E-Pub Articles Ahead of Print ::: Current Medicinal Chemistry

ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)

Volume 22, 38 Issues, 2015

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Current Medicinal Chemistry

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  • 9th of 58 in Chemistry & Medicinal
  • 49th of 254 in Pharmacology & Pharmacy
  • 96th of 291 in Biochemistry & Molecular Biology

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Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge

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E-Pub Articles Ahead of Print

The changing face of Hepatitis C: Recent Advances on HCV Inhibitors Targeting NS5A
Diwakar Rai, Liu Wang, Xuemei Jiang, Peng Zhan, Haiyong Jia, Erik De Clercq and Xinyong Liu
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Exit from Mycobacterial Dormancy: A Structural Perspective
Flavia Squeglia, Alessia Ruggiero and Rita Berisio
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Shutting Down the Furnace: Preferential Killing of Cancer Cells with Mitochondrial-targeting Molecules
Cláudia M. Deus, Gabriela L. Santos, Rute Loureiro, Ignacio Vega-Naredo, Henrique Faneca and Paulo J. Oliveira
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Food Addiction Spectrum: A Theoretical Model from Normality to Eating and Overeating Disorders
Armando Piccinni, Donatella Marazziti, Federica Vanelli, Caterina Franceschini, Stefano Baroni, Davide Costanzo, Stefano Baroni, Ivan Mirko Cremone, Antonello Veltri and Liliana Dell’Osso
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Glycation and Hypoxia: Two Key Factors for Adipose Tissue Dysfunction
Paulo Matafome, Tiago Rodrigues and Raquel Seiça
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Biological Therapies: Effects of Proinflammatory Pathways and their Inhibition on the Myocardium of RA Patients
Florian Obermair and Herwig Pieringer
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Trends in Mitochondrial Therapeutics for Neurological Disease
Ana Leitão-Rocha, Pedro Guedes-Dias, Brígida R. Pinho and Jorge M. A. Oliveira
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Tumor Necrosis Factor Blocking Therapy and Congestive Heart Failure in Patients with Inflammatory Rheumatic Disorders: A Systematic Review
S. C. Heslinga, A. M. Van Sijl, K. De Boer, V. P. Van Halm and M. T. Nurmohamed
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Editorial: Switching to Biological Agents in Autoimmune and Autoinflammatory Disorders: Current Targets and Therapy
Armen Yuri Gasparyan
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Editorial: Mechanisms and Therapeutic Strategies for Major Neurological Disorders: Current Advances and Future Perspectives
Weihai Ying
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Currently Used Biologic Agents in the Management of Behçet’s Syndrome
Caner Saygin, Didem Uzunaslan and Gulen Hatemi
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Structure and function of prokaryotic UDP-glucose pyrophosphorylase, a drug target candidate
M. Álvaro Berbís, José María Sánchez-Puelles, F. Javier Cañada and Jesús Jiménez-Barbero
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Tissue-specific Glucocorticoid Signaling May Determine the Resistance Against Glucocorticoids in Autoimmune Diseases
Á. Szappanos, Z. Nagy, B. Kovács, G. Poór, M. Tóth, K. Rácz, E. Kiss and A. Patócs
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Purinergic P2X Receptors: Structural and Functional Features Depicted by X-Ray and Molecular Modelling Studies
Leanne Grimes and Mark T Young
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Current Developments in Antimicrobial Surface Coatings for Biomedical Applications
J. J.T.M. Swartjes, P. K. Sharma, T. G. van Kooten, H. C. van der Mei, M. Mahmoudi, H. J. Busscher and E. T.J. Rochford
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Polymers and Formulation Strategies of Nanofibrous Systems for Drug Delivery Application and Tissue Engineering
I. Sebe, B. Kállai-Szabó, R. Zelkó and D. Szabó
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Glucocorticoids in Patients with Rheumatic Diseases: Friends or Enemies of Bone?
Fedra Ciccarelli, Massimo De Martinis and Lia Ginaldi
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Bioactivation of Drugs: Enzymes, Reactive Metabolites and Adverse Reactions
Hilmi Orhan
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An Overview of the Selectivity and Efficiency of the Bacterial Carbonic Anhydrase Inhibitors
C. Capasso and C. T. Supuran
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p38 MAPK: A Potential Target of Chronic Pain
X. Lin, M. Wang, J. Zhang and R. Xu
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Editorial: Emerging biomarkers for drug development in Amyotrophic Lateral Sclerosis
Sebastiano Cavallaro
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A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy
X. Xu, L. Xiao, P. Xiao, S. Yang, G. Chen, F. Liu, Y.S. Kanwar and L. Sun
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Disturbed Tryptophan Metabolism in Cardiovascular Disease
H. Mangge, I. Stelzer, E.Z. Reininghaus, D. Weghuber, T.T. Postolache and D. Fuchs
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Editorial: Cardiovascular drug therapy in paediatric age: from metabolomics to clinical practice
Bassareo PP and Fanos V
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Editorial: Prevention of microbial biofilms - the contribution of micro and nanostructured materials
Alexandru Mihai Grumezescu and Carmen Mariana Chifiriuc
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EDITORIAL: New Insight into Lipid Disorders
Valentina Pallottini
