Benzimidazole Derivatives as Centerally Acting Agents

ISSN: 2212-3903 (Online)
ISSN: 1574-8855 (Print)

Volume 10, 2 Issues, 2015

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Current Drug Therapy

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Stefano Palomba
Obstetrics and Gynecology Unit
Institute for Hospitalization and Care Scientific

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Benzimidazole Derivatives as Centerally Acting Agents

Author(s): Hassan Y. Aboul-Enein and Ahmed A. El Rashedy

Affiliation: Pharmaceutical and Medicinal Chemistry Department, National Research Centre, Dokki, Cairo 12311, Egypt


Benzimidazole derivatives play an important role in medical field with so many Pharmacological activities, such as selective neuropeptides YY1 receptor antagonists, gamma-amino butyric acid (GABA) agonists, and 5-HT3 antagonists, anticonvulsant and other activities encouraged the development of some more potent and significant compounds. This review presents different substituted benzimidazole derivatives which possess potential along central acting activity.

Keywords: Anticonvulsant, benzimidazole derivatives, sedative hypnotics, serotoninergic agents.

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Article Details

Volume: 8
Issue Number: 3
First Page: 145
Last Page: 154
Page Count: 10
DOI: 10.2174/1574885508999131119120237

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