E-Pub Articles Ahead of Print ::: Letters in Drug Design & Discovery

ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 11, 10 Issues, 2014


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Letters in Drug Design & Discovery

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

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E-Pub Articles Ahead of Print

Nematicidal Activity of Sprio and Bridged Heterocyclic Neonicotinoid Analogues against Meloidogyne Incognita
Minming Zou, Xue Tian, Nanyang Chen and Xusheng Shao
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Hybrid Pharmacophore Design and Synthesis of Naphthalimide-Benzimidazole Conjugates asPotential Anticancer Agents
Ahmed Kamal, Pogula Praveen Kumar, Mohammed Naseer Ahmed Khan, Bobburi Naga Sheshadri and Olepu Srinivas
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Design, Synthesis and Biological Evaluation of Novel Fluorinated Heterocyclic Hybrid Molecules based on Triazole & Quinoxaline Scaffolds Lead to Highly Potent Antimalarials and Antibacterials
Adimulam Chandra Shekhar, Boddupally Pedda Venkat Lingaiah, Pamulaparthy Shanthan Rao, Banda Narsaiah, Aparna Devi Allanki and Puran Singh Sijwali
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Synthesis and Analysis of Anticonvulsant Activities of new 4-[2-(4-Alkoxybenzylamino)ethyl]-2H-1,2,4-Triazol-3(4H)-one Derivatives
Qing-Kun Shen, Shi-Ben Wang, Hong-Jian Zhang, Guo-Hua Gong and Zhe-Shan Quan
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Promising anticancer drug Candidates based on the 7-Methoxychromone Scaffold: Synthesis and Evaluation of Antiproliferative Activity
Hoang Le Tuan Anh, Nguyen Thi Cuc, Pham Hai Yen, Nguyen Xuan Nhiem, Bui Huu Tai, Do Thi Thao, Nguyen Hoai Nam, Chau Van Minh, Phan Van Kiem and Young Ho Kim
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First Discovery of Tylophora Alkaloids as HIV Inhibitors
Ziwen Wang, Mingxiao Wang, Lei Wang, Xue Yao, Yue Li, Juan Tan, Wentao Qiao, Yunqi Geng, Yuxiu Liu and Qingmin Wang
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Discovery of Novel HDAC Inhibitors by Structure-Based Optimization of Cinnamic Hydroxamic Scaffold
Chengqing Ning, Wenyuan Huang, Wen Wu, Cheng Lu, Yujun He, Lei Yao, Lifei Liu, Xiaohe Zhen, Xiaoyu Liu and Niefang Yu
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Development of Structure Activity Correlation Model on Azetidin-2-ones as Tubulin Polymerization Inhibitors
Vijay K. Patel, Kavibhushan S. Chouhan, Avineesh Singh, Deepak K Jain, Ravichandran Veerasamy, Pradeep K. Singour, Rajesh S. Pawar and Harish Rajak
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Controlled Release from Solid Pharmaceutical Formulations of two N-Alkanoyl-4-Methoxybicyclo [4.2.0] Octa-1, 3, 5-Trien-7-Ethanamines with Melatoninergic Activity
Marilena Vlachou, Vasiliki Ioannidou, Maria Vertzoni, Andrew Tsotinis, Pandelis A. Afroudakis and David Sugden
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Synthesis and Biological Activity of Acylthiourea Derivatives Contain 1,2,3-Thiadiazole and 1,3,4-Thiadiazole
Ming-Yan Yang, Wen Zhao, Zhao-Hui Sun, Cheng-Xia Tan, Jian-Quan Weng and Xing-Hai Liu
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The Novel Derivatives of 3-(Iminomethyl)-2H-Chromen-2-one with Thiourea and Piperazine Structural Motive:Rationale, Synthesis, Antimicrobial and Anti-TB Evaluation
Harshad P. Lakum, Dhruvin R. Shah and Kishor H. Chikhalia
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Docking Study of Novel Pyrrolidine Derivatives as Potential Dipeptidyl Peptidase-Iv (Dpp-Iv) Inhibitors
Sant Kumar Verma, Shashi Kant Sharma and Suresh Thareja
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Role of Curcumin in Modulating Plasma PON1 Arylesterase Activity and Susceptibility to LDL Oxidation in Oxidatively Challenged Wistar Rats
Prabhakar Singh and Syed Ibrahim Rizvi
