Optical Coherence Tomography: from Research to Clinical Practice
Gioel Gabrio Secco, Alessandro Lupi, Matteo Ghione, Gianni Dall'Ara, Rosario Parisi, Alessio Mattesini, Rossella Fattori, Andrea Rognoni, Giuseppe De Luca, Giulia Genoni, Paolo Nicola Marino and Carlo Di MarioAffiliation:
Department of Clinical and Experimental Medicine, University of Eastern Piedmont, Novara, Italy.
AbstractAngiography has been the cornerstone tool to assess coronary anatomy, leading to a rapid development of percutaneous revascularisation techniques. Despite the widespread dissemination and high reproducibility, angiography alone can only provide a limited analysis of lumen profile without the possibility to disclose vessel wall characteristics and composition of coronary lesions. Intracoronary imaging techniques have been developed to overcome these limitations. Intravascular ultrasound (IVUS) was the first intracoronary imaging modality introduced two decades before , followed more than a decade after by optical coherence tomography (OCT), a light based technology. This article presents the current status in the technical background of OCT imaging in the areas of research development and clinical practice, focusing on future developments of related patent forms.
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