GC-MS Determination of Major Bioactive Constituents and Anti-oxidative Activities of Aqueous Extracts of Cinnamomum burmannii Blume Stem

ISSN: 2210-3163 (Online)
ISSN: 2210-3155 (Print)


Volume 4, 4 Issues, 2014


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Editor-in-Chief:
Francesco Epifano
Università "G. D'Annunzio"
Chieti-Pescara, Chieti Scalo (CH)
Italy


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GC-MS Determination of Major Bioactive Constituents and Anti-oxidative Activities of Aqueous Extracts of Cinnamomum burmannii Blume Stem

Author(s): Gabriel A. Akowuah, Mariam Ahmad, Soo C. Tan and Mun F. Yam

Affiliation: Faculty of Pharmaceutical Sciences, UCSI University, 56000, Kuala Lumpur, Malaysia.

Abstract

The aim of this study was to determine the major boactive constituents, trans-cinnamic acid and transcinnamaldehyde, and anti-oxidative activities of 50% aqueous methanol and water extracts of Cinnamomum burmannii Blume stem bark. Gas chromatography-mass spectrometry (GC-MS) was used to analyse the extracts. The content of trans-cinnalmadeyde quantified in the 50% aqueous methanol and water extracts were 50.14 µg/mg and 12.83 µg/mg of dry extract, respectively. The content of trans-cinnamic acid quantified in the water extract was 49.7 µg/mg of dry extract. Trans-cinnamic acid was not detected in the 50% aqueous methanol (v/v) extract. The extracts demonstrated in vitro antioxidative effects with the 50% aqueous methanol extract being more potent than the water extract.

Keywords: Cinnamomun burmannii, GC-MS analysis, cinnamaldehyde, cinnamic acid, anti-oxidative activity.

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Article Details

Volume: 3
Issue Number: 4
First Page: 243
Last Page: 248
Page Count: 6
DOI: 10.2174/2210315504666140305231430
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