Incidentally Detected Increased Fdg Uptake In Bowel And Its Correlation With Hystopathological Data: Our Experience In A Case Series Study

ISSN: 1874-4729 (Online)
ISSN: 1874-4710 (Print)


Volume 7, 2 Issues, 2014


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Incidentally Detected Increased Fdg Uptake In Bowel And Its Correlation With Hystopathological Data: Our Experience In A Case Series Study

Author(s): Ilaria Grassi, Paolo Castellucci, Cristina Nanni, Pietro Ghedini, valentina ambrosini, vincenzo allegri, gian carlo montini, pier luigi guidalotti and stefano fanti

Affiliation: Ilaria Grassi, MD U.O. Medicina Nucleare, Policlinico Sant Orsola- Malpighi,Bologna, Italy

Abstract

When an intense intestinal FDG accumulation is present, especially if focal, it can be referred to either physiological intestinal activity or bowel disease, thus leading to a radical change in patient’s prognosis. Within a year, we recommended a colonoscopy to 103 of 7365 patients who were subjected to a total body FDG PET/CT and in a case-series study we re-evaluated the patients and their lesions if already investigated with colonoscopy and biopsy. Only 18 patients were included in our study, but in none of them biopsy was negative and 3 adenocarcinomas, 8 adenomas, 5 inflammatory pattern, 1 hyperplastic polyp and 1 eosinophylic infiltrate were diagnosed. In 16 patients, no suspicion was present and diagnosis was absolutely incidental. Besides, among the three major groups (adenocarcinomas, adenomas and phlogosis), SUVmax values were significantly different. Adenocarcinomas are mainly linked with SUVmax higher than 8 and size larger than 15 mm. In detecting inflammatory localizations, FDG PET SE is of 100% if SUVmax is higher than 4. SE is lower in detecting adenomas, being 71.4% if they are larger than 6 mm and 50% if SUVmax is lower than 4.9. CCR is still the second leading cause of cancer death, for this reason in many countries screening programs have been approved and colonoscopy is considered the golden standard. PET/CT cannot be considered as a screening test, but if it incidentally reveals intestinal abnormalities, this data cannot be underestimated and colonoscopy is highly recommended


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Article Details

Volume: 7
First Page: 1
Page Count: 1
DOI: 10.2174/1874471007666140613111058
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