Benzimidazole Derivatives as Centerally Acting Agents
Current Drug Therapy,
Hassan Y. Aboul-Enein and Ahmed A. El RashedyAffiliation:
Pharmaceutical and Medicinal Chemistry Department, National Research Centre, Dokki, Cairo 12311, Egypt
AbstractBenzimidazole derivatives play an important role in medical field with so many Pharmacological activities, such as selective neuropeptides YY1 receptor antagonists, gamma-amino butyric acid (GABA) agonists, and 5-HT3 antagonists, anticonvulsant and other activities encouraged the development of some more potent and significant compounds. This review presents different substituted benzimidazole derivatives which possess potential along central acting activity.
Anticonvulsant, benzimidazole derivatives, sedative hypnotics, serotoninergic agents.
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