Progress of Cancer Stem Cells in Retinoblastoma

Title:Progress of Cancer Stem Cells in Retinoblastoma

Volume: 19 Issue: 8

Author(s): Nan Wang and Jian-Min Ma*

Affiliation:

• Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China

Keywords: Retinoblastoma, cancer stem cells, drug resistance, Wnt pathway, targeted therapy, tumor.

Abstract: The theory of cancer stem cells is a breakthrough discovery that offers exciting possibilities for comprehending the biological behavior of tumors. More and more evidence suggests that retinoblastoma cancer stem cells promote tumor growth and are likely to be the origin of tumor formation, drug resistance, recurrence, and metastasis. At present, some progress has been made in the verification, biological behavior, and drug resistance mechanism of retinoblastoma cancer stem cells. This article aims to review the relevant research and explore future development direction.

Cite this article as:

Wang Nan and Ma Jian-Min*, Progress of Cancer Stem Cells in Retinoblastoma, Current Stem Cell Research & Therapy 2024; 19 (8) . https://dx.doi.org/10.2174/011574888X252989230921065809