Caffeine and Suicide: A Systematic Review

ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)

Volume 14, 10 Issues, 2015

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CNS & Neurological Disorders - Drug Targets

Formerly: Current Drug Targets - CNS & Neurological Disorders

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Stephen D. Skaper
Department of Pharmaceutical and Pharmacological Sciences
University of Padova

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Caffeine and Suicide: A Systematic Review

CNS & Neurological Disorders - Drug Targets, 13(6): 937-944.

Author(s): Adriana Cardoso Silva, Natalia Pinho de Oliveira Ribeiro, Alexandre Rafael de Mello Schier, Valeska Martinho Pereira, Marina Machado Vilarim, Tamires Marinho Pessoa, Oscar Arias-Carrion, Sergio Machado and Antonio Egidio Nardi.

Affiliation: Institute of Psychiatry - Federal University of Rio de Janeiro. Laboratory of Panic and Respiration. Rua Visconde de Piraja, 407/702. Rio de Janeiro, RJ. CEP 22410-003, Brazil.


Suicide is considered a deliberate act initiated and concluded by a person with full knowledge or expectation of a fatal result, and one of the main symptoms of depression. An individual’s conscious and excessive ingestion of a damaging substance is also considered to be an attempted suicide. Despite limited knowledge of caffeine abuse, deaths from overdose of caffeine have been reported in the literature. Thus, this study aims to review the existing literature on caffeine consumption and suicide attempts and deaths, investigating the relation between caffeine consumption and suicide attempts and deaths. We found 24 studies that discuss the relationship between caffeine and suicide. The findings revealed that, despite being an addictive substance and potentially fatal in higher doses, caffeine was still a rare factor in a number of studies concerning its relation with suicide attempts and death. The majority of the research found in this study was of the case study type. Furthermore, the majority of studies focus on the assistance offered to the victim and the procedures undertaken to control the bodily damage created. The existing studies indicate the substance may act as either a direct or an indirect agent in suicide. Therefore, a better understanding of how caffeine may be linked to suicide is crucial for its prevention.


Caffeine, drug abuse, prevention, suicide.

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Article Details

Volume: 13
Issue Number: 6
First Page: 937
Last Page: 944
Page Count: 8
DOI: 10.2174/1871527313666140612123656

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