Advances in Nanomaterials for Diagnosis and Therapy of Leukemia

ISSN: 1877-9131 (Online)
ISSN: 1877-9123 (Print)


Volume 4, 2 Issues, 2014


Download PDF Flyer




Recent Patents on Nanomedicine

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Victor Manuel Castano Meneses
Center of Applied Physics and Advanced Technology
National Autonomous University of Mexico
Juriquilla Campus
Queretaro
México


View Full Editorial Board

Subscribe Purchase Articles Order Reprints


Advances in Nanomaterials for Diagnosis and Therapy of Leukemia

Author(s): Swati S. Vyas and Vandana B. Patravale

Affiliation: Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400019, India.

Abstract

Numerous efforts in oncological scientific research have revealed many causative facets of leukemia, explaining mechanistic aspects of disease progression at the molecular scale. Reports record over 40,000 new cases of patients afflicted with myeloid and lymphocytic leukemia annually worldwide. Early diagnosis and quick therapy are advantageous in effective treatment. Conventional methods mainly rely on blood cell counts and bone marrow biopsies for detection but these are inefficient in accurately diagnosing leukemia. Contemporary research has employed core nanotechnology in designing more efficient diagnostic and theranostic systems for leukemia. In such systems, biological markers and genetic materials such as siRNA and peptides tagged with nanoparticles (dendrimers, aptamers, and metal nanoparticles) form the fundamental elements that work at the molecular level and confer a high degree of specificity for recognition and capture, and in a therapeutic context, cytotoxicity for eradication of cancerous cells. We review current research and patented technologies that focus on nanomaterials as promising tools in detection and treatment of chronic and acute leukemia.

Keywords: Diagnosis, leukemia, nanomedicine, theranosis, treatment.

Download Free Rights and Permissions

Article Details

Volume: 3
Issue Number: 2
First Page: 99
Last Page: 104
Page Count: 6
DOI: 10.2174/1877912304666140201000322
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science