E-Pub Articles Ahead of Print ::: Current Pharmaceutical Design

ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 22, 46 Issues, 2016


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Current Pharmaceutical Design

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  • 73rd of 253 in Pharmacology & Pharmacy

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Editor-in-Chief:
William A. Banks
VAPSHCS/GRECC S-182
Building 1, Room 810A
1600 S. Columbian Way
Seattle, WA 98108
USA


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Current: 3.052
5 - Year: 3.132

E-Pub Articles Ahead of Print

Editorial: Perspectives and Challenges in Rational Exploitation of Phytochemicals in Cure, Control and Management of Diseases


Jayant Shankar Raut and Indu Pal Kaur.


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Selection of Antithrombotic Therapy in Patients with Atrial Fibrillation and Percutaneous Coronary Intervention


Theodoros A. Zografos and Demosthenes G Katritsis.


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The Microbial Quality Aspects and Decontamination Approaches for the Herbal Medicinal Plants and Products: An in-Depth Review


Daniela Dal Molim Ghisleni, Marina de Souza Braga, Irene Satiko Kikuchi, Mirela Braşoveanu, Monica R. Nemţanu, Kamal Dua and Terezinha de Jesus Andreoli Pinto.


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Antiplatelet Treatment in Stroke: New Insights


Haralampos Milionis, Angelos Liontos, Kostantinos Vemmos and Konstantinos Spengos.


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Polyketide Natural Products, Acetogenins from Graviola (Annona muricata L), its Biochemical, Cytotoxic Activity and Various Analyses Through Computational and Bio-Programming Methods


Keerthana Prabhakaran, Gnanam Ramasamy, Uma Doraisamy, Jayakanthan Mannu, K Rajamani and Jayadeepa Rajamani Murugesan.


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Common SAR Derived from Multiple QSAR Models on Vorinostat Derivatives Targeting HDACs in Tumor Treatment


Sugathan Praseetha, Srinivas Bandaru, Mukesh Yadav, Anuraj Nayarisseri and Sivanpillai Sureshkumar.


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Effects and Role of Multikinase Inhibitors in Thyroid Cancer.


Rasmus Laursen, Markus Wehland, Sascha Kopp, Jessica Pietsch, Manfred Infanger, Jirka Grosse and Daniela Grimm.


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Dry Eye Disease: Present Challenges in the Management and Future Trends


Zahraa Al-Saedi, Allison Zimmerman, Rinda Devi Bachu, Surajit Dey, Zahoor Shah, Reginald Baugh and Sai HS Boddu.


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Lipid Based Nanosystems for Curcumin: Past, Present and Future


Aditya P. Nayak, Tom Mills and Ian Norton.


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Antiplatelet Therapy in Acute Coronary Syndromes. Evidence Based Medicine


Evangelos Oikonomou, Georgia Vogiatzi, Georgios-Angelos Papamikroulis, Leon Naar, Gerasimos Siasos, Konstantinos Mourouzis, Theodoros Zografos, Manolis Vavuranakis, Alexis Antonopoulos and Dimitris Tousoulis.


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De novo design of new inhibitor of mutated tyrosine-kinase for the myeloid leukemia treatment


W. Pereira and I Camps.


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Identification of Small Molecule as a High Affinity β2 Agonist Irrespectively Targeting Wild and Mutated (Thr164Ile) β 2 Adrenergic Receptor in the Treatment of Bronchial Asthma


Srinivas Bandaru, Mallika Alvala, Jyothy Akka, Someshwar Rao Sagurthi, Anuraj Nayarisseri, Sanjeev Kumar Singh and Hema Prasad Mundluru.


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How the Protein Architecture of RNases III Influences their Substrate Specificity?


Guillermin Agüero-Chapin, Gisselle Pérez-Machado, Juan Collí Mull, Evys Ancede-Gallardo, Agostinho Antunes and Gustavo A de la Riva de la Riva.


