[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)


Volume 14, 14 Issues, 2014


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[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

Author(s): Rajesh O. Bora, Bashir Dar, Vidya Pradhan and Mazahar Farooqui

Affiliation: Post Graduate and Research centre, Maulana Azad College, Aurangabad, and Indian Institute of Integrative Medicine Jammu 180001.

Abstract

In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.

Keywords: Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles, synthetic methods.

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Article Details

Volume: 14
Issue Number: 4
First Page: 355
Last Page: 369
Page Count: 15
DOI: 10.2174/1389557514666140329200745
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