Current experimental, bioinformatic and statistical methods used in NMR based metabolomics

ISSN: 2212-3903 (Online)
ISSN: 1574-8855 (Print)


Volume 9, 4 Issues, 2014


Download PDF Flyer




Current Drug Therapy

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Stefano Palomba
Obstetrics and Gynecology Unit
Institute for Hospitalization and Care Scientific
Emilia
Italy


View Full Editorial Board

Subscribe Purchase Articles Order Reprints


Current experimental, bioinformatic and statistical methods used in NMR based metabolomics

Author(s): Helena U. Zacharias, Jochen Hochrein, Matthias S. Klein, Claudia Samol, Peter J. Oefner and Wolfram Gronwald

Affiliation: Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, 93053 Regensburg, Germany.

Abstract

The aim of this contribution is to familiarize the reader with experimental, bioinformatic and statistical strategies currently used in the field of solution NMR based metabolomics. Special emphasis is given to methods that have worked well in our hands. Methods covered include sample preparation, acquisition and processing of NMR spectra, and identification and quantification of metabolites. Further consideration is given to data normalization and scaling, unsupervised and supervised statistical data analysis, the biomedical interpretation of results, and the centralized community-wide storage and retrieval of NMR data.


Purchase Online Rights and Permissions

Article Details

Volume: 8
First Page: 1
Last Page: 1
Page Count: 1
DOI: 10.2174/15748855113089990001
Advertisement

Related Journals



Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science