E-Pub Articles Ahead of Print ::: Current Pharmaceutical Design

ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 23, 46 Issues, 2017


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Current Pharmaceutical Design

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Articles Ahead of Print

Effect of Magnesium Supplementation on Plasma C-reactive Protein Concentrations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials


Luis E. Simental-Mendía, Amirhossein Sahebkar, Martha Rodríguez-Morán, Graciela Zambrano-Galván and Fernando Guerrero-Romero


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Formulation, Quality Control and Safety Issues of Nanocarriers Used for Cancer Treatment


Ismael D. Bianco, Marcelo R. Ceballos, Cristian Casado, Viviana G. Dabbene, Carolina Rizzi and R. Kiyomi Mizutamari


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Management of Blood Pressure and Heart Rate in Patients with Diabetes Mellitus


Ioanna Gouni-Berthold, Ruth Hanssen, Lisa Ravarani and Heiner K. Berthold


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What is the Real Efficacy of Beta-Blockers for the Treatment of Essential Hypertension?


Christian Höcht, Facundo M Bertera, Julieta S Del Mauro, Yanina Santander Plantamura, Carlos A Taira and Ariel H Polizio


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The “Neurocentric” Approach to Essential Hypertension: How Reliable is the Paradigm of Hyperkinetic Hypertension? A Focus on the Sympathetic Nervous System Dysregulation in Essential Hypertensive Patients with Elevated Resting Heart Rate


Domenico Di Raimondo, Gaia Musiari, Mauro Grova, Giuseppe Miceli, Antonino Tuttolomondo and Antonio Pinto


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Polymeric Nanocarriers: A New Horizon for the Effective Management of Breast Cancer


Iliyas Khan, Hitesh Kumar, Gaurav Mishra, Avinash Gothwal, Prashant Kesharwani and Umesh Gupta


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Management of Blood Pressure and Heart Rate in Chronic Kidney Disease


Antonia Kaltsatou


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Hybrid Polymeric-Magnetic Nanoparticles in Cancer Treatments


Alexandra Muñoz Bonilla and Pilar Herrasti González


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Supramolecular Self-Assembled Nanogels a New Platform for Anticancer Drug Delivery


Jaleh Varshosaz, Somayeh Taymouri and Erfaneh Ghassami


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Modulation of Heart Rate by Acute or Chronic Aerobic Exercise. Potential Effects on Blood Pressure Control


Carme Perez-Quilis, J. Derek Kingsley, Kabir Malkani, Gianfranco Cervellin, Giuseppe Lippi and Fabian Sanchis-Gomar


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Zein-based Nanocarriers as Potential Natural Alternatives for Drug and Gene Delivery: Focus on Cancer Therapy


Ahmed Elzoghby, May Freag, Hadeer Mamdouh and Kadria Elkhodairy


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Albumin Nanocarriers, γ - Irradiated Crosslinked, Combined with Therapeutic Drugs for Cancer Therapy


Macarena Siri, Estefanía Achilli, Mariano Grasselli and Silvia del V. Alonso


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Using Properties of Tumor Microenvironments for Controlling Local, On-Demand Delivery from Biopolymer-Based Nanocarriers


Abdullah K. Alshememry, Suleiman S. El-Tokhy and Larry D. Unsworth


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A Special Focus on Selexipag - Treatment of Pulmonary Arterial Hypertension


Louise Marqvard Sørensen, Markus Wehland, Marcus Krüger, Ulf Simonsen, Mohamed Zakaria Nassef, Manfred Infanger and Daniela Grimm


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Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications


Swathi Putta, Ilaria Peluso, Nagendra Sastry Yarla, Eswar Kumar Kilari, Anupam Bishayee, Da-Yong Lu, George E. Barreto, Ghulam Md Ashraf, Luciana Scotti, Marcus T. Scotti, Rajeev K. Singla, Thonos Alexiou, Atanas G. Atanasov, Vadim V. Tarasov, P. Veera Bramhachari, Sarat Babu Imandi, Madhuri Chintala, Bechan Sharma, Marcella Reale, Rosanna Filosa, Gjumrakch Aliev and Mohammad Amjad Kamal


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Optimal Pre-treatment for Acute Exposure to the Organophosphate Dicrotophos


