Bupropion in the Depression-Related Sexual Dysfunction: A Systematic Review

ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)


Volume 13, 10 Issues, 2014


Download PDF Flyer




CNS & Neurological Disorders - Drug Targets

Formerly: Current Drug Targets - CNS & Neurological Disorders

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 96th of 254 in Pharmacology & Pharmacy

Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Stephen D. Skaper
Department of Pharmaceutical and Pharmacological Sciences
University of Padova
Padova
Italy


View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 2.702
5 - Year: 3.298

Bupropion in the Depression-Related Sexual Dysfunction: A Systematic Review

Author(s): V M Pereira, O Arias-Carrión, S Machado, A E Nardi and A C Silva

Affiliation: Laboratory of Panic and Respiration, Institute of Psychiatry–Federal University of Rio de Janeiro - Brazil

Abstract

Depression is the most prevalent psychiatric disorder (16.6%) and is frequently associated with impairments in several areas. Sexual dysfunction (SD) is a prevalent problem with rates ranging from 40–45% in adult women and 20–30% in adult men. A relationship between depression and sexual dysfunction has been shown in the literature although the mechanisms of this association are not yet clear. Many antidepressants, especially selective serotonin reuptake inhibitors (SSRIs), list sexual dysfunction as a side effect. New drug alternatives with fewer side effects have been proposed, and bupropion is one of them. This study aims to review the literature on bupropion and its impact in sexual function on depressed subjects. Most of the studies have noted that bupropion is not only as effective as other antidepressants but has the advantage of a lower impact on sexual functioning. Some other studies have found that bupropion can even enhance sexual function in certain individuals. Bupropion is also effective, when combined with other antidepressants, in treating emergent sexual dysfunction. Bupropion may be an alternative treatment for depression that does not include the sexual side effects associated with most of the prescribed antidepressants available; however, additional research is required


Purchase Online Rights and Permissions

  
  



Article Details

Volume: 13
First Page: 1
Last Page: 1
Page Count: 1
DOI: 10.2174/1871527313666140612112630
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science