E-Pub Articles Ahead of Print ::: Current Pharmaceutical Design

ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 22, 46 Issues, 2016


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Current Pharmaceutical Design

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  • 62nd of 254 in Pharmacology & Pharmacy

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Editor-in-Chief:
William A. Banks
VAPSHCS/GRECC S-182
Building 1, Room 810A
1600 S. Columbian Way
Seattle, WA 98108
USA


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Current: 3.452
5 - Year: 3.504

E-Pub Articles Ahead of Print

Editorial: Myokines and Exercise Training: More Shadows than Lights


Domenico Di Raimondo.


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Nano-Precipitation: Preparation and Application in the Field of Pharmacy


Thao Truong-DinhTran, Phuong Ha-Lien Tran, Khanh Tu Nguyen and Van-Thanh Tran.


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Nanoparticles Based on Plasma Proteins for Drug Delivery Applications


Ayşen Tezcaner, Erkan Türker Baran and Dilek Keskin.


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Polymer Particulates in Drug Delivery


Harmeet Kaur, Virender Kumar, Krishan Kumar, Sandeep Rathor, Parveen Kumari and Jasbir Singh.


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Role of Osmolytes in Regulating Immune System


Tarun Kumar, Manisha Yadav and Laishram Rajendrakumar Singh.


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Macrocyclic Compounds: Emerging Opportunities for Current Drug Discovery


Lisha You, Rui An, Kun Liang, Bo Cui and Xinhong Wang.


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Current Understanding of HSP90 as a Novel Therapeutic Target: An Emerging Approach for the Treatment of Cancer


Absarul Haque, Qamre Alam, Mohammad Zubair Alam, Esam I. Azhar, Khalid Hussain Wali Sait, Nisreen Anfina, Gohar Mushtaq, Mohammad Amjad Kamal and Mahmood Rasool.


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Drug Delivery to CNS: Challenges and Opportunities with Emphasis on Biomaterials Based Drug Delivery Strategies


Ekta Khambhla, Viral Shah and Kalpesh Baviskar.


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Immunology of Chronic Obstructive Pulmonary Disease and Sulfur Mustard- Induced Airway Injuries: Implications for Immunotherapeutic Interventions


Yunes Panahi, Mostafa Ghanei, Nazila Nikravanfard, Farzaneh Nikravesh, Claudio Pedone and Amirhossein Sahebkar.


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Editorial: Managing Strategies for Diverse Diseases: Challenges from Bench to Bedside Translation in Successful Drug Discovery and Development (Part B)


Mohammad A. Kamal and Nigel H Greig.


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Editorial: Polypharmacology in Drug Discovery


Luciana Scotti and Marcus T Scotti.


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Epidermal Growth Factor Receptor (EGFR) and its Cross-talks with Topoisomerases: Challenges and Opportunities for Multi-Target Anticancer Drugs


Monika Chauhan, Gourav Sharma, Gaurav Joshi and Raj Kumar.


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Natural Polymeric Nanoparticles for Brain-Targeting: Implications on Drug and Gene Delivery


Ahmed O. Elzoghby, Mahmoud M. Abd-Elwakil, Kholod Abd-Elsalam, Mustafa T. Elsayed, Yosra Hashem and Ola Mohamed.


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Lipoprotein Like Nanoparticles Used in Drug and Gene Delivery


Jaleh Varshosaz, Hamed Vakilzadeh and Erfaneh Ghassami.


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The Prominent Role of Protein-Based Delivery Systems on the Development of Cancer Treatment


Hasan Kouchakzadeh, Seyed and Abbas Shojaosadati.


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Mechanisms of Improvement of Left Ventricular Function by Intracoronary Human Umbilical Cord-Derived Mesenchymal Stem Cell Infusion in Very Old Patients with Coronary Chronic Total Occlusion


Xia Li, You-dong Hu, Ying Chen, Hua-lan Zhou, Feng-lin Zhang, Dian-xuan Guo and Qing-na Zhao.


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Editorial: Metabolic Disorders, Drug Development, Drug Design and Biomarkers


Gjumrakch Aliev, Ramon Cacabelos and V Prakash Reddy.


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Nanotechnology for Drug Delivery: Part III


Jian Zhong.


