
Editor-in-Chief:
Dr. William A. Banks, MD
VAPSHCS/GRECC S-182
Building 1, Room 810A
1600 S. Columbian Way
Seattle, WA 98108
USA
Section Editors:
Howard Gendelman (University of Nebraska Med. Ctr., Omaha, NE, USA)
HIV Agents
Emilio Jirillo (Bari University, Bari, Italy)
Immune Agents
Alexander V. Kabanov (University of Nebraska Medical Center, Omaha, NE, USA)
Nanotechnology
Abba Kastin (Pennington Biomed. Res. Ctr., Baton Rouge, LA, USA)
Endocrine and Metabolic Agents
Gregory Lip (City Hospital, Birmingham, UK)
Anti-hypertensive Agents
Dimitri Mikhailidis (Royal Free Hospital, London, UK)
Cardiovascular/Hematologic Agents
Weihong Pan (Pennington Biomed. Res. Ctr., Baton Rouge, LA, USA)
Neurogenesis and Neural Repair
Rami Reddy (RR Labs Inc., San Diego, CA, USA)
Computer Assisted Drug Design
Editorial Advisory Board:
Mohammad Abdollahi (Tehran
University of Medical Sciences, Tehran, Iran)
Scott A. Biller (Novartis Institutes for
BioMedical Research, Cambridge, MA, USA)
Steven J. Brickner (Pfizer, Groton, CT, USA)
D. A. Butterfield (University of Kentucky,
Lexington, KY, USA)
Giovanni Capranico (Istituto Nazionale Tumori,
Milan, Italy)
Craig E. Caufield (Wyeth-Ayerst Research,
Princeton, NJ, USA)
Daniel T.W. Chu (Chiron Corporation, Emeryville,
CA, USA)
Errol B. De Souza (Neurocrine Biosciences,
San Diego, CA, USA)
Elisabeth G.E. De Vries (Univ. of Groningen,
Groningen, Netherlands)
Stevan W. Djuric (Abbott Laboratories, Abbott
Park, IL, USA)
Annette M. Doherty (Pfizer Global R & D, Sandwich,
Kent, UK)
Roland E. Dolle (Pharmacopeia, Inc., Princeton,
NJ, USA)
Catherine L. Farrell (Amgen, Inc.,Thousand
Oaks, CA, USA)
Roger M. Freidinger (Merck Res. Laboratories,
West Point, PA, USA)
Donald R. Gehlert (Lilly Research Laboratories,
IN, USA)
Nigel H. Greig (National Institutes of Health,
Baltimore, MD, USA)
James M. Hamby (Parke-Davis, Pharm. Res.
Ann Arbor, MI, USA)
Tingjun Hou (Soochow University, Suzhou, Jiangsu, China)
Graham Johnson (Bristol-Myers Squibb, CT,
USA)
Marlys Koschinsky (Queen's University, Kingston,
Canada)
Kit S. Lam (UC Davis Cancer Center, Sacramento,
CA, USA)
Wolfgang Langhans (Swiss Federal Inst. Tech.,
Schwerzenbach, Switzerland)
Hans Marquardt (Universität Hamburg,
Hamburg, Germany)
John E. Morley (St. Louis Univ. Health Sciences
Center, St. Louis, MO, USA)
John H. Musser (Glycomed, Alameda, CA, USA)
Martin Petkovich (Queen's University, Kingston,
Canada)
Waldemar Priebe (University of Texas, Houston,
TX, USA)
Des R. Richardson (University of Sydney,
Sydney, NSW, Australia)
Andrew V. Schally Nobel
laureate (VAMC, New Orleans, LA, USA)
George J. Schroepfer Jr. (Rice University,
Houston, TX, USA)
Linus L. Shen (Abbott Laboratories, Abbott
Park, IL, USA)
Seiji Shioda (Showa Univ. Sch. of Medicine,
Shinagawa-ku, Tokyo, Japan)
Jeffrey D. Shmitt (Mol. Design & IT Group,
