Functional Genomics Down Under: RNAi Screening in the Victorian Centre for Functional Genomics

ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)


Volume 17, 10 Issues, 2014


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Combinatorial Chemistry & High Throughput Screening

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Functional Genomics Down Under: RNAi Screening in the Victorian Centre for Functional Genomics

Author(s): Daniel W. Thomas, Cathryn M. Gould, Yanny Handoko and Kaylene J. Simpson

Affiliation: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

Abstract

The Victorian Centre for Functional Genomics (VCFG) is an RNAi screening facility housed at the Peter MacCallum Cancer Centre in Melbourne, Australia. The Peter Mac is Australia’s largest dedicated Cancer Research Institute, home to a team of over 520 scientists that focus on understanding the genetic risk of cancer, the molecular events regulating cancer growth and dissemination and improving detection through new diagnostic tools (www.petermac.org). Peter Mac is a well recognised technology leader and established the VCFG with a view to enabling researchers Australia and New Zealand-wide access to cutting edge functional genomics technology, infrastructure and expertise. This review documents the technology platforms operated within the VCFG and provides insight into the workflows and analysis pipelines currently in operation.

Keywords: RNAi, functional genomics, high throughput screening, high content imaging.

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Article Details

Volume: 17
Issue Number: 4
First Page: 343
Last Page: 355
Page Count: 13
DOI: 10.2174/1386207317666140323134315
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