E-Pub Articles Ahead of Print ::: Current Medicinal Chemistry

ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 23, 42 Issues, 2016


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Current Medicinal Chemistry

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 10th of 59 in Chemistry & Medicinal
  • 63th of 253 in Pharmacology & Pharmacy
  • 100th of 289 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK


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Current: 3.455
5 - Year: 3.792

E-Pub Articles Ahead of Print

Why Antidiabetic Vanadium Complexes are Not in the Pipeline of “Big Pharma” Drug Research? A Critical Review


Thomas Scior, Jose Antonio Guevara-Garcia, Quoc-Tuan Do, Philippe Bernard and S Laufer.


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Heat Shock Protein 70s as Potential Molecular Targets for Colon Cancer Therapeutics


Jennifer D. Black and Khosrow Rezvani.


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Recent Advances on Nitric Oxide in the Upper Airways


Mauro Maniscalco, Andrea Bianco, Gennaro Mazzarella and Andrea Motta.


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Hierarchy of knowledge translation: from health problems to ad-hoc drug design


Victor M. Castano and David Fajardo.


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Iron Acquisition Pathways as Targets for Antitubercular Drugs


Fiorella Meneghetti, Stefania Villa, Arianna Gelain, Daniela Barlocco, Laurent Roberto Chiarelli, Maria Rosalia Pasca and Luca Costantino.


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Emerging Roles of Protein S-Nitrosylation in Macrophages and Cancer Cells


Moran Benhar.


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Neurotrophins' Modulation by Olive Polyphenols


Marco Fiore, Mauro Ceccanti, Valentina Carito, Luigi Tarani, Giampiero Ferraguti and George N Chaldakov.


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Advances towards the Discovery of GPR55 Ligands


Paula Morales and Nadine Jagerovic.


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Pompe Disease and Autophagy: Partners in Crime, or Cause and Consequence?


M. Rodríguez-Arribas, J.M Bravo-San Pedro, R. Gómez-Sánchez, S.M.S. Yakhine-Diop, G. Martínez-Chacón, E. Uribe-Carretero, D.C.J. Pinheiro-De Castro, I. Casado-Naranjo, A. López de Munaín, M. Niso-Santano, J.M. Fuentes and RA González-Polo.


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In silico studies most employed in the discovery of new antimicrobial agents


F Tamay-Cach, ML Villa-Tanaca, JG Trujillo-Ferrara, D Alemán-González-Duhart, JC Quintana-Pérez, IA González-Ramírez and J Correa-Basurto.


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Functional Foods and Health Effects: A Nutritional Biochemistry Perspective.


F. Granado-Lorencio and E Hernández-Alvarez.


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Nutraceuticals, a New Challenge for Medicinal Chemistry


S. Sut, V. Baldan, M. Faggian, G. Peron and S Dall’Acqua.


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Nanomedicine for Intra-Articular Drug Delivery in Rheumatoid Arthritis


Hannah O'Mary, Inmaculada del Rincόn and Zhengrong Cui.


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Endocannabinoid System: A Promising Therapeutic Target for the Treatment of Haematological Malignancies?


Constantinos Giaginis, Eleftheria Lakiotaki, Penelope Korkolopoulou, Konstantinos Konstantopoulos, Efstratios Patsouris and Stamatios Theocharis.


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The Role of Cancer Biomarkers in HIV Infected Hosts


Domenico Galati and Serena Zanotta.


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Current Progresses and Trends in the Development of Progesterone Receptor Modulators


Wenlu Li, Xi Li, Bin Zhang, Chunmei Gao, Yuzong Chen and Yuyang Jiang.


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Microwave-assisted Formation of Organic Disulfides of Biochemical Significance


Debasish Sengupta, Babli Roy and Basudeb Basu.


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Pharmacological effects of niacin on acute hyperlipemia


Sergio Montserrat-de la Paz, Beatriz Bermudez, M Carmen Naranjo, Sergio Lopez, Rocio Abia and Francisco JG Muriana.


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A Review of Stapled Peptides and Small Molecules to Inhibit Protein–Protein Interactions in Cancer


Vidhya V Iyer.


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Human Embryonic and Induced Pluripotent Stem Cell Based Toxicity Testing Models: Future Applications in New Drug Discovery


Vaibhav Shinde, Poornima Sureshkumar, Isaia Sotiriadou, Jürgen Hescheler and Agapios Sachinidis.


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Promising Diabetes Therapy Based on the Molecular Mechanism for Glucose Toxicity: Usefulness of SGLT2 Inhibitors As Well As Incretin-Related Drugs


Hideaki Kaneto, Atsushi Obata, Masashi Shimoda, Tomohiko Kimura, Hidenori Hirukawa, Seizo Okauchi, Taka-Aki Matsuoka and Kohei Kaku.


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Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain


Katarzyna Popiolek-Barczyk and Joanna Mika.


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Adamantane – A Lead Structure for Drugs in Clinical Practice


Katarina Spilovska, Filip Zemek, Jan Korabecny, Eugenie Nepovimova, Ondrej Soukup Manfred Windisch and Kamil Kuca.


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G-quadruplex aptamers to human thrombin versus other direct thrombin inhibitors: the focus on mechanism of action and drug efficiency as anticoagulants


E Zavyalova, N Ustinov, A Golovin, G Pavlova and A Kopylov.


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Antiarrhythmic Mexiletine: a Review on Synthetic Routes to Racemic and Homochiral Mexiletine and its Enantioseparation


Alessia Catalano and Alessia Carocci.


