E-Pub Articles Ahead of Print ::: Letters in Drug Design & Discovery

ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 11, 10 Issues, 2014


Download PDF Flyer




Letters in Drug Design & Discovery

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 0.961
5 - Year: 0.917

E-Pub Articles Ahead of Print

A Divide-and-Conquer Strategy for the Prediction of Protein Contact Map
Cosme E. Santiesteban-Toca, Gerardo M. Casanola-Martin and Jesus S. Aguilar-Ruiz
View Abstract Purchase Online
Non-Classical Therapeutic Approach in the Treatment of Alzheimer's Disease: A Mini Review
Vladan Bajic, Biljana Spremo-Potparevic, Lada Zivković, Emina Sudar, Sonja Zafirovic, Milan Obradovic and Esma R. Isenovic
View Abstract Purchase Online
Investigation of new Phenothiazine and Carbazole Derivatives as Potential Inhibitors of Human Farnesyltransferase
Gina-Mirabela Dumitriu, Alina Ghinet, Dalila Belei, Benoît Rigo, Philippe Gautret, Joelle Dubois and Elena Bicu
View Abstract Purchase Online
Synthesis, in Vitro and in Vivo Anticancer Activity of Hybrids of 3-Hydroxy-Indolin-2-one and 2, 3-Dihydroquinolin-4(1H)-one
Lei Zhang, Wen-Yun Li, Jing Wang, Juan Xia, Jing Gao and Qi-Zheng Yao
View Abstract Purchase Online
Mannich Base Derivatives as the Potential Candidates of Human Topoisomerase II Inhibitors
Huseyin Istanbullu, Muge Senarisoy, Ercin Erciyas and Zeki Topcu
View Abstract Purchase Online
Quantum-Chemical Study on the Thermodynamical Aspect of Competitive Inhibition of Ribonucleotide Reductase by Trans-Resveratrol, Trans-Piceatannol and Hydroxyurea
Krzysztof Eder, Damian Mikulski and Marcin Molski
View Abstract Purchase Online
Identification of Novel GSK1070916 Analogs as Potential Aurora B Inhibitors: Insights from Molecular Dynamics and MM/GBSA based Rescoring
Faraz Shaikh, Soumendranath Bhakat, Abhishek Thakur, Ashish Radadia, Mahmoud E. S. Soliman and Anamik Shah
View Abstract Purchase Online
Theoretical Modelling of Potential Chk1 Inhibitors
Pedro M.M. Araújo, Luís Pinto da Silva and Joaquim C.G. Esteves da Silva
View Abstract Purchase Online
Design, Synthesis and Cytotoxic Evaluation of Novel Imatinib Amide Derivatives that Target Abl Kinase
Ri-Sheng Yao, Qiu-Xiang Guan, Xiao-Qin Lu and Ban-Feng Ruan
View Abstract Purchase Online
Pd/C-Catalyzed Synthesis of (E)-2-Arylmethylideneindolin-3-ols under Ultrasound: Their Initial Evaluation as Potential Anti-Proliferative Agents
Ponugubati Radhakrishna Murthi, Namburi Suresh, Chekuri Sharmila, Rani, Mandava Venkata Basaveswara Rao and Manojit Pal
View Abstract Purchase Online
Design, Synthesis and Antimycobacterial Activity of some new Azaheterocycles: Phenanthroline with p-halo-Benzoyl Skeleton. Part V
Ramona Danac, Teofil Daniloaia, Vasilichia Antoci and Ionel I. Mangalagiu
View Abstract Purchase Online
Alzheimer's Disease Prevention and use of Traditional Plant Medicines
Xiaogang Wang, Raphael Dubois and James David Adams
View Abstract Purchase Online
A Screening Method for Potential Anti-Pancreatic Cancer Candidate Compounds Based on Hsp90-Cdc37 Interaction Model in vitro
Hai Zhang, Sen Sun, Qingshan Chen, Guoqing Zhang, Zhenqing Zhang, Duxin Sun and Wenpeng Zhang
View Abstract Purchase Online