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Editorial: The Pathogenesis of Inflammation and Cancer in the Gastrointestinal Tract: From Basic Science to Translational Medicine


C.H. Cho and HY Wang.


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Editorial: Breaking the Skin Barrier: Achievements and the Future


Yasser Shahzad.


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Evaluation of the In Vivo Safety Profiles of Rictor Inhibition Using a Zebrafish Model


Yang Cao, Lijun Jiang, Lei Zhao, Xiaoxi Zhou, Na Wang, Peilin Zhang, Yuting Tang and Jianfeng Zhou.


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The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs


Feng Wang, Junsheng Lin and Ruian Xu.


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Editorial: Mitochondrial Biogenesis: Pharmacological Approaches


Teresa Valero.


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Mechanisms of Inflammatory Response and Organ Dysfunction: Organ-Protective Strategy by Anesthetics


Noboru Hatakeyama and Naoyuki Matsuda.


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VEGF and Colon Cancer Growth Beyond Angiogenesis: Does VEGF Directly Mediate Colon Cancer Growth Via a Non-angiogenic Mechanism?


Amrita Ahluwalia, Michael K. Jones, Tamara Matysiak-Budnik and Andrzej S Tarnawski.


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The Impact of Computational Structure-Based Methods on Drug Discovery


Charles H Reynolds.


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Anti-miRNA-23a Oligonucleotide Suppresses Glioma Cells Growth by Targeting Apoptotic Protease Activating Factor-1


Shizhong Lian, Ruyi Shi, Tao Bai, Yang Liu, Wang Miao, Hongqin Wang, Xiaodong Liu and Yimin Fan.


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Editorial: The SNAP-tag Technology – A Versatile Tool with many Applications


Stefan Barth.


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Differential Influences of Gastric Bypass and Sleeve Gastrectomy on Plasma Nesfatin-1 and Obestatin Levels in Patients with Type 2 Diabetes Mellitus


Wei-Jei Lee, Chih-Yen Chen, Kong-Han Ser, Keong Chong, Shu-Chun Chen, Pui-Ching Lee, You-Di Liao and Shou-Dong Lee.


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Probiotics for the Prevention and Treatment of Allergies, with an Emphasis on Mode of Delivery and Mechanism of Action


Satya Prakash, Catherine Tomaro-Duchesneau, Shyamali Saha, Laetitia Rodes, Imen Kahouli and Meenakshi Malhotra.


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Consumption of Mixed Fruit-juice Drink and Vitamin C Reduces Postprandial Stress Induced by a High Fat Meal in Healthy Overweight Subjects


Ilaria Peluso, Debora V. Villano, Susan A. Roberts, Eleonora Cesqui, Anna Raguzzini, Gina Borges, Alan Crozier, Giovina Catasta, Elisabetta Toti and Mauro Serafini.


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Immunomodulating and Anti-allergic Effects of Negroamaro and Koshu Vitis vinifera Fermented Grape Marc (FGM)


Giuseppe Marzulli, Thea Magrone, Luisa Vonghia, Masahiro Kaneko, Hiroaki Takimoto, Yoshio Kumazawa and Emilio Jirillo.


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Potential Use of Dietary Natural Products, Especially Polyphenols, for Improving Type-1 Allergic Symptoms


Kumazawa Y, Takimoto H, Matsumoto T and Kawaguchi K.


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Omega-6 and Omega-3 Polyunsaturated Fatty Acids and Allergic Diseases in Infancy and Childhood


Elizabeth A. Miles and Philip C Calder.


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Factors Affecting Residual Platelet Aggregation in Prasugrel Treated Patients


Dimitrios Alexopoulos, Ioanna Xanthopoulou, Angelos Perperis, Argyro Siapika, Katerina Stavrou, Evropi Tsoni, Periklis Davlouros and George Hahalis.


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What Fans the Fire: Insights into Mechanisms of Leptin in Metabolic Syndrome- Associated Heart Diseases


Maolong Dong and Jun Ren.


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Transactivation of ErbB Receptors by Leptin in the Cardiovascular System: Mechanisms, Consequences and Target for Therapy


Jerzy Bełtowski and Anna Jazmroz-Wiśniewska.


