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Articles


For the Month of September,
2011

Heme Oxygenase-Derived Carbon Monoxide Restores Vascular Function in Type 1 Diabetes, 2008, Vol 2-4 Pp. 290-300

A Comparative Study of the CYP450 Inhibition Potential of Marketed Drugs Using Two Fluorescence Based Assay Platforms Routinely Used in the Pharmaceutical Industry, 2011, Vol 5-1 Pp. 30-39

A Comparative Study on the Stability of Silybin and That in Silymarin in Buffers and Biological Fluids, 2009, Vol 3-2 Pp. 115-119

Effects of Histidine-Tag on Recombinant Human Cytochrome P450 3A5 Catalytic Activity in Reconstitution Systems, 2009, Vol 3-4 Pp. 207-211

Comparative Pharmacokinetics and Metabolism Studies in Lean and Diet- Induced Obese Mice: An Animal Efficacy Model for 11β -Hydroxysteroid Dehydrogenase Type 1 (11β -HSD1) Inhibitors, 2011, Vol 5-1 Pp. 55-63

An In Vitro, High Throughput, Seven CYP Cocktail Inhibition Assay for the Evaluation of New Chemical Entities Using LC-MS/MS, 2011, Vol 5-1 Pp. 17-24

High-Throughput, 384-Well, LC-MS/MS CYP Inhibition Assay Using Automation, Cassette-Analysis Technique and Streamlined Data Analysis, 2011, Vol 5-3 Pp. 220-230

Impact of Impurities on IC50 Values of P450 Inhibitors, 2011, Vol 5-3 Pp. 156-162

The Use of 1-Aminobenzotriazole in Differentiating the Role of CYPMediated First Pass Metabolism and Absorption in Limiting Drug Oral Bioavailability: A Case Study, 2008, Vol 2-2 Pp. 120-124

Quantitative Analysis of UGT2B28 mRNA Expression by Real-Time RT-PCR and Application to Human Tissue Distribution Study, 2011, Vol 5-3 Pp. 202-208




For the Month of August,
2011

Higher Throughput Human Hepatocyte Assays for the Evaluation of Time-Dependent Inhibition of CYP3A4, 2011, Vol 5-3 Pp. 183-191

Investigations Into the Drug-Drug Interaction Potential of Tapentadol in Human Liver Microsomes and Fresh Human Hepatocytes, 2008, Vol 2-1 Pp. 67-75

Esterase Activities in the Blood, Liver and Intestine of Several Preclinical Species and Humans, 2009, Vol 3-2 Pp. 70-77

Reversible Covalent Binding of Neratinib to Human Serum Albumin In Vitro, 2010, Vol 4-4 Pp. 220-227

Human Liver Enzymes Responsible for Metabolic Elimination of Tyramine, a Vasopressor Agent from Daily Food, 2011, Vol 5-3 Pp. 216-219

High-Throughput, 384-Well, LC-MS/MS CYP Inhibition Assay Using Automation, Cassette-Analysis Technique and Streamlined Data Analysis, 2011 Vol 5-3 Pp. 220-230

A Comparative Study of the CYP450 Inhibition Potential of Marketed Drugs Using Two Fluorescence Based Assay Platforms Routinely Used in the Pharmaceutical Industry, 2011, Vol 5-1 Pp. 30-39

A Multi-Endpoint Evaluation of Cytochrome P450 1A2, 2B6 and 3A4 Induction Response in Human Hepatocyte Cultures After Treatment with β - Naphthoflavone, Phenobarbital and Rifampicin, 2010, Vol 4-4 Pp. 185-194

Allosteric Modulation of SULT2A1 by Celecoxib and Nimesulide: Computational Analyses, 2008, Vol 2-3 Pp. 198-204

Alpha-1-Adrenergic Receptor Blockade Modifies Insulin-Regulated Aminopeptidase (IRAP) Activity in Rat Prostate and Modulates Oxytocin Functions, 2011, Vol 5-3 Pp. 192-196


For the Month of July, 2011

Investigations Into the Drug-Drug Interaction Potential of Tapentadol in Human Liver Microsomes and Fresh Human Hepatocytes, 2008, 2-1 Pp. 67-75

Assessment of the Inactivation Potential of Desethylamiodarone on Human CYP1A1, 2010, Vol 4-1 Pp. 9-14

Comparative Bioequivalence Study of Three Formulations of Enrofloxacin in Sheep, 2011, Vol 5-2 Pp.85-91

Pharmacokinetics of Pseudoephedrine in Rats, Dogs, Monkeys and Its Pharmacokinetic-Pharmacodynamic Relationship in a Feline Model of Nasal Congestion, 2010, Vol 4-2 Pp.56-61

Toxicokinetic Interaction Between Quetiapine and Antiretroviral Therapy Following Quetiapine Overdose, 2010, Vol 4-1 Pp. 7-8

Nandrolone Decanoate Enhances the Activities of Cholanthrene Induced Glutathione-s-Transferase in Liver Tissue of Albino Mice, 2010, Vol 4-1 Pp. 1-6

Influence of ABCB1 Gene Polymorphisms and P-Glycoprotein Activity on Cyclosporine Pharmacokinetics in Peripheral Blood Mononuclear Cells in Healthy Volunteers, 2008, Vol 2-2 Pp. 76-82

Aldehyde Oxidase Activity and Inhibition in Hepatocytes and Cytosolic Fraction from Mouse, Rat,Monkey and Human, 2008, Vol 2-3 Pp. 176-183

Allelic Variations in CYP2D6 Gene and Susceptibility to Cervical Cancer, 2007, Vol 1-4 Pp. 276-280

An Evaluation of Ondansetron Binding Interactions with Human Cytochrome P450 Enzymes CYP3A4 and CYP2D6, 2010, Vol 4-1 Pp. 25-30




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