Design, Synthesis and Biological Evaluation of Benzimidazole-Pyridine-Piperidine Hybrids as a new class of potent Antimicrobial Agents
Kothapally Beulah, Akula Ravi Kumar, Boddupally Peda Venkat Lingaiah, Pamulaparthy Shanthan Rao, Banda Narsaiah, Aaramadaka Sunil Kumar Reddy and Upadhyayula Surya Narayana Murty
View Abstract Purchase Online
Design, Synthesis and Antitubercular Evaluation of New 2-Amino-5-(4-(Benzyloxy)Benzyl) Thiophene-3-Carboxylic Acid Derivatives. Part 3
Xiaoyun Lu, Jian Tang, Qidong You, Baojie Wan and Scott G. Franzblau
View Abstract Purchase Online
Structure Based Functional Annotation of Putative Conserved Proteins from Treponema Pallidum: Search for a Potential Drug Target
Avni Sinha, Faizan Ahmad and Md. Imtaiyaz Hassan
View Abstract Purchase Online
Design, Synthesis and AntitumorActivities of Bis-arylureas and Bisarylamides Based on 1H-benzo[d]imidazole Moiety as Novel BRaf V600E/VEGFR2 Dual Inhibitors
Weimin Yang, Yadong Chen, Yanmin Zhang, Sanzhi Tang, Hongli Chen, Weifang Tang and Tao Lu
View Abstract Purchase Online
Synthesis and Analgesic Activity of 3, 7-Dimethylpurine-2, 6-Dion-1-yl Derivatives of Acetic and Butanoic Acid
Malgorzata Zygmunt, Pawel Zmudzki, Grazyna Chlon-Rzepa, Jacek Sapaa and Maciej Pawlowski
View Abstract Purchase Online
Pd/C-Mediated Synthesis of 3-Methyleneisoindolin-1-ones: Biological and Theoretical Study of their PDE4 Inhibition
Suryadevara Vijayavardhini, Dandela Rambabu, Vegendla Radha, Ravikumar Kapavarapu, Mandava Venkata Basaveswara Rao and Manojit Pal
View Abstract Purchase Online
Synthesis and Evaluation of Bis-pyrazolineDerivatives as Potential Antimicrobial Agents
Mehlika Dilek Altıntop, Usama Abu Mohsen, Hulya Karaca, Zerrin Cantürk and Ahmet Ozdemir
View Abstract Purchase Online
The Inhibition of Acetylshikonin on Bacteria and their Trypsin-like Protease and Glycosidic Enzyme may be Essential to conquer periodontal Ecological Niche
Ming-Yu Li, Laikuan Zhu, Guang-Yun Lai, Sisu Mo and Jun Wang
View Abstract Purchase Online
Structural Characterization, Homology Modeling and Docking Studies of ARG674 Mutation in MyH8gene Associated with Trismus-Pseudocamptodactyly Syndrome
Munazzah Tasleem, Romana Ishrat, Asimul Islam, Faizan Ahmad and Md. Imtaiyaz Hassan
View Abstract Purchase Online
Design, Synthesis and in vitro Cytotoxicity Evaluation of new 3', 4'-bis (3, 4, 5-Trisubstituted)-4'H-Spiro [Indene-2, 5'-Isoxazol]-1(3H)-one Derivatives as Promising Anticancer Agents
Hoda Abolhasani, Afshin Zarghi, Ahmad Abolhasani, Maryam Hamzeh-Mivehroud, Nasrin Bargahi, Behrouz Notash, Javid Shahbazi Mojarrad and Siavoush Dastmalchi
View Abstract Purchase Online
Synthesis of Salicylic Acid-Based 1, 3, 4-Oxadiazole Derivatives Coupled with Chiral Oxazolidinones: Novel Hybrid Heterocycles as Antitumor Agents
M. S. R. Murty, Raju Penthala, Lekshmi R. Nath and Ruby John Anto
View Abstract Purchase Online
Synthesis and Cholinesterase Inhibition Activity of new Pyrrolopyrimidine Derivatives
Rangaswamy Roopashree, Toreshettahally Ramesh Swaroop, Swamy Jagadish, Chakrabhavi Dhananjaya Mohan and Kanchugarakoppal Subbegowda Rangappa
View Abstract Purchase Online
