E-Pub Articles Ahead of Print ::: Current Pharmaceutical Design

ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)

Volume 21, 42 Issues, 2015

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Current Pharmaceutical Design

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E-Pub Articles Ahead of Print

Editorial: The Pathogenesis of Inflammation and Cancer in the Gastrointestinal Tract: From Basic Science to Translational Medicine
C.H. Cho and H.Y. Wang
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Potential of Peptide-Based Enhancers for Transdermal Delivery
Luciana B. Lopes, Vanessa F.M. Carvalho and Débora P. de Lemos
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Nanocarriers and their Actions to Improve Skin Permeability and Transdermal Drug Delivery
Nauman Rahim Khan, Mohd Saufi Harun, Asif Nawaz, Nurulaini Harjoh and Tin Wui Wong
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Overcoming the Skin Permeation Barrier: Challenges and Opportunities
Carla Vitorino, João Sousa and Alberto Pais
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Breaking the Skin Barrier: Achievements and Future Directions
Hui Zhang, Yingjie Zhai, Xiaoye Yang and Guangxi Zhai
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Recent Developments in Skin Mimic Systems to Predict Transdermal Permeation
L. J. Waters
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Supersaturation as a Tool for Skin Penetration Enhancement
Francesco Cilurzo, Antonella Casiraghi, Francesca Selmin and Paola Minghetti
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Cutaneous Delivery of Natural Antioxidants: the Enhancement Approaches
Ibrahim A. Aljuffali, Ching-Yun Hsu, Yin-Ku Lin and Jia-You Fang
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Vesicular Carriers for Skin Drug Delivery: The Pheroid™ Technology
Dewald Kilian, Yasser Shahzad, Lizelle Fox, Minja Gerber and Jeanetta Du Plessis
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Current Pharmaceutical Design on Adhesive Based Transdermal Drug Delivery Systems
Animesh Ghosh, Subham Banerjee, Santanu Kaity and Tin Wui Wong
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Dendritic Nanoparticles for CutaneousDrug Delivery -Testing in Human Skin and Reconstructed Human Skin
Christian Zoschke, Priscila Schilrreff, Eder L. Romero, Johanna M. Brandner and Monika Schäfer-Korting
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A Review of Polymeric Colloidal Nanogels in Transdermal Drug Delivery
Simphiwe Mavuso, Thashree Marimuthu, Yahya E. Choonara, Pradeep Kumar, Lisa C. du Toit and Viness Pillay
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Lipid Nanoparticles For Dermal Drug Delivery
Pratibha G. Kakadia and Barbara R. Conway
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Recent Advances in Physical Delivery Enhancement of Topical Drugs
Anthony P Raphael, Olivia RL Wright, Heather A Benson and Tarl W Prow
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Enhancing Topical Analgesic Administration: Review and Prospect for Transdermal and Transbuccal Drug Delivery Systems
Roser Sanz, Ana C. Calpena, Mireia Mallandrich and Beatriz Clares
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Proniosomes in Transdermal Drug Delivery
Yahya Rahimpour, Maryam Kouhsoltani and Hamed Hamishehkar
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Topical Delivery Of Drugs For The Effective Treatment Of Fungal Infections Of Skin
Nida Akhtar, Anurag Verma and Kamla Pathak
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Efficacy of Andolast in Mild to Moderate Asthma: A Randomized, Controlled, Double-Blind Multicenter Study (The Andast Trial)
Mario Malerba, Massimo D`Amato, Alessandro Radaeli, Giampaolo Giacovelli, Lucio Rovati, Sayed H. Arshad and Stephen T. Holgate
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Editorial: Breaking the Skin Barrier: Achievements and the Future
Yasser Shahzad
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Atrial Fibrillation and Gastro-Oesophageal Reflux Disease - Controversies and Challenges
Mariana Floria, Oana Bărboi, Ciprian Rezuș, Valentin Ambărus, Cristina Cijevschi-Prelipcean, Gheorghe Balan and Vasile Liviu Drug
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MicroRNAs in Esophageal Adenocarcinoma: Functional Significance and Potential for the Development of New Molecular Disease Markers
Yuri V. Bobryshev, Alexander N. Orekhov and Dmitry A. Chistiakov
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Predicting the Druggability of Protein-Protein Interactions Based on Sequence and Structure features of active pockets
X u Dai, Run Yu Jing, Yanzhi Guo, Yong Cheng Dong, Yue Long Wang, Yuan Liu, Xue Mei Pu and Menglong Li