Dietrich E. Lorke, Syed M. Nurulain, Mohamed Y. Hasan, Kamil Kuča and Georg A. Petroianu


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Editorial: Recent Advances in the Field of Kinases and Kinase Inhibitors


Zunnan Huang and Mee-Hyun Lee





Ketogenic Diets in the Treatment of Epilepsy


Maurizio Elia, Joerg Klepper, Baerbel Leiendecker and Hans Hartmann


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Management of Antiepileptic Treatment After Epilepsy Surgery - Practices and Problems


Guido Rubboli, Anne Sabers, Peter Uldall and Kristina Malmgren


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Antiepileptic Treatments in Developing Countries


Jeremy Jost, Athanase Millogo and Pierre-Marie Preux


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Treatment of Epileptic Encephalopathies


Simona Balestrini and Sanjay M Sisodiya


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Protein Kinases as Tumor Biomarkers and Therapeutic Targets


Chuntao Quan, Juanjuan Xiao, Lin Liu, Qiuhong Duan, Ping Yuan and Feng Zhu


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Application of Kinase Inhibitors for Anti-Aging Intervention


Mercedes Cano, Antonio Ayala, Francesco Marotta and Sandro Argüelles


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GSK3 Inhibitors in the Therapeutic Development of Diabetes, Cancer and Neurodegeneration: Past, Present and Future


Mudasir Maqbool and Nasimul Hoda


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Targeting Protein Kinases for the Treatment of Glioblastoma Multiforme: Linking Basic Studies to Clinical Applications


Aidong Zhou


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Protein Kinase Inhibitors as Potential Antimicrobial Drugs Against Tuberculosis, Malaria and HIV


Yong Cheng, Jeffrey S. Schorey, Cheng-Cai Zhang and Xuejuan Tan


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The Role of Exosomes and Exosome-derived microRNAs in Atherosclerosis


Xinjie Lu


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Implications of Photophysical and Physicochemical Factors on Successful Application of Photodynamic Therapy


Shubhajit Paul, Paul Wan Sia Heng and Lai Wah Chan


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Pivotal Roles of Interleukin-17 as the Epicenter of Bone Loss Diseases


Chongshan Liao, Chengfei Zhang and Yanqi Yang


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Nanotechnology in Neurosciences: An Approach


Rosa Helena Bustos, M. Magdy Sanchez, Maria Andrea Dominguez-Sanchez, George E. Barreto, Daniel Lancheros and Jorge Reynolds


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Biotin and Glutathione Targeting of Solid Nanoparticles to Cross Human Brain Endothelial Cells


Szilvia Veszelka, Mária Mészáros, Lóránd Kiss, Zoltán Kóta, Tibor Páli, Zsófia Hoyk, Zsolt Bozsó, Lívia Fülöp, András Tóth, Gábor Rákhely and Mária A. Deli


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Epigenetics of Virus-Induced Tumors: Perspectives for Therapeutic Targeting


Svetlana Vinokurova


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Neuroglial Cell Cryopreservation in Appropriate Inductive Conditions


Rosa M. Gomez, Maria Andrea Dominguez-Sanchez, Magdy M. Sanchez and George E. Barreto


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Role of the Immune Component of Tumor Microenvironment in the Efficiency of Cancer Treatment: Perspectives for the Personalized Therapy


Marina Stakheyeva, Vladimir Riabov, Irina Mitrofanova, Nikolai Litviakov, Evgeny Choynzonov, Nadezhda Cherdyntseva and Julia Kzhyshkowska


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DNA Base Excision Repair: The Achilles’ Heel of Tumour Cells and their Microenvironment


M Poletto , A J Legrand and G L Dianov


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Identification of Antineoplastic Targets with Systems Approaches, Using Resveratrol as an In-Depth Case Study


Nivedita Singh, Sherry Freiesleben, Shailendra K. Gupta, Yogeshwer Shukla and Olaf Wolkenhauer


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Always Look On the Bright Side: Anti-Tumor Functions of Neutrophils


Sandra Völs, Ronit Vogt Sionov and Zvi Granot


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Membrane-bound ATP-dependent Energy Systems, as Extra- and Intracellular Key Signals for Gastrointestinal Functions and their Regulations in the Gastrointestinal Mucosa


Gyula Mózsik, Imre László Szabó and József Czimmer


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Modulation of GABAA Receptors in the Treatment of Epilepsy


Eleonora Palma, Gabriele Ruffolo, Pierangelo Cifelli, Cristina Roseti, Erwin A. van Vliet and Eleonora Aronica


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Update on Pharmacological Treatment of Progressive Myoclonus Epilepsies.


