Role of Chemokines and Trafficking of Immune Cells in Parasitic Infections

ISSN: 1875-631X (Online)
ISSN: 1573-3955 (Print)


Volume 10, 2 Issues, 2014


Download PDF Flyer




Current Immunology Reviews

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Cecil Czerkinsky
Institut de Pharmacologie Moleculaire et Cellulaire
UMR 7275 CNRS-INSERM-UNISA
660 Route des Lucioles
Valbonne, 06560
France


View Full Editorial Board

Subscribe Purchase Articles Order Reprints


Role of Chemokines and Trafficking of Immune Cells in Parasitic Infections

Author(s): Kathryn E. McGovern and Emma H. Wilson

Affiliation: School of Medicine, Division of Biomedical Sciences, University of California, Riverside, CA, 92521- 0129, USA.

Abstract

Parasites are diverse eukaryotic pathogens that can have complex life cycles. Their clearance, or control within a mammalian host requires the coordinated effort of the immune system. The cell types recruited to areas of infection can combat the disease, promote parasite replication and survival, or contribute to disease pathology. Location and timing of cell recruitment can be crucial. In this review, we explore the role chemokines play in orchestrating and balancing the immune response to achieve optimal control of parasite replication without promoting pathology.

Keywords: CCL21, CCR7, cell trafficking, chemokine, parasite, Toxoplasma.

Download Free Rights and Permissions

Article Details

Volume: 9
Issue Number: 3
First Page: 157
Last Page: 168
Page Count: 12
DOI: 10.2174/1573395509666131217000000
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science