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Anti-VEGF Drugs in Eye Diseases: Local Therapy with Potential Systemic Effects
Markus van der Giet, Cornelia Henkel, Mirjam Schuchardt and Markus Tölle
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The Potential Effect of Fluorinated Compounds in the Treatment of Alzheimer’s Disease
Bárbara Gomes, Joana A. Loureiro, Manuel A.N. Coelho and Maria do Carmo Pereira
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Anticancer Advances of Matrine and Its Derivatives
Jianping Yong, Xiaoyuan Wu and Canzhong Lu
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Skeletal Muscle Cell Behavior After Physical Agent Treatments
Michela Battistelli, Sara Salucci, Michele Guescini, Davide Curzi, Vilberto Stocchi and Elisabetta Falcieri
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Analysis of Edg-Like LPA Receptor-Ligand Interactions
Balazs Balogh, Tamas Pazmany and Peter Matyus
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Multiple Roles of Fibroblast Growth Factor 21 in Metabolism
Li Li and Liling Tang
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Evaluation of the In Vivo Safety Profiles of Rictor Inhibition Using a Zebrafish Model
Yang Cao, Lijun Jiang, Lei Zhao, Xiaoxi Zhou, Na Wang, Peilin Zhang, Yuting Tang and Jianfeng Zhou
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Applications of Important Polysaccharides in Drug Delivery
Gangliang Huang, Xinya Mei, Feng Xiao, Xin Chen, Qilin Tang and Daquan Peng
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The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs
Feng Wang, Junsheng Lin and Ruian Xu
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Editorial: Mitochondrial Biogenesis: Pharmacological Approaches
Teresa Valero
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Mechanisms of Inflammatory Response and Organ Dysfunction: Organ-Protective Strategy by Anesthetics
Noboru Hatakeyama and Naoyuki Matsuda
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VEGF and Colon Cancer Growth Beyond Angiogenesis: Does VEGF Directly Mediate Colon Cancer Growth Via a Non-angiogenic Mechanism?
Amrita Ahluwalia, Michael K. Jones, Tamara Matysiak-Budnik and Andrzej S. Tarnawski
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The Impact of Computational Structure-Based Methods on Drug Discovery
Charles H. Reynolds
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Anti-miRNA-23a Oligonucleotide Suppresses Glioma Cells Growth by Targeting Apoptotic Protease Activating Factor-1
Shizhong Lian, Ruyi Shi, Tao Bai, Yang Liu, Wang Miao, Hongqin Wang, Xiaodong Liu and Yimin Fan
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Editorial: The SNAP-tag Technology – A Versatile Tool with many Applications
Stefan Barth
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Gender Based Differences in Stress-induced Gastric Ulcer Formation and its Regulation by Nitric Oxide (NO): An Experimental Study
Kavita Gulati, Ayanabha Chakraborti and Arunabha Ray
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Differential Influences of Gastric Bypass and Sleeve Gastrectomy on Plasma Nesfatin-1 and Obestatin Levels in Patients with Type 2 Diabetes Mellitus
Wei-Jei Lee, Chih-Yen Chen, Kong-Han Ser, Keong Chong, Shu-Chun Chen, Pui-Ching Lee, You-Di Liao and Shou-Dong Lee
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Probiotics for the Prevention and Treatment of Allergies, with an Emphasis on Mode of Delivery and Mechanism of Action
Satya Prakash, Catherine Tomaro-Duchesneau, Shyamali Saha, Laetitia Rodes, Imen Kahouli and Meenakshi Malhotra
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Consumption of Mixed Fruit-juice Drink and Vitamin C Reduces Postprandial Stress Induced by a High Fat Meal in Healthy Overweight Subjects
Ilaria Peluso, Debora V. Villano, Susan A. Roberts, Eleonora Cesqui, Anna Raguzzini, Gina Borges, Alan Crozier, Giovina Catasta, Elisabetta Toti and Mauro Serafini
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Immunomodulating and Anti-allergic Effects of Negroamaro and Koshu Vitis vinifera Fermented Grape Marc (FGM)
Giuseppe Marzulli, Thea Magrone, Luisa Vonghia, Masahiro Kaneko, Hiroaki Takimoto, Yoshio Kumazawa and Emilio Jirillo
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Potential Use of Dietary Natural Products, Especially Polyphenols, for Improving Type-1 Allergic Symptoms
Kumazawa Y, Takimoto H, Matsumoto T and Kawaguchi K
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Omega-6 and Omega-3 Polyunsaturated Fatty Acids and Allergic Diseases in Infancy and Childhood
Elizabeth A. Miles and Philip C. Calder
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Factors Affecting Residual Platelet Aggregation in Prasugrel Treated Patients