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Probing the Hypothesis of SAR Continuity Restoration by the Removal of Activity Cliffs Generators in QSAR


Maykel Cruz-Monteagudo, José L. Medina-Franco, Yunier Perera-Sardiña, Fernanda Borges, Eduardo Tejera, Cesar Paz-y-Miño, Yunierkis Pérez-Castillo, Aminael Sánchez-Rodríguez, Zuleidys Contreras-Posada and M Natália D S Cordeiro.


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Metal Ions and Metal Complexes in Alzheimer’s Disease


Angelo Spinello, Riccardo Bonsignore, Giampaolo Barone, Bernhard K. Keppler and Alessio Terenzi.


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The Impact of Small Heat Shock Proteins (HspBs) in Alzheimer`s and Other Neurological Diseases


Nikola Golenhofen and Britta Bartelt-Kirbach.


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Non-Demented Individuals with Alzheimer’s Disease Neuropathology: Resistance to Cognitive Decline May Reveal New Treatment Strategies.


Olga Zolochevska and Giulio Taglialatela.


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Inflammation, Endothelial Dysfunction and Arterial Stiffness as Therapeutic Targets in Cardiovascular Medicine


Vittoriano Della Corte, Antonino Tuttolomondo, Rosaria Pecoraro and Antonio Pinto.


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Preventive and Therapeutic Role of Muscle Contraction Against Chronic Diseases


Domenico Di Raimondo, Gaia Musiari, Giuseppe Miceli, Valentina Arnao and Antonio Pinto.


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Pathogenetic Pathways of Cardiorenal Syndrome and Their Possible Therapeutic Implications


Kenichi Matsushita.


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Intestinal Barrier Dysfunction in Human Pathology and Aging


Marcel Cerqueira César Machado and Fabiano Pinheiro da Silva.


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A Case Report of IgG4-related Syndrome and Literature Review


Antonino Tuttolomondo, Irene Simonetta, Domenico Di Raimondo, Roberta Conigliaro, Francesca Corpora, Valerio Vassallo and Antonio Pinto.


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Discriminating Drug-like Compounds by Partition Trees with Quantum Similarity Indices and Graph Invariants.


Jesus V. de Julián-Ortiz, Rafael Gozalbes and Emili Besalú.


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Structure- and Ligand-Based Approaches to Evaluate Aporphynic Alkaloids from Annonaceae as Multi-Target Agent Against Leishmania donovani


Vitor Prates Lorenzo, Ana Silvia Suassuna Carneiro Lúcio, Luciana Scotti, Josean Fechine Tavares, José Maria Barbosa Filho, Tatjana Keesen de Souza Lima Clemente, Juliana da Câmara Rocha and Marcus Tullius Scotti.


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The Impact of Antiplatelet Treatment on Endothelial Function


Emmanuel Androulakis, Karl Norrington, Constantinos Bakogiannis, Eirini Lioudaki, Gerasimos Siasos and Dimitris Tousoulis.


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Repositioning the Old Fungicide Ciclopirox for New Medical Uses


Tao Shen and Shile Huang.


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The Interaction Between Gender and Diabetes Mellitus in the Coronary Heart Disease Risk


Evangelos Oikonomou, Vassiliki Tsigkou, George Lazaros, George-Angelo Papamikroulis, Spyridon Papaioannou, Gerasimos Siasos and Dimitris Tousoulis.


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Biomimetic approach to stimulate osteogenesis on titanium implant surfaces using fibronectin derived oligopeptide


Young-Dan Cho, Sung-Jun Kim, Han-Sol Bae, Won-Joon Yoon, Kyung-Hwa Kim, Hyun-Mo Ryoo, Yang-Jo Seol, Yong-Moo Lee, In-Chul Rhyu and Young Ku.


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Psychosocial Risk Factors Related to Ischemic Heart Disease in Women


Tina Varghese, Salim S. Hayek, Nikoloz Shekiladze, William M. Schultz and Nanette K Wenger.


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Oral Antiplatelet Treatment in STEMI: Current Practice and Future Considerations


Ioanna Xanthopoulou and Dimitrios Alexopoulos.


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Role of Colloidal Drug Delivery Carriers in Taxane-mediated Chemotherapy: A Review


Pramod Kumar, Kaisar Raza, Lokesh Kaushik, Ruchi Malik, Shweta Arora and Om Prakash Katare.


