The Role of Tissue Engineering in Achilles Tendon Repair: A Review
Current Stem Cell Research & Therapy ,
Varun Sahni, Saket Tibrewal, Lianne Bissell and Wasim S. KhanAffiliation:
59 Elmstead Lane, Chislehurst, Kent BR7 5EQ. UK.
AbstractAchilles tendon injuries are common but complex in nature. Healing occurs via scar tissue formation leading to poor patient outcomes. Currently surgical and non-surgical treatment leads to suboptimal tendon healing and has complications. Tissue engineering is an advancing field that can either augment surgical repair or provide an alternative method for Achilles tendon repair. This article will explore the principles behind tissue engineering in Achilles tendon repair. Furthermore it will describe the current literature regarding the different types of stem cells used in Achilles tendon repair, how different growth factors augment tendon repair, as well as the role of biomaterials in tissue engineering.
Achilles tendon, growth factors, stem cells, tissue engineering.
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