Edoardo Ferlazzo, Dorothee Kasteleijn-Nolst Trenite, Gerrit-Jan de Haan, Felix Felix Nitschke, Saija Ahonen, Sara Gasparini and Berge A. Minassian


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Antiepileptic Drugs in Clinical Development: Differentiate or Die?


Gaetano Zaccara and D. Schmidt


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Safety Profile of the Newest Antiepileptic Drugs: A Curated Literature Review


Caterina Palleria, Giuseppe Cozza, Rajeshree Khengar, Vincenzo Libri and Giovambattista De Sarro


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Protein Kinases as Targets for Opisthorchis viverrini- Associated Cholangiocarcinoma Therapy


Watcharin Loilome and Hasaya Dokduang


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Discovery and Development of ATP-Competitive mTOR Inhibitors Using Computational Approaches


Yao Luo and Ling Wang


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Induction of Synthetic Lethality by Natural Compounds Targeting Cancer Signaling


Lee Farrand and Sanguine Byun


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Protein Tyrosine Signaling and its Potential Therapeutic Implications in Carcinogenesis


Mihwa Kim, Minwoo Baek and Dae Joon Kim


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Nano-sized Ultrasound Contrast Agents for Cancer Therapy and Theranostics


Hao Li, Shenglong Gan, Shi-Ting Feng, Guofu Zhou, Zhi Dong, Rongqin Zheng and Zi-Ping Li


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Potentially Clinically Relevant Pharmacodynamic Interactions Between Antiepileptic Drugs and Psychotropic Drugs: An Update


Edoardo Spina and Jose de Leon


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The Relevance of Post-Transcriptional Mechanisms in HIV Latency Reversal


Ambra Sarracino and Alessandro Marcello


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Targeting CD147 is a Novel Strategy for Antitumor Therapy


ChengXiang Lian, Yeye Guo, Jianglin Zhang, Xiang Chen and Cong Peng


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The HIV-1 Tat Protein: Mechanism of Action and Target for HIV-1 Cure Strategies


Andrew P. Rice


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Protein Phosphatase-1 –targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals


Xionghao Lin, Tatyana Ammosova, Namita Kumari and Sergei Nekhai


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Dual Roles of Pin1 in Cancer Development and Progression


Hyeong-jun Han, Bu Young Choi and Young-Joon Surh


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Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription


Guillaume Mousseau and Susana T. Valente


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HIV-1 Transcription Inhibitors Increase the Synthesis of Viral Non-Coding RNA that Contribute to Latency


Yao A. Akpamagbo, Catherine DeMarino, Michelle L. Pleet, Angela Schwab, Myosotys Rodriguez, Robert A. Barclay, Gavin Sampey, Sergey Iordanskiy, Nazira El-Hage and Fatah Kashanchi


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Management of Blood Pressure and Heart Rate in Patients with Acute Stroke


Carlo Maida, Antonino Tuttolomondo, Domenico Di Raimondo and Antonio Pinto


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Molecular Targeting of ERKs/RSK2 Signaling in Cancers


Yong-Yeon Cho


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The Lipid-Lowering Effects and Associated Mechanisms of Dietary Phytosterol Supplementation


Jerad H Dumolt and Todd C Rideout


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Biomaterials and Supercritical Fluid Technologies: Which Perspectives to Fabricate Artificial Extracellular Matrix?


