A Rapid Protocol for the Synthesis of N-[2-(alkyl/aryl)-4-phenyl-1Himidazol- 1-yl] benzamides via Microwave Technique

ISSN: 2213-3364 (Online)
ISSN: 2213-3356 (Print)


Volume 1, 2 Issues, 2014






Current Microwave Chemistry

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Bimal K. Banik
Department of Chemistry
College of Science & Mathematics
The University of Texas-Pan American
1201 West University Drive
Edinburg, Texas
USA


View Full Editorial Board

Subscribe Purchase Articles Order Reprints


A Rapid Protocol for the Synthesis of N-[2-(alkyl/aryl)-4-phenyl-1Himidazol- 1-yl] benzamides via Microwave Technique

Author(s): Fatih Yılmaz and Emre Mentese

Affiliation: Department of Chemistry, Recep Tayyip Erdogan University, 53100, Rize, Turkey.

Abstract

Benzohydrazides (2a-g) were synthesized starting from iminoester hydrochlorides and benzhydrazide. The treatment of compounds 2a-g with phenylacyl bromide derivatives gave N-[2-(alkyl/aryl)-4-phenyl-1H-imidazol-1-yl] benzamides. The synthetic protocol was performed under microwave irradiation and the lowest quantity of the solvent was used to obtain the best green protocol. This method has been found to be more efficient than others in terms of green chemistry.




Keywords: Acetamidrazone, amide hydrazone, benzamide, benzhydrazide, catalyst-free, hydrazide imide, imidazole, iminoester hydrochloride, green chemistry, microwave irradiation, phenylacyl bromide.

Download Free Rights and Permissions

Article Details

Volume: 1
Issue Number: 1
First Page: 47
Last Page: 51
Page Count: 5
DOI: 10.2174/2213335601999140221111915
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science