The High Throughput Biomedicine Unit at the Institute for Molecular Medicine Finland: High Throughput Screening Meets Precision Medicine

ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)


Volume 17, 10 Issues, 2014


Download PDF Flyer




Combinatorial Chemistry & High Throughput Screening

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 23rd of 71 in Chemistry, Applied
  • 47th of 75 in Biochemical Research Methods
  • 152th of 261 in Pharmacology & Pharmacy

Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Rathnam Chaguturu
iDDPartners, 3 Edith Court
Princeton Junction
NJ 08550
USA


View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 2.0
5 - Year: 1.975

The High Throughput Biomedicine Unit at the Institute for Molecular Medicine Finland: High Throughput Screening Meets Precision Medicine

Author(s): Vilja Pietiainen, Jani Saarela, Carina von Schantz, Laura Turunen, Paivi Ostling and Krister Wennerberg

Affiliation: Institute for Molecular Medicine Finland, University of Helsinki, Tukholmankatu 8, 00290 Helsinki, Finland.

Abstract

The High Throughput Biomedicine (HTB) unit at the Institute for Molecular Medicine Finland FIMM was established in 2010 to serve as a national and international academic screening unit providing access to state of the art instrumentation for chemical and RNAi-based high throughput screening. The initial focus of the unit was multiwell plate based chemical screening and high content microarray-based siRNA screening. However, over the first four years of operation, the unit has moved to a more flexible service platform where both chemical and siRNA screening is performed at different scales primarily in multiwell plate-based assays with a wide range of readout possibilities with a focus on ultraminiaturization to allow for affordable screening for the academic users. In addition to high throughput screening, the equipment of the unit is also used to support miniaturized, multiplexed and high throughput applications for other types of research such as genomics, sequencing and biobanking operations. Importantly, with the translational research goals at FIMM, an increasing part of the operations at the HTB unit is being focused on high throughput systems biological platforms for functional profiling of patient cells in personalized and precision medicine projects.

Keywords: Chemical biology, high throughput screening, microarrays, miniaturization, personalized medicine, RNAi, translational research.

Download Free Rights and Permissions

Article Details

Volume: 17
Issue Number: 4
First Page: 377
Last Page: 386
Page Count: 10
DOI: 10.2174/1386207317666140323195927
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science