Della Porta Giovanna, E. Reverchon and N. Maffulli


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Current and Emerging Strategies in Osteoporosis Management


Stefka Ivanova and Liliya Vasileva


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Hydrogel-Based Cell Therapies for Kidney Regeneration: Current Trends in Biofabrication and In Vivo Repair


Katja Jansen, Carl C.L. Schuurmans, Jitske Jansen, Rosalinde Masereeuw and Tina Vermonden


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Hybrid Materials and Nanocomposites as Multifunctional Biomaterials


Heveline D. M. Follmann, Alliny F. Naves, Rafael A. Araujo, Viktor Dubovoy, Xiaoxi Huang, Tewodros Asefa, Rafael Silva and Osvaldo N. Oliveira


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Biohybrid Membrane Systems for Testing Molecules and Stem Cell Therapy in Neuronal Tissue Engineering


Sabrina Morelli, Antonella Piscioneri, Simona Salerno, Enrico Drioli and Loredana De Bartolo


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Effects of Oral and Non-Insulin Injectable Antidiabetic Treatment in Hypertension: A Systematic Review


Vasiliki Katsi, Georgios Georgiopoulos, Georgia Vogiatzi, Dimitrios Oikonomou, Maria Megapanou, John Skoumas, Charalampos Vlachopoulos, Petros Nihoyannopoulos and Dimitris Tousoulis


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The Role of Stress in Inflammatory Bowel Diseases


Dolores Sgambato, Agnese Miranda, Rocco Ranaldo, Alessandro Federico and Marco Romano


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Molecular Tests for the Choice of Cancer Therapy


Anna P. Sokolenko and Evgeny N. Imyanitov


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Recent Advances in the Function of the 67 kDa Laminin Receptor and its Targeting for Personalized Therapy in Cancer


Ada Pesapane, Pia Ragno, Carmine Selleri and Nunzia Montuori


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Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery


Trevor Clancy, Ruth Dannenfelser, Olga Troyanskaya, Karl Johan Malmberg, Eivind Hovig and Vessela Kristensen


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Vitamins in Heart Failure: Friend or Enemy?


George Georgiopoulos, Christina Chrysohoou, Georgia Vogiatzi , Nikolaos Magkas, Ippokratis Bournelis, Sofia Bampali, Damien Gruson and Dimitris Tousoulis


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Aquaporin 4 in Astrocytes is a Target for Therapy in Alzheimer's Disease


Yu-Long Lan, Jian-Jiao Chen, Gang Hu, Jun Xu, Ming Xiao and Shao Li


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AMPK: Therapeutic Target for Diabetes and Cancer Prevention


Shotaro Umezawa , Takuma Higurashi and Atsushi Nakajima


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New Strategies for the Prevention and Treatment of Systemic and Local Bone Loss; from Pathophysiology to Clinical Application


A. Fassio, Maurizio Rossini , Ombretta Viapiana, Luca Idolazzi, Camilla Benini, Elisabetta Vantaggiato and Davide Gatti


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Gene Delivery with Organic Electronic Biomaterials


Kathryn Frances Anne Clancy and John George Hardy


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Altered Homeostatic Functions in Reactive Astrocytes and Their Potential as a Therapeutic Target After Brain Ischemic Injury


Helena Pivonkova and Miroslava Anderova


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Targeting Human Astrocytes’ Calcium-sensing Receptors for Treatment of Alzheimer’s Disease


Anna Chiarini, Ubaldo Armato, James F. Whitfield and Ilaria Dal Pra


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Astrocyte: An Innovative Approach for Alzheimer's Disease Therapy


Maria Rosanna Bronzuoli, Roberta Facchinetti, Luca Steardo and Caterina Scuderi


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Therapeutic Strategy of Targeting Astrocytes for Neuroprotection in Parkinson's Disease


Ikuko Miyazaki and Masato Asanuma


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Oncostatin M: Potential Implications for Malignancy and Metabolism


Jacqueline M. Stephens and Carrie M. Elks


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Emerging Targets to Relieve Fat Stress-Induced Liver Diseases: UDCA, Tocotrienol, ω-3 PUFAs, and IgY Targeted NPC1L1 Cholesterol Transporter


Ji-Young Cha, Jong-Min Park, Ho-Jae Lee, Jin-Sik Bae, Young-Min Han, Byung-Chul Oh, Kwang Hyun Ko and Ki-Baik Hahm


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Class A GPCRs: Structure, Function, Modeling and Structure-based Ligand Design


Xiaojing Cong, Jérémie Topin and Jérôme Golebiowski


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The Tat/P-TEFb Protein-Protein Interaction Determining Transcriptional Activation of HIV


