Immunological Aspects Of Metritis In Dairy Cows: A Review

ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)


Volume 14, 4 Issues, 2014


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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

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Editor-in-Chief:
Emilio Jirillo
Universitá degli Studi di Bari
Dipartimento di Clinica Medica
Immunologia e Malattie Infettive
Sezione di Microbiologia e Immunologia
Piazza Giulio Cesare-Policlinico
Bari
Italy


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Immunological Aspects Of Metritis In Dairy Cows: A Review

Author(s): Marianna Pantaleo, Annalisa Rizzo, Giovanni D’Onghia, Gianfranco D’Onghia, Maria Roncetti, Mariagrazia Piccinno, Maddalena Mutinati, Michele Roberto Terlizzi and Raffaele Luigi Sciorsci

Affiliation: Department of the Emergency and Organ Transplantation (D.E.T.O.) – Section of Veterinary Clinics and Animal

Abstract

This paper reviews puerperal metritis in the cow, particularly the complex and multi-factorial pathogenesis characterized by an altered cross-talk among infectious agents, endocrine and immune systems. Uterine infections impair fertility and is one of the main causes of economic losses in dairy production. The early postpartum is a period characterized by an increased exposition to infectious agents and the disruption of the metabolic homeostasis, leading to endocrine and immunologic disorders. Dysregulation of uterine defence mechanisms results in the development of metritis. Because there is a complex interaction between of infectious, endocrine and immune factors during metritis, there is need to use safer and cheaper drugs which are able to strengthen the anti-infective actions of the routine therapies

Keywords: Dairy cow, immunity, postpartum, uterus inflammatory diseases

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Article Details

Volume: 14
First Page: 1
Last Page: 10
Page Count: 10
DOI: 10.2174/1871530314666140527142346
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