E-Pub Articles Ahead of Print ::: Current Pharmaceutical Design

ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)

Volume 21, 42 Issues, 2015

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Current Pharmaceutical Design

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E-Pub Articles Ahead of Print

Anti-Cancer Cytotoxic Effects of Multiwalled Carbon Nanotubes
Lorena García-Hevia, Rafael Valiente, Jesús González, Héctor Terán, José Luís Fernández-Luna, Juan C. Villegas and Mónica L. Fanarraga
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Nanofibers Based Antibacterial Drug Design, Delivery and Applications
Kezban Ulubayram, Semih Calamak, Reza Shahbazi and Ipek Eroglu
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Smart Electrospun Nanofibers for Controlled Drug Release: Recent Advances and New Perspectives
Lin Weng and Jingwei Xie
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Drug-Incorporated Electrospun Fibers Efficiently Prevent Postoperative Adhesion
Bo Shi, Jianxun Ding, Junchao Wei, Changfeng Fu, Xiuli Zhuang and Xuesi Chen
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Immobilization and Application of Electrospun Nanofiber Scaffold-based Growth Factor in Bone Tissue Engineering
Guobao Chen and Yonggang Lv
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Scaffold-based Drug Delivery for Cartilage Tissue Regeneration
K. T. Shalumon and Jyh-Ping Chen
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Controlled Bioactive Molecules Delivery Strategies for Tendon and Ligament Tissue Engineering using Polymeric Nanofibers
Thomas Kok Hiong TEH, James Cho Hong GOH and Siew Lok TOH
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Nanofibers based Tissue Engineering and Drug Delivery Approaches for Myocardial Regeneration
Jyotsna Joshi and Chandrasekhar R. Kothapalli
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Implication of Nanofibers in Oral Drug Delivery
Himani Kapahi, Nikhat Mansoor Khan, Ankur Bhardwaj and Neeraj Mishra
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Recent Advancements in Carbon Nanofiber and Carbon Nanotube Applications in Drug Delivery and Tissue Engineering
David A. Stout
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Studies on Drug – Human Serum Albumin Binding: The Current State of the Matter
Zvetanka D. Zhivkova
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Structure and Enzymatic Activities of Human Serum Albumin
Y u Wang, Shihua Wang and Mingdong Huang
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Drugs Modulate Allosterically Heme-Fe-Recognition by Human Serum Albumin and Heme-Fe-Mediated Reactivity
Alessandra di Masi, Loris Leboffe, Viviana Trezza, Gabriella Fanali, Massimo Coletta, Mauro Fasano and Paolo Ascenzi
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Evaluation of Interactions Between Platinum-/Ruthenium-Based Anticancer Agents and Human Serum Albumin: Development of HSA Carrier for Metal-Based Drugs
Y i Gou, Yao Zhang, Feng Yang and Hong Liang
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Review: Modifications of Human Serum Albumin and Their Binding Effect
Philbert Lee and Xiaoyang Wu
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Recent Advances on the Development of Pharmacotherapeutic Agents on the Basis of Human Serum Albumin
Fang Liu, Jing Mu and Bengang Xing
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Molecular Imaging and Targeted Drug Delivery using Albumin-Based Nanoparticles
J Young Yhee, Jangwook Lee, Hyeyoun Chang, Lee Jeewon, Ick Chan Kwon and Kwangmeyung Kim
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Recombinant Human Serum Albumin Fusion Proteins and Novel Applications in Drug Delivery and Therapy
Brian Rogers, Daoyuan Dong, Zhijun Li and Zhiyu Li
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The Advancement of Human Serum Albumin-Based Molecular Probes for Molecular Imaging
Wei Cao, Xiaoting Lu and Zhen Cheng
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Anti-VEGF Drugs in Eye Diseases: Local Therapy with Potential Systemic Effects
Markus van der Giet, Cornelia Henkel, Mirjam Schuchardt and Markus Tölle
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The Potential Effect of Fluorinated Compounds in the Treatment of Alzheimer’s Disease
Bárbara Gomes, Joana A. Loureiro, Manuel A.N. Coelho and Maria do Carmo Pereira