Kaori Asamitsu and Takashi Okamoto


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Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) as a Target for Concurrent Management of Diabetes and Obesity-Related Cancer


Mustapha Umar Imam, Qingqing Wang, Zhang Yida and Fudi Wang


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PTEN, Insulin Resistance, and Cancer


Aiqing Li, Minzi Qiu, Hongbo Zhou, Tao Wang and Wen Guo


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Plasmodial Hsp40s: New Avenues for Antimalarial Drug Discovery


Michael O Daniyan and Gregory L Blatch


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Circadian MicroRNAs in Cardioprotection


Yoshimasa Oyama, Colleen Marie Bartman, Jennifer Gile and Tobias Eckle


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Recent Advances in Polymeric Nanosystems for Treating Cutaneous Melanoma and Its Metastasis


Yi-Ping Chou, Yin-Ku Lin, Chun-Han Chen and Jia-You Fang


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Protein Kinase Inhibitors as Therapeutic Drugs in AML: Advances and Challenges


Yuan Ling, Zikang Zhang, Hua Zhang and Zunnan Huang


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Sulfated Glycans in HIV Infection and Therapy


Vitor H. Pomin, Francisco F. Bezerra and Paulo A.G. Soares


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Potential Application of 5-Aryl-Substituted 2-Amino-benzamide Type of HDAC1/2- Selective Inhibitors to Pharmaceuticals


Shinichi Uesato, Yoshiyuki Hirata and Tsutomu Sasaki


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Role of Polyamines in Parasite Cell Architecture and Function


Marcos A. Vannier-Santos and Ana M. Suarez-Fontes


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Polyamine Transport and Synthesis in Trichomonas vaginalis: Potential Therapeutic Targets


María Elizbeth Alvarez-Sánchez, José Luis Villalpando, Laura Itzel Quintas-Granados and Rossana Arroyo


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Antidiabetic Drugs and the Kidney


Moses Elisaf, Eleftheria Tzavela, Nikolaos Karanatsis and Vasilis Tsimihodimos


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Targeting Astrocytes for Treating Neurological Disorders: Carbon Monoxide and Noradrenaline-Induced Increase in Lactate


Anemari Horvat, Nina Vardjan and Robert Zorec


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Post Mortem Redistribution of Drugs: Current State of Knowledge


Caroline Sastre, Christophe Bartoli, Valerie Baillif-Couniou, Georges Leonetti and Anne-Laure Pelissier-Alicot


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Functional Nanoparticles and their Interactions with Mesenchymal Stem Cells


Weiwei Wang, Zijun Deng, Xun Xu , Zhengdong Li, Friedrich Jung, Nan Ma and Andreas Lendlein


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Metallothionein is a Potential Therapeutic Strategy for Amyotrophic Lateral Sclerosis


Shin-ichi Ono


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Recent Advances on the Role of microRNAs in Both Insulin Resistance and Cancer


Adele Vivacqua, Paola De Marco, Antonino Belfiore and Marcello Maggiolini


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GLT-1 Upregulation as a Potential Therapeutic Target for Ischemic Brain Injury


Yu-Yan Hu, Li Li, Xiao-Hui Xian, Min Zhang, Xiao-Cai Sun, Shu-Qin Li, Xin Cui, Jie Qi and Wen-Bin Li


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Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis


Mariana Pehar, Benjamin A. Harlan, Kelby M. Killoy and Marcelo R. Vargas


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Trimethylamine N-oxide (TMAO) as a New Potential Therapeutic Target for Insulin Resistance and Cancer


Jens Oellgaard, Signe Abitz Winther, Tobias Schmidt Hansen, Peter Rossing and Bernt Johan von Scholten


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Application of Alphaviral Vectors for Immunomodulation in Cancer Therapy


Anna Zajakina, Karina Spunde and Kenneth Lundstrom


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Using β-Amino Acids and β-Peptide Templates to Create Bioactive Ligands and Biomaterials


Mark P Del Borgo, Ketav Kulkarni and Marie-Isabel Aguilar


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Chemokine Like Receptor- 1 (CMKLR-1) Receptor: A Potential Therapeutic Target in Management of Chemerin Induced Type 2 Diabetes Mellitus and Cancer


Sangeetha Perumalsamy, Nurul Ain Aqilah Mohd Zin, Riyanto Teguh Widodo, Wan Azman Wan Ahmad, Shireene Ratna DB Vethakkan and Hasniza Zaman Huri


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Astrocytes Pathology in ALS: A Potential Therapeutic Target?