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Adipocytes Contribute to Resistance of Human Melanoma Cells to Chemotherapy and Targeted Therapy
M. Chi, J. Chen, Y. Ye, Hsin-Yi Tseng, F. Lai, K.H. Tay, L. Jin, S.T. Guo, C.C. Jiang and X.D. Zhang
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P38 MAPK Contributes to Resistance and Invasiveness of HER2- Overexpressing Breast Cancer
S.M. Donnelly, E. Paplomata, B.M. Peake, E. Sanabria, Z. Chen and R. Nahta
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The Functional Logic of Cytosolic 5’-Nucleotidases
Piero L Ipata and Francesco Balestri
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Biophysical Characterization of Glycodendrimers As Nano-carriers for HIV Peptides
M. Ionov, K. Ciepluch, B.R. Moreno, D. Appelhans, J. Sánchez-Nieves, R. Gómez, F.J. de la Mata, M.A. Muñoz-Fernández and M. Bryszewska
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Human Galectin-3 Selective and High Affinity Inhibitors. Present State and Future Perspectives
R. Téllez-Sanz, L. García-Fuentes and A. Vargas-Berenguel
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Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53wildtype JVM-2 But Not Towards p53mutated BJAB Leukemic Cells
R. Voltan, P. Secchiero, B. Ruozi, L. Caruso, F. Forni, M. Palomba, G. Zauli and M.A. Vandelli
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MEK Inhibition Increases Lapatinib Sensitivity Via Modulation of FOXM1
S.S. Gayle, R.C. Castellino, M.C. Buss and R. Nahta
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1,2,4-Oxadiazoles Identified by Virtual Screening and their Non-Covalent Inhibition of the Human 20S Proteasome
X. Maréchal, E. Genin, L. Qin, O. Sperandio, M. Montes, N. Basse, N. Richy, M.A. Miteva, M. Reboud-Ravaux, J. Vidal and B.O. Villoutreix
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Insulin Secretion and Interleukin-1β Dependent Mechanisms in Human Diabetes Remission After Metabolic Surgery
Chih-Yen Chen, Wei-Jei Lee, A. Asakawa, N. Fujitsuka, Keong Chong, Shu-Chun Chen, Shou-Dong Lee and A. Inui
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Serenoa Repens, Lycopene and Selenium: A Triple Therapeutic Approach to Manage Benign Prostatic Hyperplasia
L. Minutoli, A. Bitto, F. Squadrito, H. Marini, N. Irrera, G. Morgia, A. Passantino and D. Altavilla
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Anti-Inflammatory and Antioxidant Effects of Resveratrol in Healthy Smokers A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial
S. Bo, G. Ciccone, A. Castiglione, R. Gambino, F. De Michieli, P. Villois, M. Durazzo, P. Cavallo-Perin and M. Cassader
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Developing FGFR4 Inhibitors As Potential Anti-Cancer Agents Via In Silico Design, Supported by In Vitro and Cell-Based Testing
H.K. Ho, G. Németh, Y.R. Ng, E. Pang, C. Szántai-Kis, L. Zsákai, N. Breza, Z. Greff, Z. Horváth, J. Pató, I. Szabadkai, B. Szokol, F. Baska, L. Orfi, A. Ullrich, G. Kéri and B.T. Chua
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Design, SAR, Angiogenic Activities Evaluation and Pro-Angiogenic Mechanism of New Marine Cyclopeptide Analogs
J. Li, X. Lu, Q. Wu, G. Yu, Z. Xu, L. Qiu, Z. Pei, Y. Lin and J. Pang
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Prostate Cancer, miRNAs, Metallothioneins and Resistance to Cytostatic Drugs
V. Pekarik, J. Gumulec, M. Masarik, R. Kizek and V. Adam
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Increased Akt Signaling Resulting from the Loss of Androgen Responsiveness in Prostate Cancer
J. Dulinska-Litewka, J.A. McCubrey and P. Laidler
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Inhaled Muscarinic Acetylcholine Receptor Antagonists for Treatment of COPD
P. Montuschi, F. Macagno, S. Valente and L. Fuso
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State of the Art of the Therapeutic Perspective of Sorafenib Against Hematological Malignancies
G. Zauli, R. Voltan, V. Tisato and P. Secchiero
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Therapeutic Monoclonal Antibodies: Strategies and Challenges for Biosimilars Development
Begoña Calvo and Leyre Zuñiga
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Physico-Chemical Properties Mediating Reproductive and Developmental Toxicity of Engineered Nanomaterials
Luisa Campagnolo, Micol Massimiani, Andrea Magrini, Antonella Camaioni and Antonio Pietroiusti
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Alkyl Hydroxybenzoic Acid Derivatives that Inhibit HIV-1 Protease Dimerization
O.A. Flausino Jr., L. Dufau, L.O. Regasini, M.S. Petrônio, D.H.S. Silva, T. Rose, V.S. Bolzani and M. Reboud-Ravaux
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Oxidized-LDL and Paraoxonase-1 As Biomarkers of Coronary Artery Disease in Patients with Sleep-Disordered Breathing
F.S. Hackenhaar, D. Martinez, T.M. Medeiros, C. Klein, P.V.G. Alabarse, M.V. Wainstein, S.C. Gonçalves and M.S. Benfato
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pKa, Zinc- and Serum Albumin-Binding of Curcumin and Two Novel Biologically- Active Chemically-Modified Curcumins
Yu Zhang, Lorne M. Golub, Francis Johnson and Arnold Wishnia
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Design, Synthesis and Biological Activity of New Polyenolic Inhibitors of Matrix Metalloproteinases: A Focus on Chemically-Modified Curcumins
Yu Zhang, Ying Gu, Hsi-Ming Lee, Elena Hambardjieva, Kveta Vrankova, Lorne M. Golub and Francis Johnson
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Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments
A. Banerjee and O. Prante
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Targeting DNA Topoisomerase I with Non-Camptothecin Poisons
G.L. Beretta, V. Zuco, P. Perego and N. Zaffaroni
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