Dimitrios Alexopoulos, Ioanna Xanthopoulou, Angelos Perperis, Argyro Siapika, Katerina Stavrou, Evropi Tsoni, Periklis Davlouros and George Hahalis
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What Fans the Fire: Insights into Mechanisms of Leptin in Metabolic Syndrome- Associated Heart Diseases
Maolong Dong and Jun Ren
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Transactivation of ErbB Receptors by Leptin in the Cardiovascular System: Mechanisms, Consequences and Target for Therapy
Jerzy Bełtowski and Anna Jazmroz-Wiśniewska
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Structural Insights into Chitinolytic Enzymes and Inhibition Mechanisms of Selective Inhibitors
Tian Liu, Lei Chen, Qiang Ma, Xu Shen and Qing Yang
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Structure-based Design of Conformationally Flexible Reverse Transcriptase Inhibitors to Combat Resistant HIV
Ge-Fei Hao, Sheng-Gang Yang and Guang-Fu Yang
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Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement
Lothar Esser, Chang-An Yu and Di Xia
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ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development
Young Hee Choi, Ai-Ming Yu and Ai-Ming Yu
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Structure-Based Drug Design to Overcome Drug Resistance: Challenges and Opportunities
Rafaela S. Ferreira1, Adriano D. Andricopulo and Adriano D. Andricopulo
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Novel Next-Generation Sequencing and Networks-Based Therapeutic Targets: Realistic and More Effective Drug Design and Discovery
Dimitrios H. Roukos, Giannis G. Baltogiannis, Christos S. Katsouras, Aris Bechlioulis, Katerina K. Naka, Charalambos Batsis, Theodore Liakakos and Lampros K. Michalis
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Endothelial Dysfunction and the Effects of TNF Inhibitors on the Endothelium in Psoriasis and Psoriatic Arthritis: A Systematic Review
Elizabeth A. Brezinski, Matthew R. Follansbee, Ehrin J. Armstrong and April W. Armstrong
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Effects of Biologic Agents and Other Disease-Modifying Antirheumatic Drugs on Cardiovascular Outcomes in Psoriasis and Psoriatic Arthritis: A Systematic Review
April W. Armstrong, Elizabeth A. Brezinski, Matthew R. Follansbee and Ehrin J. Armstrong
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Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents
Yan Lin, Zhi-Yi Chen and Feng Yang
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Long-term Etanercept Therapy Favors Weight Gain and Ameliorates Cachexia in Rheumatoid Arthritis Patients: Roles of Gut Hormones and Leptin
Chih-Yen Chen, Chang-Youh Tsai, Pui-Ching Lee and Shou-Dong Lee
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The Effect of First-in-Class Small Molecule RhoA Inhibitor, HL07, on the Phenylephrine-induced Artery Contraction
Yan Zhang, Jing Deng, Sheng Ma, Lin Xue, Jin Zhu, Wei-liang Zhu, Hua-liang Jiang, Jian Li and Li-yan Miao
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Non-Systemic Drugs: A Critical Review
Dominique Charmot
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Advancement of Targeted Ultrasound Contrast Agents and their Applications in Molecular Imaging and Targeted Therapy
Feng Yang, Zhi-Yi Chen and Yan Lin
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Atorvastatin Sensitises Vascular Smooth Muscle Cells, but not Endothelial Cells, to TNF-α-induced Cell Death
Arturo Giordano, Simona Romano, Giovanna Nappo, Stefano Messina, Michele Polimeno, Nicola Corcione, Gaetano Calì, Paolo Ferraro, Mario Monaco, Nicola Zambrano and Maria Fiammetta Romano
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Carotenoids and Cardiovascular Risk
Paola Giordano, Pietro Scicchitano, Manuela Locorotondo, Cosimo Mandurino, Gabriella Ricci, Santa Carbonara, Michele Gesualdo, Annapaola Zito, Annamaria Dachille, Paola Caputo, Roberta Riccardi, Giulia Frasso, Giuseppe Lassandro, Antonio Di Mauro and Marco Matteo Ciccone
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A Computational Study of the Oligosaccharide Binding Sites in the Lectin-Like Domain of Tumor Necrosis Factor and the TNF-derived TIP Peptide
Alexander Dulebo, Rüdiger Ettrich, Rudolf Lucas and David Kaftan
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Target-based Anti-angiogenic Therapy in Breast Cancer
Markus Wehland, Johann Bauer, Manfred Infanger and Daniela Grimm
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Preclinical Safety and Pharmacokinetic Profile of 3K3A-APC, a Novel, Modified Activated Protein C for Ischemic Stroke
Patricia D. Williams, Berislav V. Zlokovic, John H. Griffin, Kent E. Pryor and Thomas P. Davis
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