Clarithromycin Induced Psoriasis in a 37-Year Old Man
Current Drug Safety,
Ahmed Zaiem, Amel Mebazaa, Ghozlane Lakhoua, Talel Badri, Rym Sahnoun, Sarrah Kastalli, Riadh Daghfous and Sihem El AidliAffiliation:
National Center of Pharmacovigilance, 9 Avenue du Dr Zouhaier Essafi 1006, Tunis, Tunisia.
AbstractMany drugs may induce psoriatic lesions or exacerbate preexisting psoriasis. We report an exceptional case of psoriasis vulgaris probably induced by clarithromycin. A 37-year-old man was prescribed for pharyngitis clarithromycin 500mg twice a day. On the third day of treatment, he presented a non pruriginous erythemato-squamous eruption, of trunk and limbs. Skin biopsy showed a typical aspect of psoriasis vulgaris. The drug was interrupted and the patient was treated by topical corticoids with rapid improvement.
Adverse drug reaction, clarithromycin, psoriasis.
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