E-Pub Articles Ahead of Print ::: Current Pharmaceutical Design

ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 22, 46 Issues, 2016


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Current Pharmaceutical Design

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  • 62nd of 254 in Pharmacology & Pharmacy

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William A. Banks
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E-Pub Articles Ahead of Print

Bivalirudin or Heparin Treatment During Transcatheter Valve Interventions: Where are we Now?


Ioannis Mastoris and George D Dangas.


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Atrial Fibrillation During or After TAVI: Incidence, Implications and Therapeutical Considerations


Manolis Vavuranakis, Angelos-Michail Kolokathis, Dimitrios A. Vrachatis, Konstantinos Kalogeras, Nikolaos A. Magkoutis, Sabi Fradi, Saïd Ghostine, Marianna Karamanou and Dimitrios Tousoulis.


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Editorial: Recent Trends in Nano-Biotechnology Reinforcing Contemporary Pharmaceutical Design


Ajay Vikram Singh.


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Recent Advances in Neuroinflammation Therapeutics: PPARs/LXR as Neuroinflammatory Modulators.


Sussy Bastías-Candia, A. Nicolás Garrido, Juan M. Zolezzi and Nibaldo C Inestrosa.


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Historical Hallmarks of Anticoagulation and Antiplatelet Agents


Gregory Tsoucalas, Jacques Chevallier, Marianna Karamanou, Theodoros Papaioannou, Markos Sgantzos and George Androutsos.


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Cognition and Emotions in Recurrent Depressive Disorders - The Role of Inflammation and the Kynurenine Pathway


Monika Talarowska and Piotr Gałecki.


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Depression, Serotonin and Tryptophan


Liliana Dell'Osso, Claudia Carmassi, Federico Mucci and Donatella Marazziti.


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Tryptophan Catabolites and Migraine


Zsuzsanna Bohár, Árpád Párdutz and László Vécsei.


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Strategies to Avoid TAVI-related Acute Kidney Injury


Polydoros N. Kampaktsis, Dmitriy N. Feldman and Konstantinos Charitakis.


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Balancing the Risks of Thrombosis and Bleeding Following Transcatheter Aortic Valve Implantation: Current State-of-Evidence


Rishi Puri, Omar Abdul-Jawad Altisent, Francisco Campelo-Parada, Maria del Trigo, Ander Regueiro and Josep Rodés-Cabau.


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The Pictet-Spengler Reaction Still On Stage


Cinzia Ingallina, Ilaria D'Acquarica, Giuliano Delle Monache, Francesca Ghirga, Deborah Quaglio, Patrizio Ghirga, Simone Berardozzi, Violeta Markovic and Bruno Botta.


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Mechanisms of Improvement of Left Ventricular Function by Intracoronary Human Umbilical Cord-Derived Mesenchymal Stem Cell Infusion in Very Old Patients with Coronary Chronic Total Occlusion


Xia Li, You-dong Hu, Ying Chen, Hua-lan Zhou, Feng-lin Zhang, Dian-xuan Guo and Qing-na Zhao.


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Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier


David S. Hersh, Aniket S. Wadajkar, Nathan B. Roberts, Jimena G. Perez, Nina P. Connolly, Victor Frenkel, Jeffrey A. Winkles, Graeme F. Woodworth and Anthony J Kim.


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Melatonin and Synthetic Melatoninergic Agonists in Psychiatric and Age-associated Disorders: Successful and Unsuccessful Approaches


Rüdiger Hardeland.


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General or Local Anesthesia for TAVI? A Systematic Review of the Literature and Meta-Analysis


E.H.A Maas, B.M.A. Pieters, M. Van de Velde and S Rex.


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Ocular Drug Delivery - New Strategies for Targeting Anterior and Posterior Segments of the Eye


Joana F. Fangueiro, Francisco Veiga, Amélia M. Silva and Eliana B Souto.


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Algorithms and Criteria for Transcatheter Aortic Valve Replacement Patient Selection: Current Status and Future Trends


Scott M Lilly and William T Abraham.


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Editorial: Drug Delivery: Open Sesame Strategies for the One Thousand and One Body Barriers


Silvia Muro.


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Editorial: Neuroinflammation a Common Link in Neurodegenerative Neurological and Psychiatric Disorders


Valentina Echeverría.


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Editorial: Metabolic Disorders, Drug Development, Drug Design and Biomarkers


Gjumrakch Aliev, Ramon Cacabelos and V Prakash Reddy.


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Coagulation Factor XIIIA (F13A1): novel perspectives in treatment and pharmacogenetics.


