Cannabinoids (CBD, CBDHQ and THC): Metabolism, Physiological Effects, Electron Transfer, Reactive Oxygen Species and Medical Use
Peter Kovacic and Ratnasamy SomanathanAffiliation:
Department of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182-1030 USA.
AbstractIn recent years, cannabinoids, particularly cannabidiol (medical marijuana), have attracted considerable attention. This review addresses various aspects including metabolism. Other cannabinols of interest are THC and the hydroxyl quinone metabolite. Physiological influences are addressed, particularly anticancer action, receptors, antioxidants, and neurological effects. A unifying mechanism is invoked based on electron transfer, reactive oxygen species and oxidative stress.
Cannabinoids, cannabidiol, metabolism, therapy, toxicity, electron transfer, reactive oxygen species.
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