North Carolina, USA)
William S. Sly (Saint Louis University School
of Medicine, St. Louis, MO, USA)
Claudio Soto (University of Texas Medical
Branch, Galveston, TX, USA)
Claudiu T. Supuran (Universita degli Studi
di Firenze, Florence, Italy)
Tetsuya Terasaki (Graduate School of Pharmaceutical,
Tohoku University, Sendai, Japan)
Nese Tuncel (Osmangazi University, Eskisehir,
Turkey)
Franco Zunino (Istituto Nazionale Tumori,
Milan, Italy)
Executive Guest Editors:
Old and new Pharmacotherapies
in the Management of Patients with Alcohol Dependence
Giovanni Addolorato/Lorenzo Leggio (Italy)
New Strategies in the Search of Antipsychotic
Drugs
Albert Adell (Spain)
Structural Insights of the MHC Molecule
in the Design of Vaccines
Vasso Apostolopoulos (Australia)
Targeted Therapeutics - From Chemical
Structures to Diagnostic and Therapeutic Agents
Christine Armbruster (Austria)
The Blood Brain Barrier in Health &
Disease
William A. Banks (USA)
Phosphodiesterase 5 Inhibitors: Pharmacology
and Therapeutic Perspectives
Giuseppe Barbaro (Italy)
The next Generation of Recombinant Human
Immunotoxins
Stefan Barth (Germany)
Bipolar Depressions, Diagnosis and
Treatment
Franco Benazzi (Italy)
Anti-Cancer Drugs
Elke S. Bergmann-Leitner (USA)
The HIV-1 Envelope Protein as Vaccine
Candidate and Therapeutic Target
Ben Berkhout/Rogier Sanders (The Netherlands)
Anti-Angiogenesis Agents
Maurizio Botta (Italy)
Anti-Cancer Agents
Giovanni Capranico (Italy)
Oxidative Stress, Inflammation and type
2 Diabetes
Xilin Chen (USA)
Current Perspectives in the use of PUFA
for Treatment of Human Diseases
Antonio Cherubini (Italy)
Molecularly Targeted Therapies in Breast
Cancer Bone Metastasis
Philippe Clezardin (France)
Targeting Nitric Oxide for Tumor Therapy
Antonio Contestabile (Italy)
Pharmacological Modulation of Ischemia-Reperusion
(I/R) Injury with Emphasis on Liver I/R Injury
Brian R. Davidson/Dimitri P Mikhailidis/George
K Glantzounis (UK)
Death Receptor Ligands
E.G. Elisabeth de Vries (The Netherlands)
The Metabolic Treatment of Coronary
Artery Disease and Heart Failure
Pericle Di Napoli (Italy)
Physical and Chemical Agents Inducing
Cell Death and Differentiation
Roberta Di Pietro (Italy)
Parasite Polyamines as Pharmaceutical
Targets
Marcos André Vannier dos Santos (Brazil)
Pharmaceutical Design of Novel Anticancer
Agents: A Lesson from Nature
Ping Dou (USA)
The Multifactorial Nature of AD and
related Therapeutic Strategies
Maria do carmo Carreiras (Portugal)
ECM in Health and Disease
Johannes A. Eble (Germany)
Pleiotropic Effects of Drugs used for
the Prevention of Cardiovascular Diseases
M. Elisaf/E. Liberopoulos (Greece)
News in Therapy of Cardiomyopathy
Giovanni Fazio (Italy)
Biased Agonism at 7TMRs
Chris S. Flordellis (Greece)
Perspectives in Psychopharmacological
Neuroimaging
