ISSN: 1875-6182 (Online)
ISSN: 1871-5257 (Print)
Volume 13, 2 Issues, 2015
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Cardioprotective Effect of Resveratrol and Resveratroloside
Cardiovascular & Hematological Agents in Medicinal Chemistry, 11
): 207-210.Author(s): Sergey E. Naumenko
, Tatiana V. Latysheva
, Michael A. Gilinsky
, Artem D. Rogachev
, Nina I. Komarova
, Nariman F. Salakhutdinov
and Genrikh A Tolstikov
Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 630090, Novosibirsk, Russia.
AbstractCardioprotective effect of resveratrol and resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single intraperitoneal administration of any compound (10 mg/kg) followed by 30-min ischemia and 120-min reperfusion resulted in statistically significant decrease of myocardial infarct area (55.0±4.0% for control group; 40.7±4.4% for the group 1 received resveratrol; 41.6±4.8% for the group 2 received resveratroloside). The cardioprotective effect of resveratroloside was detected for the first time.
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