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Anticancer Advances of Matrine and Its Derivatives
Jianping Yong, Xiaoyuan Wu and Canzhong Lu
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Skeletal Muscle Cell Behavior After Physical Agent Treatments
Michela Battistelli, Sara Salucci, Michele Guescini, Davide Curzi, Vilberto Stocchi and Elisabetta Falcieri
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Nanofiber-based Drug Design, Delivery and Application
Yonggang Lv
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Analysis of Edg-Like LPA Receptor-Ligand Interactions
Balazs Balogh, Tamas Pazmany and Peter Matyus
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Multiple Roles of Fibroblast Growth Factor 21 in Metabolism
Li Li and Liling Tang
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Evaluation of the In Vivo Safety Profiles of Rictor Inhibition Using a Zebrafish Model
Yang Cao, Lijun Jiang, Lei Zhao, Xiaoxi Zhou, Na Wang, Peilin Zhang, Yuting Tang and Jianfeng Zhou
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Therapeutic Effect of Ghrelin in the Course of Ischemia/Reperfusion-induced Acute Pancreatitis
J Bukowczan, Z Warzecha, P Ceranowicz, B Kusnierz-Cabala, R Tomaszewska and A Dembinski
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Application of Molecular Imaging Technologies in Antitumor Drug Development and Therapy
Yan Lin, Zhi-Yi Chen, Feng Yang, Jin-Shan Zhang, Yi-Xiang Wang, Jin-Bing Liu, Jian-Yi Liao, Yang-Ying Liao, Qiu-Lan Zhou, Bing-Cheng Li and Hui-Ying Liang
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Sarcosine-Based Glycine Transporter Type-1 (GlyT-1) Inhibitors Containing Pyridazine Moiety: A Further Search for Drugs with Potential to Influence Schizophrenia Negative Symptoms
Laszlo G. Harsing, Julia Timar, Geza Szabo, Szabolcs Udvari, Katalin M. Nagy, Bernadett Marko, Gabriella Zsilla, Andrea Czompa, Pal Tapolcsanyi, Akos Kocsis and Peter Matyus
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Applications of Important Polysaccharides in Drug Delivery
Gangliang Huang, Xinya Mei, Feng Xiao, Xin Chen, Qilin Tang and Daquan Peng
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CXCR4 and CXCL12 Expression in Rectal Tumors of Stage IV Patients Before and After Local Radiotherapy and Systemic Neoadjuvant Treatment
Karin Tamas, Urszula M. Domanska, Tonnis H. van Dijk, Hetty Timmer-Bosscha, Klaas Havenga, Arend Karrenbeld, Wim J. Sluiter, Jannet C. Beukema, Marcel A.T.M. van Vugt, Elisabeth G.E. de Vries, Geke A.P. Hospers and Annemiek M.E. Walenkamp
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Phenylbutyric Acid: Simple Structure – Multiple Effects
Magdalena Kusaczuk, Marek Bartoszewicz and Marzanna Cechowska-Pasko
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25OH-Vitamin D3 Levels in Obesity and Metabolic Syndrome—Unaltered in Young and not Correlated to Carotid IMT in all Ages
Harald Mangge, Sieglinde Zelzer, Andreas Meinitzer, Ingeborg Stelzer, Wolfgang J Schnedl, Daniel Weghuber, Dietmar Fuchs, Teodor T Postolache, Elmar Aigner, Christian Datz and Eva Z Reininghaus
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Novel kynurenic Acid Analogues in the Treatment of Migraine and Neurodegenerative Disorders: Preclinical Studies and Pharmaceutical Design
János Tajti, Zsófia Majláth, Délia Szok, Anett Csáti, József Toldi, Ferenc Fülöp and László Vécsei
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Microrna-21: A Central Regulator of Fibrotic Diseases Via Various Targets
Ying Huang, Yong He and Jun Li
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Treatment of Leishmaniasis: A Review and Assessment of Recent Research
Ehab Kotb Elmahallawy and Ahmad Agil
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The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs
Feng Wang, Junsheng Lin and Ruian Xu
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Editorial: Mitochondrial Biogenesis: Pharmacological Approaches
Teresa Valero
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Mechanisms of Inflammatory Response and Organ Dysfunction: Organ-Protective Strategy by Anesthetics
Noboru Hatakeyama and Naoyuki Matsuda
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VEGF and Colon Cancer Growth Beyond Angiogenesis: Does VEGF Directly Mediate Colon Cancer Growth Via a Non-angiogenic Mechanism?
