Another Brick in the Wall: Innate Lymphoid Cells of the Intestine

ISSN: 1875-631X (Online)
ISSN: 1573-3955 (Print)


Volume 10, 2 Issues, 2014


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Current Immunology Reviews

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Editor-in-Chief:
Cecil Czerkinsky
Institut de Pharmacologie Moleculaire et Cellulaire
UMR 7275 CNRS-INSERM-UNISA
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Another Brick in the Wall: Innate Lymphoid Cells of the Intestine

Author(s): Frann Antignano and Colby Zaph

Affiliation: Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, V6T1Z3, Canada.

Abstract

Since the recent identification of the expanding innate lymphoid cell (ILC) family, there has been an explosion of interest and research in the ontogeny, phenotype and function of these cells. In the intestine, ILCs are a significant component of the immune cell repertoire in the steady state and several recent studies have identified critical roles for ILCs in homeostasis and disease. In this review, ILC biology will be addressed in the context of intestinal homeostasis, inflammation and immunity to intestinal infections.

Keywords: Helminth, infection, innate lymphocytes, intestine, protozoan.

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Article Details

Volume: 9
Issue Number: 3
First Page: 141
Last Page: 146
Page Count: 6
DOI: 10.2174/1573395509666131128234133
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