Deep Brain Stimulation: A New Treatment in Mood and Anxiety Disorders

ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)

Volume 13, 10 Issues, 2014

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CNS & Neurological Disorders - Drug Targets

Formerly: Current Drug Targets - CNS & Neurological Disorders

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Stephen D. Skaper
Department of Pharmaceutical and Pharmacological Sciences
University of Padova

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Deep Brain Stimulation: A New Treatment in Mood and Anxiety Disorders

Author(s): B Velasques, C Diniz, S Teixeira, C Cartier, C Peressutti, F Silva, M de Carvalho, A Novaes, J Bittencourt, A E Nardi, E Cheniaux, L Basile, M Cagy, R Piedade and P Ribeiro

Affiliation: Institute of Psychiatry, Federal University of Rio de Janeiro, Brazil


This article considered already existing studies about Deep Brain Stimulation in Mood and Anxiety Disorders. In particular, articles regarding Obsessive-Compulsive Disorder and Major Depression were mostly analyzed due to the lack of researches about other types of Mood and Anxiety Disorders. We concentrated on the target areas where Deep Brain Stimulation was most commonly applied and on the effects of this measure on treatment-refractory patients. The results found showed that the stimulation of the nucleus accumbens, the subgenual cingulate cortex and the ventral capsule/ventral striatum positively influences the development of the disorders investigated, sometimes showing the complete remission of the symptoms. Although Deep Brain Stimulation was overall found to be a promising and safe treatment for Mood and Anxiety Disorders, there are not enough studies proving its efficacy in wide samples and in the presence of more complex variables

Keywords: Depression, deep brain stimulation, obsessive-compulsive disorders

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Article Details

Volume: 13
First Page: 1
Last Page: 11
Page Count: 11
DOI: 10.2174/1871527313666140612122929

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