Computed Tomography Imaging of the Coronary Arteries: State of the Art Applications and Recent Patents
Alon Schaffer, Ettore Cassetti, Maria Grazia Di Iovine, Lucia Barbieri, Andrea Rognoni, Gioel Gabrio Secco, Maurizio Lazzero, Angelo Sante Bongo, Italo Porto and Alessandro LupiAffiliation:
Department of Clinical and Experimental Medicine, University of Eastern Piedmont, "Maggiore della Carita" Hospital, Novara, Italy.
AbstractComputed tomography (CT), is important in diagnosing and managing many medical illness, including coronary artery disease. However, some potential disadvantages are associated with this kind of imaging, like the exposure to potentially harmful radiation or the hypersensitivity or nephrotoxic reactions to the iodinated contrast medium. In order to overcome these potential problems imaging technologies are changing rapidly and new- generation computed tomography (NGCCT) scanners may offer substantial advantages over CT and other imaging methods currently used, with shorter imaging times and protocols dedicated to reduce radiation doses with improved accuracy. Current CT scanners can very accurately diagnose CAD requiring intervention in most patients, but NGCCT may further benefit in some “difficult” patients from whom often suboptimal imaging is produced (e.g. obese patients, patients with high or irregular heart rates, and patients who have high coronary calcium burden or a previous stent or bypass graft). In this review we focused our attention over the recent development of NGCCT for the assessment of patients with coronary artery disease (CAD).
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