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Models for Self-Assembly of Nanoscale Systems with Biomedical Applications


Paula V. Messina, Ramon Rial and Juan M Ruso.


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Systems Medicine approaches to improving understanding, treatment, and clinical management of Neuroendocrine Prostate Cancer


Kamlesh K Yadav, Shameer Khader, Ben Readhead, Shalini S Yadav, Li Li, Andrew Kasarksis, Ashutosh K Tewari and Joel T Dudley.


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Computational Modeling and Experimental Facts of Mixed Self-Assembly Systems


Paula V. Messina, Jose Miguel Besada-Porto, Ramón Rial, Humberto González-Díaz and Juan M Ruso.


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Cell cycle kinases in osteosarcoma: potential for therapeutic intervention


Li Cheng, Chongchong Wang and Juehua Jing.


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Current status of ethosomes and elastic liposomes in dermal and transdermal drug delivery


Kevin Ita.


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Circulating microRNAs in hepatocellular carcinoma: potential diagnostic and prognostic biomarkers


Hamid Reza Mirzaei, Amirhossein Sahebkar, Foad Yazdi, Hosein Salehi, Mohammad Hasan Jafari, Afshin Namdar, Ehsan Khabazian, Mahmoud Reza Jaafri and Hamed Mirzaei.


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The potential use of piglets as human pediatric surrogate for preclinical pharmacokinetic and pharmacodynamic drug testing


Elke Gasthuys, Tim Vandecasteele, Pauline De Bruyne, Johan Vande Walle, Patrick De Backer, Pieter Cornillie, Mathias Devreese and Siska Croubels.


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ABC transporters in the development of multidrug resistance in cancer therapy


Angelika Długosz and Anna Janecka.


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Targeting inflammatory bowel diseases by nanocarriers loaded with small and biopharmaceutical anti-inflammatory drugs


Ana Beloqui, Régis Coco and Véronique Préat.


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Passive targeting of cyclophosphamide-loaded carbonate apatite nanoparticles to liver impedes breast tumor growth in a syngeneic model


S Tiash and EH Chowdhury.


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MicroRNA-208a Potentiates Angiotensin II-triggered Cardiac Myoblasts Apoptosis via Inhibiting Nemo-like kinase (NLK)


Ying Huang, Yang Yang, Yong He, Cheng Huang, Xiaoming Meng and Jun Li.


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Site-Specific Thiol-mediated PEGylation of Streptokinase Leads to Improved Properties with Clinical Potential


Pooja Sawhney, Shekhar Kumar, Neeraj Maheshwari, Sumeet Singh Guleria, Neelam Dhar, Radhika Kashyup and Girish Sahni.


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Aptamers to hemagglutinin: a novel tool for influenza virus recognition and neutralization


Elena Zavyalova and Alexey Kopylov.


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Αlpha-2 adrenergic and opioids receptors participation in mice gastroprotection of Abelmoschus esculentus lectin


Kátia A. Ribeiro, Hellíada V. Chaves, Samuel Mateus Pereira Filho, Isabela Ribeiro Pinto, Dina Andressa Martins Monteiro, Samuel Oliveira Matos, Tatiane Santi-Gadelha, Carlos Alberto de Almeida Gadelha, José Thalles Jocelino Gomes de Lacerda, Lissiana M. V. Aguiar, Karuza M. A. Pereira, Norma M. B. Benevides, Vicente de Paulo T. Pinto, Gerardo Cristino Filho, Mirna M. Bezerra and Antonio A R Silva.


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Type 2 Diabetes Mellitus and Alzheimer`s disease: Bridging the Pathophysiology and Management


Fahmida Alam, Md. Asiful Islam, Teguh Haryo Sasongko and Siew Hua Gan.


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Therapeutic Approaches Targeting Pathological Tau Aggregates


Julia Gerson and Rakez Kayed.