Amrita Ahluwalia, Michael K. Jones, Tamara Matysiak-Budnik and Andrzej S. Tarnawski
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The Impact of Computational Structure-Based Methods on Drug Discovery
Charles H. Reynolds
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Human Use of Leucoselect® Phytosome® with Special Reference to Inflammatoryallergic Pathologies in Frail Elderly Patients
Thea Magrone, Vittorio Pugliese, Sergio Fontana and Emilio Jirillo
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Anti-miRNA-23a Oligonucleotide Suppresses Glioma Cells Growth by Targeting Apoptotic Protease Activating Factor-1
Shizhong Lian, Ruyi Shi, Tao Bai, Yang Liu, Wang Miao, Hongqin Wang, Xiaodong Liu and Yimin Fan
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Editorial: The SNAP-tag Technology – A Versatile Tool with many Applications
Stefan Barth
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Gender Based Differences in Stress-induced Gastric Ulcer Formation and its Regulation by Nitric Oxide (NO): An Experimental Study
Kavita Gulati, Ayanabha Chakraborti and Arunabha Ray
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Differential Influences of Gastric Bypass and Sleeve Gastrectomy on Plasma Nesfatin-1 and Obestatin Levels in Patients with Type 2 Diabetes Mellitus
Wei-Jei Lee, Chih-Yen Chen, Kong-Han Ser, Keong Chong, Shu-Chun Chen, Pui-Ching Lee, You-Di Liao and Shou-Dong Lee
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Probiotics for the Prevention and Treatment of Allergies, with an Emphasis on Mode of Delivery and Mechanism of Action
Satya Prakash, Catherine Tomaro-Duchesneau, Shyamali Saha, Laetitia Rodes, Imen Kahouli and Meenakshi Malhotra
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Consumption of Mixed Fruit-juice Drink and Vitamin C Reduces Postprandial Stress Induced by a High Fat Meal in Healthy Overweight Subjects
Ilaria Peluso, Debora V. Villano, Susan A. Roberts, Eleonora Cesqui, Anna Raguzzini, Gina Borges, Alan Crozier, Giovina Catasta, Elisabetta Toti and Mauro Serafini
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Immunomodulating and Anti-allergic Effects of Negroamaro and Koshu Vitis vinifera Fermented Grape Marc (FGM)
Giuseppe Marzulli, Thea Magrone, Luisa Vonghia, Masahiro Kaneko, Hiroaki Takimoto, Yoshio Kumazawa and Emilio Jirillo
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Potential Use of Dietary Natural Products, Especially Polyphenols, for Improving Type-1 Allergic Symptoms
Kumazawa Y, Takimoto H, Matsumoto T and Kawaguchi K
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Omega-6 and Omega-3 Polyunsaturated Fatty Acids and Allergic Diseases in Infancy and Childhood
Elizabeth A. Miles and Philip C. Calder
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Factors Affecting Residual Platelet Aggregation in Prasugrel Treated Patients
Dimitrios Alexopoulos, Ioanna Xanthopoulou, Angelos Perperis, Argyro Siapika, Katerina Stavrou, Evropi Tsoni, Periklis Davlouros and George Hahalis
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What Fans the Fire: Insights into Mechanisms of Leptin in Metabolic Syndrome- Associated Heart Diseases
Maolong Dong and Jun Ren
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Transactivation of ErbB Receptors by Leptin in the Cardiovascular System: Mechanisms, Consequences and Target for Therapy
Jerzy Bełtowski and Anna Jazmroz-Wiśniewska
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Structural Insights into Chitinolytic Enzymes and Inhibition Mechanisms of Selective Inhibitors
Tian Liu, Lei Chen, Qiang Ma, Xu Shen and Qing Yang
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Structure-based Design of Conformationally Flexible Reverse Transcriptase Inhibitors to Combat Resistant HIV
Ge-Fei Hao, Sheng-Gang Yang and Guang-Fu Yang