Sonja Johann


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Targeting Astrocytes for Treatment in Amyotrophic Lateral Sclerosis


Mina Perić, Dinko Mitrečić and Pavle R. Andjus


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Hydroxyapatite as a Nanomaterial for Advanced Tissue Engineering and Drug Therapy


Juha Tuukkanen and Miho Nakamura


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Targeting the Tumor Microenvironment by Intervention in Interleukin-1 Biology


Elena Voronov and Ron N Apte


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Alginate-Based Cell Microencapsulation for Tissue Engineering and Regenerative Medicine


Vittoria Pandolfi, Ulysse Pereira, Murielle Dufresne and Cécile Legallais


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Tumor Reversion: Mesenchymal-Epithelial Transition as a Critical Step in Managing the Tumor-Microenvironment Cross-Talk


Mariano Bizzarri, Alessandra Cucina and Sara Proietti


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Obesity-Induced Hypertension: New Insights


Christina Antza, Stella Stabouli, Michalis Natsis, Ioannis Doundoulakis and Vasilios Kotsis


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Adiponectin as a Potential Therapeutic Target for Prostate Cancer


Hanuma Kumar Karnati, Manas Kumar Panigrahi, Yazhou Li, David Tweedie and Nigel H. Greig


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Effect of Intranasal Administration of Galanin-like Peptide (GALP) on Body Weight and Hepatic Lipids Accumulation in Mice with Diet-induced Obesity


Satoshi Hirako, Nobuhiro Wada, Haruaki Kageyama, Fumiko Takenoya, Hyounju Kim, Yuzuru Iizuka, Akiyo Matsumoto, Mai Okabe and Seiji Shioda


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From Tendon Injury to Collagen-Based Tendon Regeneration: Overview and Recent Advances


Clément Rieu, Lise Picaut, Gervaise Mosser and Léa Trichet


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Tissue Engineered Skin and Wound Healing: Current Strategies and Future Directions


Nandana Bhardwaj, Dimple Chouhan and Biman B. Mandal


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The Second-generation of Highly Potent Hepatitis C Virus (HCV) NS3/4A Protease Inhibitors: Evolutionary Design Based on Tailor-made Amino Acids, Synthesis and Major Features of Bio-activity


Shuni Wang, Yibing Wang, Jiang Wang, Tatsunori Sato, Kunisuke Izawa, Vadim A. Soloshonok and Hong Liu


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Engineered Bone Tissue with Naturally-Derived Small Molecules


Guleid Awale, Edgar Wong, Komal Rajpura and Kevin W.-H. Lo


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Therapeutic Potential of Heme Oxygenase-1/carbon Monoxide System Against Ischemia-reperfusion Injury


Yuanyuan Cheng and Jianhui Rong


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Hormones and Sarcopenia


John E. Morley


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Parasite Polyamines as Pharmaceutical Targets


Sigrid Roberts and Buddy Ullman


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Micro-RNA Profiling as a Predictor of Clinical Outcomes for Head and Neck Cancer Patients


Tatyana Isayeva, Margaret Brandwein-Gensler , Maheshika Somarathna , Lakisha D Moore-Smith and Timmy Lee


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Ion Channel and Neurotransmitter Modulators as Electroceutical Approaches to the Control of Cancer


Jack Tuszynski, Tatiana M. Tilli and Michael Levin


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The Chemo-Biological Outreach of Nano-Biomaterials: Implications for Tissue Engineering and Regenerative Medicine


Pradeep Kumar, Yahya E. Choonara, Riaz A. Khan and Viness Pillay


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Effect and Mechanism of Curcumin on EZH2 – miR-101 Regulatory Feedback Loop in Multiple Myeloma


Chuanqing Wu, Tuo Ruan, Weizhen Liu, Xiaojie Zhu, Juan Pan, Wen Lu, Chen Yan, Kaixiong Tao , Weikang Zhang and Chun Zhang


