Affiliation: Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, C/ Madre de Dios, 51. 26006 Logrono (La Rioja). Spain.
α-Methylisoserine, a chiral acyclic quaternary β-amino acid, has been used to mimic secondary structures, when it is incorporated in a homogeneous β2,2-dipeptide. In particular, the observed folded conformations in aqueous solution can be regarded as mimics of β-turn.