N-Heterocyclic Carbenes (NHCs) in Asymmetric Organocatalysis

ISSN: 2213-3380 (Online)
ISSN: 2213-3372 (Print)


Volume 1, 2 Issues, 2014






Current Organocatalysis

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Bimal K. Banik
Department of Chemistry
College of Science & Mathematics
The University of Texas-Pan American
1201 West University Drive
Edinburg, Texas 78539
USA


View Full Editorial Board

Subscribe Purchase Articles Order Reprints


N-Heterocyclic Carbenes (NHCs) in Asymmetric Organocatalysis

Author(s): Seema Dwivedi, Sumanta Gupta and Sajal Das

Affiliation: Department of Chemistry, University of North Bengal, Darjeeling 734 013, India.

Abstract

Asymmetric synthesis is a crucial and valuable branch of synthetic chemistry. Organocatalytic methods of synthesis are known for their greener approach towards scientific developments. These involve simple molecules as catalysts that are less sensitive and can be easily and effectively employed in various systems with simple reaction conditions. In the recent past organocatalytic asymmetric syntheses have thus grasped the attentions of chemists worldwide. Remarkable contributions of N-heterocyclic carbenes have proved them to be valuable addition in this arena affording new possibilities and enabling a range of unique synthetic transformations that are otherwise inaccessible. High enantioselectivity levels have been achieved in many cases including umpolung reactions such as benzoin condensation, Stetter reaction, reactions involving enolates and homoenolates, etc. This review summarizes the recent developments in the reactions that can be carried out with NHC organocatalysts.




Keywords: Asymmetry catalysis, breslow intermediate, benzoin condensation, C–C bond formations, cycloaddition, organocatalysis, desymmetrisation, homoenolates, N-heterocyclic carbenes, Stetter reaction, umpolung reaction.

Download Free Rights and Permissions

  
  



Article Details

Volume: 1
Issue Number: 1
First Page: 13
Last Page: 39
Page Count: 27
DOI: 10.2174/2213337201999131230123630
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science