Paolo Fusar-Poli (Italy)
Adipose Stem Cells as Pharmacological
Targets and Discovery Tools
Jeffrey M. Gimble / Mark E. Nuttall (USA)
Tracers and Techniques for non-invasive
in vivo Imaging of Beta-cells
Martin Gotthardt (The Netherlands)
Neuropeptide-based Drug Design
Illana Gozes (Israel)
Pharmacogenetics
Henk-Jan Guchelaar (The Netherlands)
Resistance in Gram-negative Pathogens:
A Threat to Global Health
Nancy D. Hanson (USA)
Novel Approach for Potential Therapeutic
Drugs of Schizophrenia
Kenji Hashimoto (Japan)
Membrane Channels as Therapeutic Targets/Therapeutic
Potential of Peptide Motifs
Jean-Claude Hervé (France)
Bisphosphonates and Bone Diseases
Dominique Heymann (France)
Perspectives of Pharmacokinetics and
Metabolism in Drug Design
Yunsheng Hsieh (USA)
Therapeutic Manipulation of the Immune
System: Old and new Approaches
Emilio Jirillo (Italy)
Cell Adhesion Molecules: Function,
Drug-Design and Biomaterials
Seetharama D.S. Jois (USA)
The Role of Radiopharmaceuticals in
Drug Development
Kairemo Kalevi (Finland)
Pathophysiological basis and Prospects
for Novel Therapies in Inflammatory Bowel Disease
Osamu Kanauchi (Japan)
Bipolar Disorder: Clinical Staging as
a means to Guide Pharmacological Interventions
Flávio Kapczinski (Brazil)
Radiopharmaceuticals in Drug Discovery
and Development
Michael Kassiou (Australia)
New Therapeutic Strategies for Treatment
Neurodegenerative Diseases
Aleksey Kazantsev (USA)
The hypoxia-inducible factor (HIF) Pathway
as a target for Prevention and Treatment of Clinical Manifestations
Thomas Kietzmann (Germany)
Current status of Drug Eluting Stents
Nicholas Kipshidze (USA)
Anti-Hypertensive Agents in Relation
to Modifying Coronary Risk Factors
Aurelio Leone (Italy)
Antihypertensive Drugs
Gregory Y.H. Lip (UK)
New Antidepressant Drugs Beyond Monoaminergic
Design
Francisco Lopez-Munoz (Spain)
The Endocannabinoid System in Neuroinflammatory
Diseases
Mauro Maccarrone (Italy)
Angiogenesis gene therapy: New tools
and Targets to Stimulate a Mature Neovasculature
Paolo Madeddu (UK)
Drugs Targeting atherosclerosis: Current
and Emerging Approaches
Vangelis Manolopoulos (Greece)
Angiogenesis Agents
Cezary Marcinkiewicz (USA)
Therapeutic Angiogenesis and Regeneration
in Cardiovascular Diseases
Takahashi Masafumi (Japan)
Therapeutic Intervention on virus Assembly
Mauricio G. Mateu (Spain)
Erythropoietin
Peter van der Meer (USA)
Effect on Serum Uric Acid Levels of
Drugs Prescribed for Indications other than Treating Hyperuricaemia;
2) Lipid Lowering Treatment - An Update
Dimitri P. Mikhailidis (UK)
New generation cancer vaccines: From
Tumor Immunology to Clinical Applications
Simone Mocellin (Italy)
Applications of ACE Inhibitors and A2
Receptor Blockers
Agostino Molteni (USA)
In silico approaches in G protein-coupled
Receptors (GPCRs) Drug Discovery: Quo Vadis?
