activities


Alexandre Lebeau, Cyril Abrioux, David Bénimèlis, Zohra Benfodda and Patrick Meffre.


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Cell-based Assays for Assessing Toxicity: A Basic Guide


Raveen Parboosing, Gugulethu Mzobe, Louis Chonco and Indres Moodley.


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Fluorescein-labeled Bacitracin and Daptomycin Conjugates: Synthesis, Fluorescence Imaging and Evaluation


Sumbla Sheikh, Alexander Sturzu, Hubert Kalbacher, Thomas Nägele, Christopher Weidenmaier, Marius Horger, Christian Schwentner, Ulrike Ernemann and Stefan Heckl.


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Current medical treatment of early breast cancer


Franco Lumachi.


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