Clarithromycin Induced Psoriasis in a 37-Year Old Man
Ahmed Zaiem, Amel Mebazaa, Ghozlane Lakhoua, Talel Badri, Rym Sahnoun, Sarrah Kastalli, Riadh Daghfous and Sihem El AidliAffiliation:
National Center of Pharmacovigilance, 9 Avenue du Dr Zouhaier Essafi 1006, Tunis, Tunisia.
AbstractMany drugs may induce psoriatic lesions or exacerbate preexisting psoriasis. We report an exceptional case of psoriasis vulgaris probably induced by clarithromycin. A 37-year-old man was prescribed for pharyngitis clarithromycin 500mg twice a day. On the third day of treatment, he presented a non pruriginous erythemato-squamous eruption, of trunk and limbs. Skin biopsy showed a typical aspect of psoriasis vulgaris. The drug was interrupted and the patient was treated by topical corticoids with rapid improvement.
Adverse drug reaction, clarithromycin, psoriasis.
Purchase Online Order Reprints Order Eprints Rights and Permissions