Gemmati Donato, Vigliano Marco, Burini Francesco, Mari Rosella, Hodeib Hossam Abd El Mohsein, Parmeggiani Francesco and Serino M Luisa.


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Antiplatelet Agents in Cardiology: A Report on Aspirin, Clopidogrel, Prasugrel, and Ticagrelor


Paul P. Dobesh, Sara Varnado and Meagan Doyle.


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Pharmacogenomics of Oral Antithrombotic Drugs


Flavia Storelli, Youssef Daali, Jules Desmeules, Jean-Luc Reny and Pierre Fontana.


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Nanotechnology for Drug Delivery: Part III


Jian Zhong.


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Editorial: The Pathogenesis of Inflammation and Cancer in the Gastrointestinal Tract: From Basic Science to Translational Medicine


C.H. Cho and HY Wang.


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Editorial: Breaking the Skin Barrier: Achievements and the Future


Yasser Shahzad.


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Evaluation of the In Vivo Safety Profiles of Rictor Inhibition Using a Zebrafish Model


Yang Cao, Lijun Jiang, Lei Zhao, Xiaoxi Zhou, Na Wang, Peilin Zhang, Yuting Tang and Jianfeng Zhou.


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The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs


Feng Wang, Junsheng Lin and Ruian Xu.


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Editorial: Mitochondrial Biogenesis: Pharmacological Approaches


Teresa Valero.


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Mechanisms of Inflammatory Response and Organ Dysfunction: Organ-Protective Strategy by Anesthetics


Noboru Hatakeyama and Naoyuki Matsuda.


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VEGF and Colon Cancer Growth Beyond Angiogenesis: Does VEGF Directly Mediate Colon Cancer Growth Via a Non-angiogenic Mechanism?


Amrita Ahluwalia, Michael K. Jones, Tamara Matysiak-Budnik and Andrzej S Tarnawski.


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The Impact of Computational Structure-Based Methods on Drug Discovery


Charles H Reynolds.


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Anti-miRNA-23a Oligonucleotide Suppresses Glioma Cells Growth by Targeting Apoptotic Protease Activating Factor-1


Shizhong Lian, Ruyi Shi, Tao Bai, Yang Liu, Wang Miao, Hongqin Wang, Xiaodong Liu and Yimin Fan.


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Editorial: The SNAP-tag Technology – A Versatile Tool with many Applications


Stefan Barth.


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Differential Influences of Gastric Bypass and Sleeve Gastrectomy on Plasma Nesfatin-1 and Obestatin Levels in Patients with Type 2 Diabetes Mellitus


Wei-Jei Lee, Chih-Yen Chen, Kong-Han Ser, Keong Chong, Shu-Chun Chen, Pui-Ching Lee, You-Di Liao and Shou-Dong Lee.


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Probiotics for the Prevention and Treatment of Allergies, with an Emphasis on Mode of Delivery and Mechanism of Action


Satya Prakash, Catherine Tomaro-Duchesneau, Shyamali Saha, Laetitia Rodes, Imen Kahouli and Meenakshi Malhotra.


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Consumption of Mixed Fruit-juice Drink and Vitamin C Reduces Postprandial Stress Induced by a High Fat Meal in Healthy Overweight Subjects


Ilaria Peluso, Debora V. Villano, Susan A. Roberts, Eleonora Cesqui, Anna Raguzzini, Gina Borges, Alan Crozier, Giovina Catasta, Elisabetta Toti and Mauro Serafini.


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Immunomodulating and Anti-allergic Effects of Negroamaro and Koshu Vitis vinifera Fermented Grape Marc (FGM)


Giuseppe Marzulli, Thea Magrone, Luisa Vonghia, Masahiro Kaneko, Hiroaki Takimoto, Yoshio Kumazawa and Emilio Jirillo.


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Potential Use of Dietary Natural Products, Especially Polyphenols, for Improving Type-1 Allergic Symptoms


Kumazawa Y, Takimoto H, Matsumoto T and Kawaguchi K.


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Omega-6 and Omega-3 Polyunsaturated Fatty Acids and Allergic Diseases in Infancy and Childhood


Elizabeth A. Miles and Philip C Calder.


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Factors Affecting Residual Platelet Aggregation in Prasugrel Treated Patients


Dimitrios Alexopoulos, Ioanna Xanthopoulou, Angelos Perperis, Argyro Siapika, Katerina Stavrou, Evropi Tsoni, Periklis Davlouros and George Hahalis.


