Cannabinoids (CBD, CBDHQ and THC): Metabolism, Physiological Effects, Electron Transfer, Reactive Oxygen Species and Medical Use

ISSN: 2210-3163 (Online)
ISSN: 2210-3155 (Print)


Volume 4, 4 Issues, 2014


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The Natural Products Journal

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Editor-in-Chief:
Francesco Epifano
Università "G. D'Annunzio"
Chieti-Pescara, Chieti Scalo (CH)
Italy


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Cannabinoids (CBD, CBDHQ and THC): Metabolism, Physiological Effects, Electron Transfer, Reactive Oxygen Species and Medical Use

Author(s): Peter Kovacic and Ratnasamy Somanathan

Affiliation: Department of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182-1030 USA.

Abstract

In recent years, cannabinoids, particularly cannabidiol (medical marijuana), have attracted considerable attention. This review addresses various aspects including metabolism. Other cannabinols of interest are THC and the hydroxyl quinone metabolite. Physiological influences are addressed, particularly anticancer action, receptors, antioxidants, and neurological effects. A unifying mechanism is invoked based on electron transfer, reactive oxygen species and oxidative stress.

Keywords: Cannabinoids, cannabidiol, metabolism, therapy, toxicity, electron transfer, reactive oxygen species.

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Article Details

Volume: 4
Issue Number: 1
First Page: 47
Last Page: 53
Page Count: 7
DOI: 10.2174/2210315504666140512220028
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