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Microbubbles: A Novel Strategy for Chemotherapy


Mu-hua Luo, Chih-Kuang Yeh, Bing Situ, Jin-sui Yu, Bing-cheng Li and Zhi-yi Chen


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Application of Bone Marrow Stem Cell Based Therapy in Bone Loss Diseases


Nan Xiao


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Self-Assembled Nanocarriers Based on Amphiphilic Natural Polymers for Anti- Cancer Drug Delivery Applications


Sally Sabra, Mona Abdelmoneem, Mahmoud Abdelwakil, Moustafa Taha Mabrouk, Doaa Anwar, Rania Mohamed, Sherine Khattab, Adnan Bekhit, Kadria Elkhodairy, May Freag and Ahmed Elzoghby


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Bone-Muscle Crosstalk: Unraveling New Therapeutic Targets for Osteoporosis


Anna Picca, Riccardo Calvani, Ester Manes-Gravina, Leonardo Spaziani, Francesco Landi, Roberto Bernabei and Emanuele Marzetti


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Hyaluronate-Lipid Nanohybrids: Fruitful Harmony in Cancer Targeting


May S Freag


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Micelles As Delivery System for Cancer Treatment


Dilek Keskin and Ayşen Tezcaner


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Management of Blood Pressure and Heart Rate in Acute Decompensated Heart Failure with Volume Overload


Duygu Kocyigit, Kadri Murat Gurses, Muhammed Ulvi Yalcin and Lale Tokgozoglu


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Ligand-modified Biopolymeric Nanoparticles as Efficient Tools for Targeted Cancer Therapy


Hasan Kouchakzadeh, Tooba Soudi, Niloofar Heshmati Aghda and Seyed Abbas Shojaosadati


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Modulation of Inflammatory Response to Implanted Biomaterials Using Natural Compounds


Maria Yanez, James Blanchette and Ehsan Jabbarzadeh


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Biomorphic Ceramics for Drug Delivery in Bone Tissue Regeneration


Patricia Diaz-Rodriguez and Mariana Landin


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Bioresponsive Injectable Hydrogels for On-demand Drug Release and Tissue Engineering


Arti Vashist, Ajeet Kaushik, Kayla Alexis, Rahul Dev Jayant, Vidya Sagar, Atul Vashist and Madhavan Nair


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Pharmacological Treatment of Bone Loss


Rui Pang and Weibo Xia


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‘Osteoimmunology’ Offers New Perspectives for the Treatment of Pathological Bone Loss


Hongrui Liu, Tingting Luo, Jiali Tan, Minqi Li and Jie Guo


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Nanotechnology: A Promising Tool Towards Wound Healing


Thaís Alberti, Daniela S. Coelho, Ana Voytena, Heloísa Pitz, Manuel de Prá, Letícia Mazzarino, Shirley Kuhnen, Rosa Maria Ribeiro-do-Valle, Marcelo Maraschin and Beatriz Veleirinho


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Methotrexate in the Treatment of Psoriasis and Rheumatoid Arthritis: Mechanistic Insights, Current Issues and Novel Delivery Approaches


P. Rajitha, Raja Biswas, M. Sabitha and R Jayakumar


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Gelatin as Biomaterial for Tissue Engineering


Mari Carmen Echave, Laura Saenz del Burgo, Jose Luis Pedraz and Gorka Orive


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Prospect of Combination and Sequential Therapies for Postmenopausal Osteoporosis


Hao Liu and Binbin Li


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Gender Medicine and Pharmacoeconomics: a Narrative Review of the International Literature of the Last 5 Years. A Revision of Evidences About the Relationship Between Gender and Economic Consumption in Health


Delia Colombo, Lucia Simoni and Emanuela Zagni


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Curcumin and Lung Cancer: the Role of microRNAs


Diana Lelli, Claudio Pedone, Muhammed Majeed and Amirhosssein Sahebkar


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Controlled Delivery of Bioactive Molecules for the Treatment of Chronic Wounds


J. Anjana, V. K. Rajan, R. Biswas and R. Jayakumar


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Role of Melatonin in Body Weight: A Systematic Review and Meta-Analysis


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