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Structural Insights into Chitinolytic Enzymes and Inhibition Mechanisms of Selective Inhibitors


Tian Liu, Lei Chen, Qiang Ma, Xu Shen and Qing Yang.


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Structure-based Design of Conformationally Flexible Reverse Transcriptase Inhibitors to Combat Resistant HIV


Ge-Fei Hao, Sheng-Gang Yang and Guang-Fu Yang.


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Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement


Lothar Esser, Chang-An Yu and Di Xia.


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ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development


Young Hee Choi, Ai-Ming Yu and Ai-Ming Yu.


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Structure-Based Drug Design to Overcome Drug Resistance: Challenges and Opportunities


Rafaela S. Ferreira1, Adriano D. Andricopulo and Adriano D Andricopulo.


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Novel Next-Generation Sequencing and Networks-Based Therapeutic Targets: Realistic and More Effective Drug Design and Discovery


Dimitrios H. Roukos, Giannis G. Baltogiannis, Christos S. Katsouras, Aris Bechlioulis, Katerina K. Naka, Charalambos Batsis, Theodore Liakakos and Lampros K Michalis.


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Endothelial Dysfunction and the Effects of TNF Inhibitors on the Endothelium in Psoriasis and Psoriatic Arthritis: A Systematic Review


Elizabeth A. Brezinski, Matthew R. Follansbee, Ehrin J. Armstrong and April W Armstrong.


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Effects of Biologic Agents and Other Disease-Modifying Antirheumatic Drugs on Cardiovascular Outcomes in Psoriasis and Psoriatic Arthritis: A Systematic Review


April W. Armstrong, Elizabeth A. Brezinski, Matthew R. Follansbee and Ehrin J Armstrong.


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Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents


Yan Lin, Zhi-Yi Chen and Feng Yang.


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Long-term Etanercept Therapy Favors Weight Gain and Ameliorates Cachexia in Rheumatoid Arthritis Patients: Roles of Gut Hormones and Leptin


Chih-Yen Chen, Chang-Youh Tsai, Pui-Ching Lee and Shou-Dong Lee.


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The Effect of First-in-Class Small Molecule RhoA Inhibitor, HL07, on the Phenylephrine-induced Artery Contraction


Yan Zhang, Jing Deng, Sheng Ma, Lin Xue, Jin Zhu, Wei-liang Zhu, Hua-liang Jiang, Jian Li and Li-yan Miao.


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Non-Systemic Drugs: A Critical Review


Dominique Charmot.


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Advancement of Targeted Ultrasound Contrast Agents and their Applications in Molecular Imaging and Targeted Therapy


Feng Yang, Zhi-Yi Chen and Yan Lin.


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Atorvastatin Sensitises Vascular Smooth Muscle Cells, but not Endothelial Cells, to TNF-α-induced Cell Death


Arturo Giordano, Simona Romano, Giovanna Nappo, Stefano Messina, Michele Polimeno, Nicola Corcione, Gaetano Calì, Paolo Ferraro, Mario Monaco, Nicola Zambrano and Maria Fiammetta Romano.


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Carotenoids and Cardiovascular Risk


Paola Giordano, Pietro Scicchitano, Manuela Locorotondo, Cosimo Mandurino, Gabriella Ricci, Santa Carbonara, Michele Gesualdo, Annapaola Zito, Annamaria Dachille, Paola Caputo, Roberta Riccardi, Giulia Frasso, Giuseppe Lassandro, Antonio Di Mauro and Marco Matteo Ciccone.


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A Computational Study of the Oligosaccharide Binding Sites in the Lectin-Like Domain of Tumor Necrosis Factor and the TNF-derived TIP Peptide


Alexander Dulebo, Rüdiger Ettrich, Rudolf Lucas and David Kaftan.


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Target-based Anti-angiogenic Therapy in Breast Cancer


Markus Wehland, Johann Bauer, Manfred Infanger and Daniela Grimm.


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Preclinical Safety and Pharmacokinetic Profile of 3K3A-APC, a Novel, Modified Activated Protein C for Ischemic Stroke


Patricia D. Williams, Berislav V. Zlokovic, John H. Griffin, Kent E. Pryor and Thomas P Davis.


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