Patents in the Therapeutic Recombinant Protein Production Using Mammalian Cells

ISSN: 2212-4012 (Online)
ISSN: 1872-2083 (Print)

Volume 10, 3 Issues, 2016

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Recent Patents on Biotechnology

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Nikolaos Labrou
Laboratory of Enzyme Technology, Department of Biotechnology
Agricultural University of Athens Iera Odos 75, Gr-118 55

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Patents in the Therapeutic Recombinant Protein Production Using Mammalian Cells

Recent Patents on Biotechnology, Volume 7 (E-pub ahead of print)

Author(s): Virgínia Picanço-Castro, Marcela Cristina Corrêa de Freitas, Aline de Sousa Bomfim and Elisa Maria de Sousa Russo.

Affiliation: Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil


The industrial production of recombinant proteins requires, preferentially, the generation of stable cell lines expressing proteins in a quickly and reproducibly manner as well as with relative ease. Different methods are used to insert an exogenous DNA into the host cell and the choice of the producing cell is of paramount importance for the efficient production and quality of the recombinant protein. This review addresses the advances in recombinant proteins production in mammalian cell lines, according to the key patents in the last 20 years


Recombinant protein, mammalian expression system, patents in biopharmaceuticals.

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Article Details

Volume: 7
First Page: 1
Last Page: 7
Page Count: 7
DOI: 10.2174/1872208307666131202191925
Global Biotechnology Congress 2016Drug Discovery and Therapy World Congress 2016

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