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Computer-Aided Identification of Novel DprE1 Inhibitors as Potential Anti-TB Lead Compounds: A Hybrid Virtual-Screening and Molecular Dynamics Approach
Yushir Maharaj, Soumendranath Bhakat and Mahmoud E. S. Soliman
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The Synthesis of Risedronic Acid and Alendronate Applying Phosphorus Oxychloride and Phosphorous Acid in Methanesulfonic Acid
Alajos Grun, Rita Kovacs, Sandor Garadnay, Istvan Greiner and Gyorgy Keglevich
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Synthesis, Antimicrobial and Pharmacological Evaluation of Thioureaderivativesof 4H-1, 2, 4-Triazole
Anna Bielenicaa, Ewa Kedzierska, Sylwia Fidecka, Hanna Maluszynska, Barbara Miroslaw, Anna E. Koziol, Joanna Stefanska, Silvia Madeddu, Gabriele Giliberti, Giuseppina Sanna and Marta Struga
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Design, Synthesis and AntitumorActivities of Bis-arylureas and Bisarylamides Based on 1H-benzo[d]imidazole Moiety as Novel BRaf V600E/VEGFR2 Dual Inhibitors
Weimin Yang, Yadong Chen, Yanmin Zhang, Sanzhi Tang, Hongli Chen, Weifang Tang and Tao Lu
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Synthesis and Biological Activity of Thiazole Dithiocarbamate Derivatives
Nalan Gundogdu-Karaburun
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Synthesis and Anticancer Activity of Some 2-[3/4-(2-Substituted Phenyl-2- oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one Derivatives
Nalan Gundogdu-Karaburun, Ahmet Cagri Karaburun, Seref Demirayak, Ismail Kayagil and Leyla Yurttas
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Synthesis and Biological Evaluation of New Tubulin Inhibitors: Shikonin Thio-glycoside Derivatives
Xiao-Ming Wang, Hong-Yan Lin, Jin-Liang Qi, Li-Fei Bai and Yong-Hua Yang
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Fat-Soluble Vitamins Release Based on Clinoptilolite Zeolite as an Oral Drug Delivery System
Mehdi Rahimi, Hamid Mobedi, Aliasghar Behnamghader, Alireza Nateghi Baygi, Houri Mivehchi and Esmaeil Biazar
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Synthesis and Biological Evaluations of 3-Benzothiazol-2-yl Coumarin Derivatives as MEK1 Inhibitors
Chao Wang, Fengrong Xu, Yan Niu, Yun Wu, Jing Sun, Yihong Peng, Lei Liang and Ping Xu
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Synthesis and Biological Evaluation of Arylthiourea Derivatives with Antitubercular Activity
Rusong Luo, Tuomo Laitinen, Liyan Teng, Tapio Nevalainen, Maija Lahtela-Kakkonen, Baofu Zheng, Honghai Wang, Antti Poso and Xuelian Zhang
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Synthesis and Antiproliferative Evaluation of Hybrids of Indolin-2-one and Quinazoline-4(3H)-one Linked via Imine Bond
Wei-Yao Wu, Sheng-Li Cao, Bei-Bei Mao, Ji Liao, Zhong-Feng Li, Hao-Bin Song and Xingzhi Xu
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Construction and High Expression of a Recombinant Amino-Proximal HSV-2 Glycoprotein B Polypeptide with Immunogenicity in Escherichia coli
Xu Ning, Tu Jingjing, Wang Xian Yan and Xu Fang
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Synthesis and Study of Antitumor Activity of Artimisinin Glucoside
Yanrong Ren and Guoping Chen
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Synthesis and Biological Activity of New 2,3-dihydro-1H-cyclopenta[b]- quinoline Derivatives as Acetylcholinesterase Inhibitors
Pawel Szymanski, Magdalena Markowicz, Marek Bajda, Barbara Malawska and Elzbieta Mikiciuk-Olasik
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Novel Aminoalcohol Derivatives Bearing 4-Phenylphenol as Antischistosomal Drugs
Li-Ping Duan, Jian Xue, Yi Tao and Hao-Bing Zhang
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Deformable Surfactant Vesicles Loading Ammonium Glycyrrhizinate: Characterization and In Vitro Permeation Studies
Luisa Di Marzio, Carlotta Marianecci, Federica Rinaldi, Sara Esposito and Maria Carafa
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