Cobalt Supported on MWCNTs: A Green and Recyclable Catalyst for the Synthesis of 2-Aryl-2,3-Dihydroquinazolin-4(1H)-ones under Dry Media
Current Organic Synthesis,
Volume 10 (E-pub ahead of print)Author(s): Javad Safari
and Soheila Gandomi-Ravandi
Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I.R. IRAN.
AbstractTransition metals-CNT nanocomposites revealed high catalytic activity as a novel and reusable promoting nanocatalyst in the synthesis of quinazolinone heterocyclic compounds. The eco-friendly synthesis was carried out by reacting 2-aminobenzamide (anthranilamide) and various substituted aldehydes without any solvent in the presence of a small amount of the nanocatalyst. These nanocomposites are found to be actual active for the synthesis of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones under solvent free conditions. The use of heterogeneous acid catalyst makes this method quite simple, more convenient, green, and practical. This method presents a significant technique toward an environmentally synthesis of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones.
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