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The Use of Stilbene Scaffold in Medicinal Chemistry and Multi-Target Drug Design


Elisa Giacomini, Sebastiano Rupiani, Laura Guidotti, Maurizio Recanatini and Marinella Roberti.


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Biphalin: The Foundation of Bivalent Ligands


Scott M. Cowell and Yeon Sun Lee.


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Development of the Third Generation EGFR Tyrosine Kinase Inhibitors for Anticancer Therapy


Weiyan Cheng, Jianhua Zhou, Xin Tian and Xiaojian Zhang.


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Macrocyclic Hepatitis C Virus NS3/4A Protease Inhibitors: An Overview of Medicinal Chemistry


Thanigaimalai Pillaiyar, Vigneshwaran Namasivayam and Manoj Manickam.


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From Bone Marrow to Cardiac Atrial Appendage Stem Cells for Cardiac Repair: A Review


Marc Hendrikx, Yanick Fanton, Leen Willems, Annick Daniels, Jeroen Declercq, Severina Windmolens, Karen Hensen, Remco Koninckx, Luc Jamaer, Jasperina Dubois, Dagmara Dilling-Boer, Jos Vandekerkhof, Filip Hendrikx, Eric Bijnens, Nick Heuts, Boris Robic, Virginie Bito, Marcel Ameloot, Paul Steels and Jean-Luc Rummens.


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Development of Anticancer Agents from Plant-derived Sesquiterpene Lactones


Yulin Ren, Jianhua Yu and A Douglas Kinghorn.


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Challenges in Chagas Disease Drug Discovery: A Review


Rocio Paucar, Elsa Moreno-Viguri and Silvia Pérez-Silanes.


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Prospects of applying enhanced semi-empirical QM methods for virtual drug design


Nusret Duygu Yilmazer and Martin Korth.


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Skp2 Inhibitors: Novel Anticancer Strategies


Yeongju Lee and Hyun-Suk Lim.


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Update on therapeutic approaches for rheumatoid arthritis


Eugénia Nogueira, Andreia Gomes, Ana Preto and Artur Cavaco-Paulo.


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Design and Synthesis of Dopaminergic Agonists


Maria Soledad Matute, Rosa Matute and Pedro Merino.


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Molybdenum Metallopharmaceuticals Candidate Compounds - The “Renaissance” of Molybdenum Metallodrugs


Anna Jurowska, Kamil Jurowski, Janusz Szklarzewicz, Bogusław Buszewski, Tatiana Kalenik and Wojciech Piekoszewski.


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Gold Complexes for Therapeutic Purposes: an Updated Patent Review (2010-2015)


Chiara Nardon, Nicolò Pettenuzzo and Dolores Fregona.


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Non-cholesterol Sterols in the Diagnosis and Treatment of Dyslipidemias: A Review


Lucía Baila-Rueda, Ana Cenarro and Fernando Civeira.


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An Update on Phytochemicals Substances in Molecular Target Therapy of Cancer: Potential Inhibitory Effect on Telomerase Activity


Abbas Alibakhshi, Javad Ranjbari, Yones Pilehvar-Soltanahmadi, Marzieh Nasiri, Mahdie Mollazade and Nosratollah Zarghami.


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Advances in Nanocarriers for Anticancer Drugs Delivery


Imran Ali, Mohammad Nadeem Lone, Mohd. Suhail and Sofi Danish Mukhtar.


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A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines


Wojciech Filipiak, Pawel Mochalski, Anna Filipiak, Clemens Ager, Raquel Cumeras, Cristina E. Davis, Agapios Agapiou, Karl Unterkofler and Jakob Troppmair.


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Myeloperoxidase as a Target for Treatment of Inflammatory Syndromes: Mechanisms and Structure Activity Relationships of Inhibitors


Jalal Soubhye, Iyas Aldib, Cédric Delporte, Martine Prévost, François Dufrasne and Pierre Van Antwerpen.


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Standardization of Epitopes for Human Chorionic Gonadotropin (hCG) Immunoassays


Peter Berger and Adrian Lapthorn.


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The Plant Resources, Structure Characteristics, Biological Activities and Synthesis of Pyranoflavonoids


Bao Yang, Jiali Yang, Yupeng Zhao, Huiling Liu and Yueming Jiang.


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Targeting Stim and Orai proteins as an alternative approach in anticancer therapy


Francesco Moccia, Estella Zuccolo, Valentina Poletto, Ilaria Turin, Germano Guerra, Paolo Pedrazzoli, Vittorio Rosti, Camillo Porta and Daniela Montagna.


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Current Trends on Antipsychotics: Focus on Asenapine


Donatella Marazziti, Armando Piccinni, Stefano Baroni, Francesco , Mungai, Silvio Presta, Federico Mucci and Liliana Dell'Osso.


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Recent Trends in the Discovery of Small Molecule Blockers of Sodium Channels


Roberta Gualdani, Maria Maddalena Cavalluzzi and Giovanni Lentini.


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Naturally Occurring Wound Healing Agents: An Evidence-Based Review


E.G. Karapanagioti and AN Assimopoulou.


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Biosimilar filgrastim in autologous peripheral blood hematopoietic stem cell mobilization and post-transplant hematologic recovery


F Marchesi and A Mengarelli.


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Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy


Giampietro Sgaragli, Maria Frosini, Simona Saponara and Federico Corelli.


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Natural AMPK Activators: An Alternative Approach for the Treatment and Management of Metabolic Syndrome


Hitender Sharma and Sunil Kumar.


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Editorial: Mechanisms and Therapeutic Strategies for Major Neurological Disorders: Current Advances and Future Perspectives


Weihai Ying.


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