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Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement
Lothar Esser, Chang-An Yu and Di Xia
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ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development
Young Hee Choi, Ai-Ming Yu and Ai-Ming Yu
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Structure-Based Drug Design to Overcome Drug Resistance: Challenges and Opportunities
Rafaela S. Ferreira1, Adriano D. Andricopulo and Adriano D. Andricopulo
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Novel Next-Generation Sequencing and Networks-Based Therapeutic Targets: Realistic and More Effective Drug Design and Discovery
Dimitrios H. Roukos, Giannis G. Baltogiannis, Christos S. Katsouras, Aris Bechlioulis, Katerina K. Naka, Charalambos Batsis, Theodore Liakakos and Lampros K. Michalis
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Endothelial Dysfunction and the Effects of TNF Inhibitors on the Endothelium in Psoriasis and Psoriatic Arthritis: A Systematic Review
Elizabeth A. Brezinski, Matthew R. Follansbee, Ehrin J. Armstrong and April W. Armstrong
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Effects of Biologic Agents and Other Disease-Modifying Antirheumatic Drugs on Cardiovascular Outcomes in Psoriasis and Psoriatic Arthritis: A Systematic Review
April W. Armstrong, Elizabeth A. Brezinski, Matthew R. Follansbee and Ehrin J. Armstrong
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Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents
Yan Lin, Zhi-Yi Chen and Feng Yang
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Long-term Etanercept Therapy Favors Weight Gain and Ameliorates Cachexia in Rheumatoid Arthritis Patients: Roles of Gut Hormones and Leptin
Chih-Yen Chen, Chang-Youh Tsai, Pui-Ching Lee and Shou-Dong Lee
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The Effect of First-in-Class Small Molecule RhoA Inhibitor, HL07, on the Phenylephrine-induced Artery Contraction
Yan Zhang, Jing Deng, Sheng Ma, Lin Xue, Jin Zhu, Wei-liang Zhu, Hua-liang Jiang, Jian Li and Li-yan Miao
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Non-Systemic Drugs: A Critical Review
Dominique Charmot
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Advancement of Targeted Ultrasound Contrast Agents and their Applications in Molecular Imaging and Targeted Therapy
Feng Yang, Zhi-Yi Chen and Yan Lin
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Atorvastatin Sensitises Vascular Smooth Muscle Cells, but not Endothelial Cells, to TNF-α-induced Cell Death
Arturo Giordano, Simona Romano, Giovanna Nappo, Stefano Messina, Michele Polimeno, Nicola Corcione, Gaetano Calì, Paolo Ferraro, Mario Monaco, Nicola Zambrano and Maria Fiammetta Romano
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Carotenoids and Cardiovascular Risk
Paola Giordano, Pietro Scicchitano, Manuela Locorotondo, Cosimo Mandurino, Gabriella Ricci, Santa Carbonara, Michele Gesualdo, Annapaola Zito, Annamaria Dachille, Paola Caputo, Roberta Riccardi, Giulia Frasso, Giuseppe Lassandro, Antonio Di Mauro and Marco Matteo Ciccone
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A Computational Study of the Oligosaccharide Binding Sites in the Lectin-Like Domain of Tumor Necrosis Factor and the TNF-derived TIP Peptide
Alexander Dulebo, Rüdiger Ettrich, Rudolf Lucas and David Kaftan
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Target-based Anti-angiogenic Therapy in Breast Cancer
Markus Wehland, Johann Bauer, Manfred Infanger and Daniela Grimm
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Preclinical Safety and Pharmacokinetic Profile of 3K3A-APC, a Novel, Modified Activated Protein C for Ischemic Stroke
Patricia D. Williams, Berislav V. Zlokovic, John H. Griffin, Kent E. Pryor and Thomas P. Davis
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