Stefano Moro (Italy)
ADAM family members as Therapeutic
Targets
Marcia Moss (USA)
Exploiting Multivalency in Drug Design
Diego Munoz-Torrero (USA)
Spinal Cord Injury and Repair
Weihong Pan (USA)
Current Perspectives and Future Challenges
in the Treatment of Arterial Stiffness and Central Hemodynamics
Theodoros Papaioannou (Greece)
HIV Drug Design (Anti-HIV Agents)
Keykavous Parang (USA)
Nicotinamide Adenine Dinucleotide Biology
and Disease
W. Todd Penberthy (USA)
Molecular Mechanisms of Cancer Cell
Death
Ricardo Perez-Tomas (USA)
HIV Entry: Achievements and Challenges
Stefan Pohlmann (Germany)
Central Neuropeptidergic Systems as
Targets for Novel Psychiatric Drug Development
Robert Ring (USA)
Computer-assisted Drug design and discover
from nature
Judith Rollinger (Austria)
HIV Drug Design and Therapy
Ted M. Ross (USA)
Frontiers in Child Psychiatric Pharmacological
Treatment
A. Rothenberger (Germany)
Enzyme Inhibition
Michel Salzet (France)
Inhibitions of Tumor-associated Inflammation
to Fight Cancer
Raymond Schiffelers (The Netherlands)
Molecular Biology of Sexual Dysfunction
Allen D. Seftel (USA)
Ion Channels as Therapeutic Targets
for Neuropathic Pain
Char-Chang Shieh (USA)
Protein Misfolding Disorders
Claudio Soto (Switzerland)
New Mechanisms of Bacterial Resistance
Iris Spiliopoulou (Greece)
Latest Achievements in Zinc Enzymes:
Structure, Inhibition & Drug Design
Georgios A. Spyroulias (Greece)
Autoimmune Diseases
D. Stahl/W. Sibrowski (Germany)
Carbonic Anhydrases as Drug Targets
Claudiu T. Supuran (Italy)
Ion Channels as a Target for Drug Design
Kwok-Keung Tai (USA)
The Adverse Effects of Chronic Inflammation
on Cardiovascular Health
Paul-Peter Tak/Radjesh Bisoendial (The Netherlands)
The Search of Targets for Novel Antipsychotic
Drugs
Akihiro Takano (Sweden)
Gastrointestinal (GI) Research
Koji Takeuchi (Japan)
Current Perspectives on Muscle Regeneration
and Diseases
Gianluca Tettamanti/ Annalisa Grimaldi (Italy)
Recent Advances in Developmental Toxicology
Gian Mario Tiboni (Italy)
Adipocytokines and Fatty Liver Disease:
Key Mediators Linking Fat and Inflammation
Herbert Tilg (Austria)
The Mechanisms of Bilirubin Cytotoxicity
and its Translational Meanings
Claudio Tiribelli (Italy)
Treatment of Neuroblastoma: From MYCN-based
Therapy to new Therapies
Gian Paolo Tonini (Italy)
Regulatory Peptides
Nese Tuncel (Turkey)
The Human Microbiome - a Therapeutic
Target for Prevention and Treatment of Chronic Disease
Kieran Tuohy (UK)
Pharmaceutical and Cellular Strategies
in Prophylaxis and Treatment of Graft-versus-Host Disease
George Tuszynski (USA)
Citokines and Inflammation Markers in
Ischemic Stroke
Antonino Tuttolomondo (Italy)
Antisense Oligonucleotide
Bruce D. Uhal (USA)
Drug-induced Arrhythmias
Jamie Vandenberg (Australia)
Cytokine Genetics & Pharmacogenomics
Koen Vandenbroeck (The Netherlands)
Pharmacological Brain Imaging in the
Healthy and Sick Brain
Freddy van der Veen (The Netherlands)
High Density Lipoproteins: anno 2008
Sophie van Linthout (UK)
Possible new Pharmacological Strategies
for the Treatment of Supraventricular Arrhythmias
Andras Varro (Hungary)
Action and Evolution of Immunomodulatory
Drugs
Mariateresa Ventura (Italy)
Glucocorticoids from Chemistry to Clinics
Forunato Vesce (Italy)
Oxidative Stress and Cellular Homeostasis
Victor Manuel Victor (Spain)
Targets of Metabolic Toxicity of HIV
Antiretroviral Drugs: The Multiple Roads to Lipodystrophy
and Metabolic Syndrome
Francesc Villarroya (Spain)
Protein-Protein Interactions. Application
to the Development of New Antiviral Agents for the Treatment
of HIV Infection
Michael Walker (USA)
Current Formulation Techniques of Drug
Delivery Devices
Chi-Hwa Wang (Singapore) |