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What Fans the Fire: Insights into Mechanisms of Leptin in Metabolic Syndrome- Associated Heart Diseases


Maolong Dong and Jun Ren.


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Transactivation of ErbB Receptors by Leptin in the Cardiovascular System: Mechanisms, Consequences and Target for Therapy


Jerzy Bełtowski and Anna Jazmroz-Wiśniewska.


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Structural Insights into Chitinolytic Enzymes and Inhibition Mechanisms of Selective Inhibitors


Tian Liu, Lei Chen, Qiang Ma, Xu Shen and Qing Yang.


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Structure-based Design of Conformationally Flexible Reverse Transcriptase Inhibitors to Combat Resistant HIV


Ge-Fei Hao, Sheng-Gang Yang and Guang-Fu Yang.


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Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement


Lothar Esser, Chang-An Yu and Di Xia.


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ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development


Young Hee Choi, Ai-Ming Yu and Ai-Ming Yu.


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Structure-Based Drug Design to Overcome Drug Resistance: Challenges and Opportunities


Rafaela S. Ferreira1, Adriano D. Andricopulo and Adriano D Andricopulo.


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Novel Next-Generation Sequencing and Networks-Based Therapeutic Targets: Realistic and More Effective Drug Design and Discovery


Dimitrios H. Roukos, Giannis G. Baltogiannis, Christos S. Katsouras, Aris Bechlioulis, Katerina K. Naka, Charalambos Batsis, Theodore Liakakos and Lampros K Michalis.


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Endothelial Dysfunction and the Effects of TNF Inhibitors on the Endothelium in Psoriasis and Psoriatic Arthritis: A Systematic Review


Elizabeth A. Brezinski, Matthew R. Follansbee, Ehrin J. Armstrong and April W Armstrong.


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Effects of Biologic Agents and Other Disease-Modifying Antirheumatic Drugs on Cardiovascular Outcomes in Psoriasis and Psoriatic Arthritis: A Systematic Review


April W. Armstrong, Elizabeth A. Brezinski, Matthew R. Follansbee and Ehrin J Armstrong.


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Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents


Yan Lin, Zhi-Yi Chen and Feng Yang.


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Long-term Etanercept Therapy Favors Weight Gain and Ameliorates Cachexia in Rheumatoid Arthritis Patients: Roles of Gut Hormones and Leptin


Chih-Yen Chen, Chang-Youh Tsai, Pui-Ching Lee and Shou-Dong Lee.


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The Effect of First-in-Class Small Molecule RhoA Inhibitor, HL07, on the Phenylephrine-induced Artery Contraction


Yan Zhang, Jing Deng, Sheng Ma, Lin Xue, Jin Zhu, Wei-liang Zhu, Hua-liang Jiang, Jian Li and Li-yan Miao.


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Non-Systemic Drugs: A Critical Review


Dominique Charmot.


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Advancement of Targeted Ultrasound Contrast Agents and their Applications in Molecular Imaging and Targeted Therapy


Feng Yang, Zhi-Yi Chen and Yan Lin.


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Atorvastatin Sensitises Vascular Smooth Muscle Cells, but not Endothelial Cells, to TNF-α-induced Cell Death


Arturo Giordano, Simona Romano, Giovanna Nappo, Stefano Messina, Michele Polimeno, Nicola Corcione, Gaetano Calì, Paolo Ferraro, Mario Monaco, Nicola Zambrano and Maria Fiammetta Romano.


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Carotenoids and Cardiovascular Risk


Paola Giordano, Pietro Scicchitano, Manuela Locorotondo, Cosimo Mandurino, Gabriella Ricci, Santa Carbonara, Michele Gesualdo, Annapaola Zito, Annamaria Dachille, Paola Caputo, Roberta Riccardi, Giulia Frasso, Giuseppe Lassandro, Antonio Di Mauro and Marco Matteo Ciccone.


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A Computational Study of the Oligosaccharide Binding Sites in the Lectin-Like Domain of Tumor Necrosis Factor and the TNF-derived TIP Peptide


Alexander Dulebo, Rüdiger Ettrich, Rudolf Lucas and David Kaftan.


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Target-based Anti-angiogenic Therapy in Breast Cancer


Markus Wehland, Johann Bauer, Manfred Infanger and Daniela Grimm.


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Preclinical Safety and Pharmacokinetic Profile of 3K3A-APC, a Novel, Modified Activated Protein C for Ischemic Stroke


Patricia D. Williams, Berislav V. Zlokovic, John H. Griffin, Kent E. Pryor and Thomas P Davis.


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