Synthesis, Structure-Activity Relationship (SAR) Studies on some 4-Aryl-4H-chromenes and Relationship between Lipophilicity and Antitumor Activity
Ahmed M. El-Agrody, Essam Shawky A. E. H. Khattab and Ahmed M. Fouda
View Abstract Purchase Online
Development of 1, 3 Benzothiazol-2-yl Hydrazine Derivatives Containing Semicarbazone and Thioamide Pharmacohphore as Anticonvulsants
Ruhi Ali and Nadeem Siddiqui
View Abstract Purchase Online
Synthesis and Evaluation of Transdermal Permeation, Pharmacological Activity of Bornyl NSAID Esters
Jiufeng Lin, Kefeng Ni, Yang Zhang, Dongzhi Wei and Yuhong Ren
View Abstract Purchase Online
Synthesis and Biological Activity of Thiazole Dithiocarbamate Derivatives
Nalan Gundogdu-Karaburun
View Abstract Purchase Online
Synthesis and Anticancer Activity of Some 2-[3/4-(2-Substituted Phenyl-2- oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one Derivatives
Nalan Gundogdu-Karaburun, Ahmet Cagri Karaburun, Seref Demirayak, Ismail Kayagil and Leyla Yurttas
View Abstract Purchase Online
Synthesis and Biological Evaluation of New Tubulin Inhibitors: Shikonin Thio-glycoside Derivatives
Xiao-Ming Wang, Hong-Yan Lin, Jin-Liang Qi, Li-Fei Bai and Yong-Hua Yang
View Abstract Purchase Online
Fat-Soluble Vitamins Release Based on Clinoptilolite Zeolite as an Oral Drug Delivery System
Mehdi Rahimi, Hamid Mobedi, Aliasghar Behnamghader, Alireza Nateghi Baygi, Houri Mivehchi and Esmaeil Biazar
View Abstract Purchase Online
Synthesis and Biological Evaluations of 3-Benzothiazol-2-yl Coumarin Derivatives as MEK1 Inhibitors
Chao Wang, Fengrong Xu, Yan Niu, Yun Wu, Jing Sun, Yihong Peng, Lei Liang and Ping Xu
View Abstract Purchase Online
Synthesis and Biological Evaluation of Arylthiourea Derivatives with Antitubercular Activity
Rusong Luo, Tuomo Laitinen, Liyan Teng, Tapio Nevalainen, Maija Lahtela-Kakkonen, Baofu Zheng, Honghai Wang, Antti Poso and Xuelian Zhang
View Abstract Purchase Online
Synthesis and Antiproliferative Evaluation of Hybrids of Indolin-2-one and Quinazoline-4(3H)-one Linked via Imine Bond
Wei-Yao Wu, Sheng-Li Cao, Bei-Bei Mao, Ji Liao, Zhong-Feng Li, Hao-Bin Song and Xingzhi Xu
View Abstract Purchase Online
Construction and High Expression of a Recombinant Amino-Proximal HSV-2 Glycoprotein B Polypeptide with Immunogenicity in Escherichia coli
Xu Ning, Tu Jingjing, Wang Xian Yan and Xu Fang
View Abstract Purchase Online
Synthesis and Study of Antitumor Activity of Artimisinin Glucoside
Yanrong Ren and Guoping Chen
View Abstract Purchase Online
Synthesis and Biological Activity of New 2,3-dihydro-1H-cyclopenta[b]- quinoline Derivatives as Acetylcholinesterase Inhibitors
Pawel Szymanski, Magdalena Markowicz, Marek Bajda, Barbara Malawska and Elzbieta Mikiciuk-Olasik
View Abstract Purchase Online
Novel Aminoalcohol Derivatives Bearing 4-Phenylphenol as Antischistosomal Drugs
Li-Ping Duan, Jian Xue, Yi Tao and Hao-Bing Zhang
View Abstract Purchase Online
Deformable Surfactant Vesicles Loading Ammonium Glycyrrhizinate: Characterization and In Vitro Permeation Studies
Luisa Di Marzio, Carlotta Marianecci, Federica Rinaldi, Sara Esposito and Maria Carafa
View Abstract Purchase Online
Advertisement

Related Journals




Related eBooks




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science