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Alzheimer’s Disease and Molecular Chaperones: Current Knowledge and the Future of Chaperonotherapy


Antonella Marino Gammazza, Celeste Caruso Bavisotto, Rosario Barone, Everly Conway de Macario and Alberto JL Macario.


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Statins in Stroke Prevention: Present and Future


Luis Castilla-Guerra, María del Carmen Fernandez-Moreno and Miguel Angel Colmenero- Camacho.


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Prognostic Significance of Asymptomatic Myocardial Ischemia in Women vs. Men


Ki E. Park and C Richard Conti.


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Bcl-2 Family Proteins Regulate Apoptosis and Epithelial to Mesenchymal Transition by Calcium Signals


Yanjiao Wu and Liling Tang.


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Evolution of Chemosensitivity and Resistance Assays as Predictors of Clinical Outcomes in Epithelial Ovarian Cancer Patients


Bradley J. Monk, Thomas J. Herzog and Krishnansu S Tewari.


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Gender and Cardiovascular Mortality in Northern and Ssouthern European Populations


Paolo Emilio Puddu, Michele Schiariti and Concetta Torromeo.


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Are Sex Differences in Outcomes of Patients with ACS from Observational Registries Similar to the Findings from Randomized Clinical Trials?


CP Gale and O Bebb.


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Hypertension and Ischemic Heart Disease in Women


Maria Dorobantu, Sebastian Onciul, Oana Florentina Tautu and Edina Cenko.


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From Mars to Venus: Gender Differences in the Management and Outcomes of Acute Coronary Syndromes


Nigel S. Tan and Andrew T Yan.


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Electrocardiographic and Cardiac Autonomic Indices - Implications of Sex-Specific Risk Stratification in Women After Acute Myocardial Infarction


Romy Ubrich, Petra Barthel, Anna Berkefeld, Katerina Hnatkova, Katharina M Huster, Michael Dommasch, Daniel Sinnecker, Alexander Steger, Georg Schmidt and Marek Malik.


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Atypical Chest Pain in ACS: A Trap Especially for Women


Beatrice Ricci, Edina Cenko, Elisa Varotti, Paolo Emilio Puddu and Olivia Manfrini.


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Risk Factors for Myocardial Infarction in Women and Men: A Review of the Current Literature


Lene Rørholm Pedersen, Daria Frestad, Marie Mide Michelsen, Naja Dam Mygind, Hanne Rasmusen, Hannah Elena Suhrs and Eva Prescott.


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Revascularization vs. Optimal Medical Therapy in Women with NSTE-ACS


Piera Capranzano, Claudia Tamburino and Corrado Tamburino.


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Barriers to Risk Stratification Accuracy in Ischemic Heart Disease in Women: The Role of Non-Obstructive Coronary Artery Disease


Edina Cenko and Raffaele Bugiardini.


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Atheroma Burden and Morphology in Women


Lina Badimon, María Borrell-Pagès and Teresa Padró.


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Macrocyclic Compounds: Emerging Opportunities for Current Drug Discovery


Lisha You, Rui An, Kun Liang, Bo Cui and Xinhong Wang.


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Editorial: Metabolic Disorders, Drug Development, Drug Design and Biomarkers


Gjumrakch Aliev, Ramon Cacabelos and V Prakash Reddy.


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Nanotechnology for Drug Delivery: Part III


Jian Zhong.


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Editorial: The Pathogenesis of Inflammation and Cancer in the Gastrointestinal Tract: From Basic Science to Translational Medicine


C.H. Cho and HY Wang.


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Editorial: Breaking the Skin Barrier: Achievements and the Future


Yasser Shahzad.


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Editorial: Mitochondrial Biogenesis: Pharmacological Approaches


Teresa Valero.


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Mechanisms of Inflammatory Response and Organ Dysfunction: Organ-Protective Strategy by Anesthetics


Noboru Hatakeyama and Naoyuki Matsuda.


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The Impact of Computational Structure-Based Methods on Drug Discovery


Charles H Reynolds.


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Editorial: The SNAP-tag Technology – A Versatile Tool with many Applications


Stefan Barth.


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Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement


Lothar Esser, Chang-An Yu and Di Xia.


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